DAP12 (D7G1X) Rabbit mAb 12492S from Cell Signaling Technology

Product Specs
ItemDAP12 (D7G1X) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12492S
Quantity100 µl
ApplicationsW, W-S, IP
ReactivityH, M
HostRabbit
ClonalityMonoclonal
Research AreaImmunology and Inflammation
CloneD7G1X
Molecular Weight10, 12
TargetDap12
NCBI Full Gene Nametransmembrane immune signaling adaptor TYROBP
NCBI Gene AliasesDAP12, KARAP, PLOSL, PLOSL1

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) TREM2-mediated microglial phagocytosis of inhibitory synapses contributes to prolonged FS-induced epileptogenesisCell Death DiscoveryApril 11, 2026Xiaoqian Wang, Hua Zhou, Yujie Zhai, Yunrong Zhang, Yao Cheng, Yi Yuan, Wenxiao Cao, Anqing Gao, Mengshuang Liu, Qiaoyun Wang, et al.Cell Signaling Technology), anti-Phospho-DAP12 (1:1000; 32308; Cell Signaling Technology), anti-DAP12 (1:1000; 12492; Cell Signaling Technology) or anti-GAPDH (1;1000; AB-P-R001; Goodhere) with slow shaking overnight

(2) A ligand-mimetic anti-TREM2 agonist antibody elevates soluble TREM2 and ameliorates pathology in mouse models of Alzheimer’s disease and multiple sclerosisJournal of NeuroinflammationFebruary 23, 2026Buxin Chen, Hsueh-Chung Lu, Lei Huang, Jean Wang, Matthew Bujold, Lingyun Tang, Xin Du, Yubin WangAntibody, clone 4G10 (Sigma-Aldrich, #05–321), DAP12 (D7G1X) Rabbit mAb (Cell Signaling Technology, #12492), or Mouse TREM2 Biotinylated Antibody (R&D Systems, #BAF1729) followed by HRP-conjugated secondary

(3) ACLY promotes NK cell effector function by regulating glycolysis and histone acetylationThe Journal of ImmunologyNovember 1, 2025Hyogon Sohn, Ana Kolicheski, Jennifer Poursine-Laurent, Jennifer Tran, Yongjun Wang, Kelly Gan, Joshua M. Tobin, Nermina Saucier, Todd A. Fehniger, Jacqueline E. Payton, et al.antibodies used for immunoblotting analysis were monoclonal rabbit anti-DAP12 (Cell Signaling Technology, 12492), mouse anti-DAP10 (Santa Cruz Biotechnology, sc-374196), β-actin monoclonal antibody (ThermoFisher,

(4) Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in miceNature neuroscienceAugust 1, 2024O'Shea TM, Ao Y, Wang S, Ren Y, Cheng AL, Kawaguchi R, Shi Z, Swarup V, Sofroniew MV.(1:800, 16644-1-AP; Proteintech), sheep anti-Trem2 (1:400, AF1729; Novus), rabbit anti-Tyrobp (1:400,12492S; Cell Signaling) and rat anti-Vim (1:200, MAB2105; Novus). All antibodies were sourced from commercial

(5) Protocol for gene knockdown using siRNA in primary cultured neonatal murine microgliaSTAR ProtocolsMarch 15, 2024Yuma Kato, Sho Takatori, Aika Akahori, Hayato Etani, Yung Ning Chu, Taisuke TomitaAB_2799888 "Rabbit monoclonal anti-DAP12 (D7G1X) (1:1,000 dilution)",Cell Signaling Technology,Cat#12492; RRID: AB_272112 Mouse monoclonal anti-SHIP1 (P1C1) (1:200 dilution),Santa Cruz Biotechnology,Cat#sc-8425;

(6) Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk PathwayMBioMay 7, 2019Liu Y, Li R, Chen XX, Zhi Y, Deng R, Zhou EM, Qiao S, Zhang G.9212), phospho-p38 MAPK (Thr180/Tyr182) antibody (catalog no. 9211), DAP12 (D7G1X) rabbit MAb (catalog no. 12492), and E-cadherin (24E10) rabbit MAb (catalog no. 3195) were all purchased from Cell Signaling Technology

(7) C-Type Lectin Receptor CD23 Is Required for Host Defense against Candida albicans and Aspergillus fumigatus InfectionJournal of immunology (Baltimore, Md. : 1950)October 15, 2018Guo Y, Chang Q, Cheng L, Xiong S, Jia X, Lin X, Zhao X.ERK (9101), phosphorylated JNK (9251), phosphorylated p38 (4631) and JNK (9252), p38 (9212), Dap12 (12492), SHP-1 (3759), SHP-2 (3397), and SHIP-1 (2726) were purchased from Cell Signaling Technology. Ab against FcRg

(8) Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric ImmunoreceptorsCancer immunology researchJuly 1, 2015Wang E, Wang LC, Tsai CY, Bhoj V, Gershenson Z, Moon E, Newick K, Sun J, Lo A, Baradet T, et al.Western blotting of protein lysates from the TILs described in panels C and D for DAP12 (clone D7G1X; #12492; Cell Signaling Technology) and β-actin (polyclonal; #AV52099; Sigma-Aldrich). (G) Western blotting

(9) The Membrane-Bound Mucins: How Large O-Glycoproteins Play Key Roles in Epithelial Cancers and Hold Promise as Biological Tools for Gene-Based and ImmunotherapiesCritical Reviewsâ„¢ in OncogenesisJanuary 1, 2008Nicolas Jonckheere, Isabelle Van SeuningenDF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion. J Biol Chem. 1997;272(19): 12492–4. H T U 30. Carraway KL, Ramsauer VP, Haq B, Carothers Carraway CA. Cell signaling through membrane

(10) TREM2 Is a Receptor for β-Amyloid that Mediates Microglial FunctionNeuronJanuary 1, 0001Zhao Y, Wu X, Li X, Jiang LL, Gui X, Liu Y, Sun Y, Zhu B, Piña-Crespo JC, Zhang M, et al.(clone A-9, sc-376087, Santa Cruz Biotechnology), rabbit monoclonal antibody against DAP12 (Clone D7G1X, 12492, Cell Signaling Technology) rabbit monoclonal antibody for phospho-SYK (clone F.724.5, MA5-14918, Thermo Fisher Scientific

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DAP12 (D7G1X) Rabbit mAb

DAP12 (D7G1X) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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DAP12 (D7G1X) Rabbit mAb from Cell Signaling Technology

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