The IDUA Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to alpha-L-iduronidase, and IDUA. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The IDUA Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). [provided by RefSeq, Jul 2008]