LRRK2 (D18E12) Rabbit mAb 13046S from Cell Signaling Technology

Product Specs
ItemLRRK2 (D18E12) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number13046S
Quantity100 µl
ApplicationsW, W-S, IP
ReactivityH, M, R
TargetLRRK2
HostRabbit
NCBI Full Gene Nameleucine rich repeat kinase 2
NCBI Gene AliasesAURA17, DARDARIN, PARK8, RIPK7, ROCO2
ClonalityMonoclonal
Research AreaNeuroscience
IsotypeIgG
CloneD18E12
Molecular Weight290

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) miR-369-3p Modulates LRRK2-Mediated Inflammation and Autophagy in RAW264.7 MacrophagesInt J Mol SciApril 2, 2026Viviana Scalavino, Emanuele Piccinno, Ilaria Grassi, Raffaele Armentano, Gianluigi Giannelli, Grazia SerinoScientific, Waltham, MA, USA) according to the manufacturer’s protocol. The primary antibodies LRRK2 (#13046, Cell Signaling, Technology, Danvers, MA, USA, dilution 1:1000), LC3A/B (#12741, Cell Signaling, Technology,

(2) Targeting leucine-rich repeat kinase 2 overcomes resistance to oncolytic herpes simplex virus-based therapies in glioblastomaNature CommunicationsFebruary 28, 2026Yaning Qin, Zhiqi Liang, Mengqin Yu, Nanqian Lin, Naizhen Wang, Xuanke Huang, Shi Chen, Qun Peng, Yanhua Lin, Heqin Wang, et al.anti-Phospho-Rab10 (T73) (Abcam, ab230261, 1: 500, RRID: AB_2811274) anti-LRRK2 (Cell Signaling Technologies, 13046, 1: 200, RRID: AB_2798098), anti-GFAP (Sigma‒Aldrich, HPA056030, 1: 6000, RRID: AB_2683015), anti-Ki67

(3) CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegenerationScience advancesNovember 22, 2024Liu Q, Huang B, Guiberson NGL, Chen S, Zhu D, Ma G, Ma XM, Crittenden JR, Yu J, Graybiel AM, et al.N138/6, University of California Davis/NIH NeuroMab facility), rabbit monoclonal anti-LRRK2 (D18E12, #13046, Cell Signaling Technology), rabbit monoclonal anti-LRRK2 (c41-2, ab133474, Abcam), rabbit anti-TH polyclonal

(4) Sex-dependent interactions between prodromal intestinal inflammation and LRRK2 G2019S in mice promote endophenotypes of Parkinson's diseaseCommunications biologyMay 15, 2024Fang P, Yu LW, Espey H, Agirman G, Kazmi SA, Li K, Deng Y, Lee J, Hrncir H, Romero-Lopez A, et al.the following antibodies. Primary antibodies: rabbit anti-LRRK2 Antibody (D18E12) (Cell Signaling #13046), rabbit anti-phospho-LRRK2 (Ser935) Antibody (Cell Signaling #59576), rabbit anti-beta Actin monoclonal

(5) Characterization of Acetylation of Histone H3 at Lysine 9 in the Trigeminal Ganglion of a Rat Trigeminal Neuralgia ModelOxidative Medicine and Cellular LongevityMay 4, 2022Wenbin Wei, Yuemin Liu, Yating Qiu, Minjie Chen, Yiwen Wang, Zixiang Han, Ying Chaiharvested and mixed with 1 μg phosphoserine/threonine (Abcam, ab17464), HDAC3 (CST, #85057), LRRK2 (CST, #13046), or IgG Rabbit IgG antibody and 40 μl flurry IgA beads (Thermo Fisher Scientific) for rotating overnight

(6) Dopamine neuron-specific LRRK2 G2019S effects on gene expression revealed by translatome profilingNeurobiology of DiseaseJuly 1, 2021Judit Pallos, Sophia Jeng, Shannon McWeeney, Ian Martintransferred to nitrocellulose membranes. Blots were incubated with primary antibodies (anti-LRRK2 D18E12 (CST 13046), anti-GFP (Invitrogen G10362), anti-β-actin-HRP (Sigma A3854)) at 1:1000 for 18 h at 4°C and secondary

(7) Defects in mRNA Translation in LRRK2-Mutant hiPSC-Derived Dopaminergic Neurons Lead to Dysregulated Calcium HomeostasisCell stem cellOctober 1, 2020Kim JW, Yin X, Jhaldiyal A, Khan MR, Martin I, Xie Z, Perez-Rosello T, Kumar M, Abalde-Atristain L, Xu J, et al.chloroform). The following antibodies were used for western blots: α-LRRK2 (1:1000, Cell Signaling #13046), α-S6 (1:1000, Cell Signaling #2217), α-S15 and α-P-S15 (in house, previously published (Martin et

(8) Dietary Amino Acids Impact LRRK2-Induced Neurodegeneration in Parkinson's Disease ModelsThe Journal of NeuroscienceAugust 5, 2020Vinita G. Chittoor-Vinod, Steffany Villalobos-Cantor, Hanna Roshak, Kelsey Shea, Leire Abalde-Atristain, Ian Martincatalog #4967, Cell Signaling Technology); p-LRRK2 (1:750; catalog #ab203181, Abcam); LRRK2 (1:1000; catalog #13046, Cell Signaling Technology); Chittoor-Vinod et al. · Dietary Impact on Mutant LRRK2 Neurodegeneration RPS15

(9) Celastrol Inhibits Dopaminergic Neuronal Death of Parkinson's Disease through Activating MitophagyAntioxidants (Basel, Switzerland)December 31, 2019Lin MW, Lin CC, Chen YH, Yang HB, Hung SY.(Cell Signaling Technology, Danvers, MA, USA; 5933), anti-LRRK2 (Cell Signaling Technology, Danvers, MA, USA; 13046), anti-Ub (Santa Cruz Biotechnology, Dallas, TX, USA; sc-8017), or anti-EF-Tu (Santa Cruz Biotechnology,

(10) Genetic Deletion of Paired Immunoglobulin-Like Receptor B Does Not Promote Axonal Plasticity or Functional Recovery after Traumatic Brain InjuryJournal of NeuroscienceSeptember 29, 2010Shusaku Omoto, Masaki Ueno, Soichiro Mochio, Toshiyuki Takai, Toshihide Yamashitaaxonal remodeling and functional recovery after cortical injury. We focused on the newly sprout- 13046 • J. Neurosci., September 29, 2010 • 30(39):13045–13052 Omoto et al. • PirB and Axonal Plasticity ing

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LRRK2 (D18E12) Rabbit mAb

LRRK2 (D18E12) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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LRRK2 (D18E12) Rabbit mAb from Cell Signaling Technology

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