Progesterone Receptor B (C1A2) Rabbit mAb 3157S from Cell Signaling Technology

Product Specs
ItemProgesterone Receptor B (C1A2) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number3157S
ClonalityMonoclonal
NCBI Full Gene Nameprogesterone receptor
ApplicationsWB, FCM, ICC, IF, IHC-p
ReactivityHuman (Hu)
Research AreaNuclear Receptor Signaling
CloneC1A2
Molecular Weight118
NCBI Gene AliasesNR3C3, PR
HostRabbit
TargetProgesterone receptor
Quantity100 µl

Questions and Answers

Can this antibody be used to study progesterone receptor expression in endometrial cancer cells?

Yes, the Progesterone Receptor B (C1A2) Rabbit mAb has been utilized in studies involving endometrial cancer cells. For instance, it was employed in Western blotting to assess PR expression in endometrial cancer cell lines, demonstrating its effectiveness in detecting PR levels in this context ().

Is this antibody suitable for use in immunohistochemistry applications?

The Progesterone Receptor B (C1A2) Rabbit mAb has been shown to work in immunohistochemistry applications, as indicated by its use in various studies to visualize PR expression in tissue samples, including endometrial tissues ().

What is the significance of using this antibody in breast cancer research?

This antibody has been cited in research focusing on breast cancer, particularly in studies examining the relationship between progesterone receptor expression and tumor characteristics. For example, it was used to analyze PR expression in MCF7 cells, which are a model for estrogen receptor-positive breast cancer ().

Does this antibody cross-react with other progesterone receptor family members?

No, the Progesterone Receptor B (C1A2) Rabbit mAb is specific for the progesterone receptor B protein and does not cross-react with other members of the progesterone receptor family, ensuring accurate detection of the target protein in experimental settings.

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Estrogen Receptor Expression Changes After Puberty in the Porcine Anterior Cruciate LigamentbioRxivMarch 14, 2026Jacob D. Thompson, Matthew B. Fisher(1:1000, 2118S Cell Signaling Technologies) overnight in 5% BSA at 4°C. Progesterone receptor beta (PRβ, 3157 Cell Signaling Technologies) could not be validated from the positive uterine control in western blot,

(2) Dual PI3K and HDAC inhibitor, CUDC-907, effectively inhibits endometrial cancer growth in vitro and in vivoFrontiers in OncologyNovember 4, 2025Xudong Zhang, Vanessa Lazaro-Camp, Tianyue Li, Amanda Qi, Lingyun Lan, Lillie Lamont, Lu Zhao, Maggie R. Meehan, Sophia N. Gardner, Wendy Meng, et al.following antibodies were purchased from Cell Signaling Technology (Danvers, MA, USA): PR (#3153 and #3157), AKT (#9272), phospho‐AKT (Ser473, #4060), FOXO1(#2880), H3Ace (#39139), Myc (#13987), PARP (#9542),

(3) Promegestone Prevents Lipopolysaccharide-Induced Cervical Remodeling in Pregnant MiceCellsFebruary 7, 2025Nadeem A, Nadeem L, Lye SJ, Shynlova O.7720-17004, Hercules, CA, USA), PRA/B (ThermoFisher, MA5-14505, Danvers, MA, USA), PRB (Cell Signalling, 3157, Danvers, MA, USA), and rabbit IgG (BioLegend, 400601, Hercules, CA, USA) overnight at 4 °C. On the

(4) A Pilot Study on the Co-existence of Diabetes and Endometriosis in Reproductive-Age Women: Potential for Endometriosis ProgressionReproductive SciencesAugust 1, 2023Iad Alhallak, Charles M. Quick, Garrett L. Graham, Rosalia C. M. Simmen,Millipore Sigma/05–824,AB_310195,1:200 Ki67,Abcam/Ab16667,AB_302459,1:200 Progesterone Receptor (total),Santa Cruz/sc7208,AB_2164331,1:200 Progesterone Receptor-B,Cell Signaling/3157S,AB_2252606,1:400 Phosphatase and Tensin homologue,Cell Signaling/138G6,AB_823618,1:200 Macrophage

(5) Utilizing an Endogenous Progesterone Receptor Reporter Gene for Drug Screening and Mechanistic Study in Endometrial CancerCancers (Basel)October 6, 2022Yiyang Li, Wei Zhou, Xiangbing Meng, Sarina D. Murray, Long Li, Abby Fronk, Vanessa J. Lazaro-Camp, Kuo-kuang Wen, Meng Wu, Adam Dupuy, et al.Alexidine hydrochloride was purchased from Cayman (Ann Arbor, MI, USA). Antibodies against PRA/B (#3153), PRB (#3157), FOXO1 (#2880), p21 (#2947), cyclin D1 (#2926), and Myc (#13987) were from Cell Signaling (Danvers,

(6) Possible significance of degeneration and decreased expression of progesterone receptor in postmenopausal uterine leiomyomaBMC Women's HealthAugust 16, 2022Saki Tanioka, Ryoko Asano, Reina Wakabayashi, Hiroyuki Hayashi, Hiroyuki ShigetaUSA, #8757), and anti-progesterone receptor B (C1A2) rabbit mAb (1:800, Cell Signaling Technology, #3157). Staining was performed according to the manufacturer’s protocol. The staining of ER and PRAB used

(7) A human breast atlas integrating single-cell proteomics and transcriptomicsDevelopmental cellJune 6, 2022Gray GK, Li CM, Rosenbluth JM, Selfors LM, Girnius N, Lin JR, Schackmann RCJ, Goh WL, Moore K, Shapiro HK, et al.,Cell Signaling Technology,Cat#13258; RRID: AB_2632959 "PRβ (164Dy, CyTOF)",Cell Signaling Technology,Cat#3157; RRID: AB_2252606 "GATA3 (141Pr, CyTOF)",Miltenyi Biotec,Cat#130-108-061; RRID: AB_2651829 "MUC1 (149Sm,

(8) Estetrol Combined to Progestogen for Menopause or Contraception Indication Is Neutral on Breast CancerCancers (Basel)May 20, 2021Anne Gallez et al.S118-ERα (16J4, #2511, Cell signaling Technology, Danvers, MA 01923, USA), anti-PR (D8Q2J, #8757, C1A2, #3157, Cell signaling Technology, Danvers, MA 01923, USA), anti-GAPDH (#MAB374, Cell signaling Technology,

(9) Roles of OB-Fold Proteins in Replication StressFrontiers in Cell and Developmental BiologySeptember 11, 2020Dinh-Duc Nguyen, Eugene Y. Kim, Pau Biak Sang, Weihang ChaiM. A., and Shippen, D. E. (2010). Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. Qin, Z., Bi, L., Hou, X. M., Zhang, S., Zhang, X., Lu, Y., et al. (2020). Human RPA activates

(10) 53BP1: a DSB escortGenes & DevelopmentJanuary 4, 2020Zachary Mirman, Titia de LangeJA, Beilstein MA, Shippen DE. 2010. Evolution of CST function in telomere maintenance. Cell Cycle 9: 3157–3165. doi:10.4161/cc.9.16.12547 Ray Chaudhuri A, Nussenzweig A. 2017. The multifaceted roles of PARP1

(11) Structural Biology of TelomeraseCold Spring Harbor Perspectives in BiologyDecember 1, 2019Yaqiang Wang, Lukas SuÅ¡ac, Juli FeigonJA, Beilstein MA, Shippen DE. 2010. Evolution of CST function in telomere maintenance. Cell Cycle 9: 3157–3165. Qiao F, Cech TR. 2008. Triple-helix structure in telomerase RNA contributes to catalysis. Nat

(12) The Use of Alcohol versus Dry Care for the Umbilical Cord in Newborns: A Systematic Review and Meta-analysis of Randomized and Non-randomized StudiesCureusJuly 8, 2019Hassan Al-ShehriRandomized clinical trial. Regarding the incidence of omphalitis, its outcomes were studied in 11 articles (3157 infants). However, RRs were not estimable in four studies since there were no reported infants with omphalitis.

(13) At the Beginning of the End and in the Middle of the Beginning: Structure and Maintenance of Telomeric DNA Repeats and Interstitial Telomeric SequencesGenes (Basel)February 5, 2019Anna Y. Aksenova, Sergei M. MirkinBeilstein, M.A.; Shippen, D.E. Evolution of CST function in telomere maintenance. Cell Cycle 2010, 9, 3157–3165. [CrossRef] [PubMed] 180. Stewart, J.A.; Wang, F.; Chaiken, M.F.; Kasbek, C.; Chastain, P.D.; Wright,

(14) Tpz1^TPP1 prevents telomerase activation and protects telomeres by modulating the Stn1-Ten1 complex in fission yeastCommunications biologyJanuary 1, 2019Mennie AK, Moser BA, Hoyle A, Low RS, Tanaka K, Nakamura TM.1633–1646 (2015). Price, C. M. et al. Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165 (2010). Huang, C., Dai, X. & Chai, W. Human Stn1 protects telomere integrity by promoting efﬁcient

(15) Understanding diversity in telomere dynamicsPhilosophical Transactions of the Royal Society B: Biological SciencesMarch 5, 2018Pat Monaghan, Dan T. A. Eisenberg, Lea Harrington, Dan NusseyJA, Beilstein MA, Shippen DE. 2010 Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. (doi:10.4161/cc.9.16.12547) Ishikawa F, Naito T. 1999 Why do we have linear chromosomes? A matter

(16) Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid ArthritisMediators of InflammationJanuary 18, 2018Manuela Di Franco, Bruno Lucchino, Fabrizio Conti, Guido Valesini, Francesca Romana Spinellipreserving dimethylarginine-dimethylaminohydrolase activity,” Endocrinology, vol. 149, no. 6, pp. 3148–3157, 2008. [44] M. González, C. Flores, J. D. Pearson, P. Casanello, and L. Sobrevia, “Cell signalling-mediating

(17) Structural biology of telomerase and its interaction at telomeresCurrent Opinion in Structural BiologyDecember 1, 2017Yaqiang Wang, Juli FeigonJA, Beilstein MA, Shippen DE. Evolution of CST function in telomere maintenance. Cell Cycle. 2010; 9:3157–3165. [PubMed: 20697207] 24. Parks JW, Stone MD. Single-Molecule Studies of Telomeres and Telomerase.

(18) A Matter of Scale and Dimensions: Chromatin of Chromosome Landmarks in the FungiMicrobiology SpectrumAugust 25, 2017Allyson A. Erlendson, Steven Friedman, Michael FreitagJA, Beilstein MA, Shippen DE. Evolution of CST function in telomere maintenance. Cell Cycle. 2010; 9:3157–65. 12547 [pii]. DOI: 10.4161/cc. 9.16.12547 [PubMed: 20697207] 83. Kothe GO, Kitamura M, Masutani M,

(19) Drosophila: Retrotransposons Making up TelomeresVirusesJuly 19, 2017Elena CasacubertaBeilstein, M.A.; Shippen, D.E. Evolution of CST function in telomere maintenance. Cell Cycle 2010, 9, 3157–3165. [CrossRef] [PubMed] Morgunova, V.; Akulenko, N.; Radion, E.; Olovnikov, I.; Abramov, Y.; Olenina,

(20) Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding YeastG3 Genes|Genomes|GeneticsJuly 1, 2017Eva-Maria Holstein, Greg Ngo, Conor Lawless, Peter Banks, Matthew Greetham, Darren Wilkinson, David LydallStewart, M. A. Beilstein et al., 2010 Evolution of CST function in telomere maintenance. Cell Cycle 9(16): 3157–3165. Sugitani, N., and W. J. Chazin, 2015 Characteristics and concepts of dynamic hub proteins in DNA

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Progesterone Receptor B (C1A2) Rabbit mAb

Progesterone Receptor B (C1A2) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Progesterone Receptor B (C1A2) Rabbit mAb from Cell Signaling Technology

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