The SNX9/SH3PX1 Polyclonal Antibody, Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to SNX9, and Sorting Nexin 9. This antibody recognizes Mouse antigen. The SNX9/SH3PX1 Polyclonal Antibody, Cy7 Conjugated has been shown to work in the following applications: Western Blot.
Description
Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate