The ATM (Tyr170) Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody. This antibody recognizes Homo Sapiens, and Human antigen. The ATM (Tyr170) Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Immunohistochemistry - fixed.
Description
ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases)