Caspase-7 (D2Q3L) Rabbit mAb 12827S from Cell Signaling Technology

Product Specs
ItemCaspase-7 (D2Q3L) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12827S
Quantity100 µl
ApplicationsW
ReactivityH, M, R
TargetCasp7
HostRabbit
NCBI Full Gene Namecaspase 7
NCBI Gene AliasesCASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
ClonalityMonoclonal
Research AreaApoptosis
CloneD2Q3L
IsotypeIgG
Molecular Weight20, 35

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Pan-cancer N-glycoproteomic atlas of patient-derived xenografts uncovers FAT2 as an actionable surface targetCell Reports MedicineFebruary 17, 2026Meinusha Govindarajan, Salvador Mejia-Guerrero, Shawn C. Chafe, Shahbaz Khan, Wei Shi, Matthew Waas, Martin A. Rossotti, Amanda Khoo, Lydia Y. Liu, Vladimir Ignatchenko, et al.9661; RRID:AB_2341188 Caspase-7 (D2Q3L) Rabbit monoclonal antibody,Cell Signaling Technology,Cat# 12827; RRID:AB_2687912 Cleaved Caspase-7 (Asp198) Rabbit polyclonal antibody,Cell Signaling Technology,Cat#

(2) Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancerInt J Mol MedFebruary 2, 2026Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, et al.caspase-3 (Cell Signaling Technology, Inc.; cat. no. 7148), -7 (Cell Signaling Technology, Inc.; cat. no. 12827) and -8 (Cell Signaling Technology, Inc.; cat. no. 4790), cleaved caspase-3 (Cell Signaling Technology,

(3) ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma GrowthAdvanced ScienceJanuary 1, 2026Qi‐tao Chen, Qiao‐ling Huang, Ming‐zhi Han, Xue‐hui Hong, De‐yi Feng, Lu‐ming Yao, Wen‐bin Hong, Yue Chen, Ya‐ying Huang, Hang‐zi Chen, et al.anti‐IL‐6 (#A27935) were purchased from ABclonal. Anti‐mouse IgG Alexa Fluor 488 (#4408), anti‐caspase‐7 (#12827), and anti‐cleaved caspase‐7 (Asp198) (#9491) antibodies were purchased from Cell Signaling Technology.

(4) The Microbial Bile Acid Metabolite 3-Oxo-LCA Inhibits Colorectal Cancer ProgressionCancer ResearchDecember 15, 2025Fei Sun, Ke Wang, Xingchen Dong, Henry Secaira-Morocho, Alisa Hui, Chunmiao Cai, Jonathan J. Sze, Brian Low, Shirsa Udgata, Cheri A. Pasch, et al.Caspase-3 (cat #14220, RRID:AB_2798429), cleaved Caspase-7 (cat #8438, RRID:AB_11178377), Caspase-7 (cat #12827, RRID:AB_2687912), BCL-2 (cat #3498S, RRID:AB_1903907), PARP (cat #9542, RRID:AB_2160739), cleaved PARP

(5) RIOK2 kinase regulates the translocation of the FADD–RIPK1–Caspase-8 complex to the ER and the cleavage of Gasdermin D to drive pyroptosisNature CommunicationsNovember 17, 2025Mingtong Ma, Fei Wang, Pengfei Cui, Yingying Zhang, Hanyu Ma, Yifan He, Yuanna Cheng, Jingping Huang, Jingxiang Wang, Xiangyang Wu, et al.#2367), Flag (#14793), cleaved Caspase-8 (#8592), Caspase-8 (#4927), Caspase-3 (#9665), Caspase-7 (#12827), RIPK1 (#3493), Phospho-RIPK1 (#31122) were from Cell Signaling Technology. Monoclonal anti-FADD antibody

(6) Inhibition of miR-4284 could reduce apoptosis and neuroinflammation by targeting APBA1/JAK1/STAT3 signaling in Alzheimer’s diseaseCell & BioscienceOctober 31, 2025Jiyun Choi, Jinsu Hwang, Dohee Kim, Eunjae Jang, Geupil Jang, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong, Sujeong Jang,Cell Signaling Technology,94296,1:1000 Pro-caspase 9,Cell Signaling Technology,9508,1:1000 Pro-caspase 7,Cell Signaling Technology,12827,1:1000 Pro-caspase 3,Cell Signaling Technology,14220,1:1000 NeuN,Sigma-Aldrich,MAB377,1:2000 NFH,Cell Signaling Technology

(7) miR-7704-Enriched Stem Cell-Derived Extracellular Vesicles Attenuate Hyperoxia-Induced Apoptosis and Oxidation in Lung Epithelial CellsCurrent Issues in Molecular BiologyOctober 28, 2025Yu-Hsun Chang, Kun-Chi Wu, Dah-Ching Dingcleaved-caspase 3 (Cell Signaling, cat. No. #9664, Danvers, MA, USA), caspase 7 (Cell Signaling, cat. No. #12827), cleaved-caspase 7 (Cell Signaling Technology, cat. No. #9491), caspase 8 (Proteintech, cat. No. 66093-1--Ig),

(8) Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activityCell Death DisOctober 6, 2025Kevin Berthenet, Serena Diazzi, Catherine Jamard, Kinga B. Stopa, Clara Gil, Stefan Dragan, Deborah Fanfone, Trang TM. Nguyen, Nathalie Al, Francois Virard, et al.CASP3 (Clinisciences, sc-56053; Cell Signaling, 9662S; Euromedex, GTX110543), CASP7 (Cell Signaling, 12827S), SP1 (Cell Signaling, 9389S), CORO1B (Thermo Fisher Scientific, CF501573), P-CORO1B (Euromedex, EC-CP2621),

(9) SNORD93 suppresses colorectal cancer progression by inducing G0/G1 arrest and apoptosisTranslational Cancer ResearchSeptember 30, 2025Yingzhi Xu, Mingzhen Cai, Jiaming Li, Huihui Wu, José María Sayagués, Tingjin Zheng, Zhishan ZhangNo. 4132P; CST), CDK9 (cat. No. 2316P; CST), caspase 3 (cat. No. 14220T; CST), caspase 7 (cat. No. 12827T; CST), caspase 8 (cat. No. 4790T; CST), Bim (cat. No. 2933P; CST), receptor-interacting protein (RIP)

(10) A novel miR-4536-3p inhibition ameliorates Alzheimer's disease by reducing Aβ accumulation and tau phosphorylationAlzheimers Res TherAugust 12, 2025Jiyun Choi, Dohee Kim, Haewon Jeong, Jinsu Hwang, Mahesh Ramalingam, Sujin Han, Hyong-Ho Cho, Byeong C. Kim, Han-Seong Jeong, Sujeong Jang,Cell Signaling Technology,94296,1:1000 Pro-caspase 9,Cell Signaling Technology,9508,1:1000 Pro-caspase 7,Cell Signaling Technology,12827,1:1000 Pro-caspase 3,Cell Signaling Technology,14220,1:1000 Pro-PARP,Cell Signaling Technology,9542,1:1000 NeuN,Sigma-Aldrich,MAB377,1:2000 NFH,Cell Signaling Technology

(11) A fibrin gel-loaded Gouqi-derived nanovesicle (GqDNV) repairs the heart after myocardial infarction by inhibiting p38 MAPK/NF-κB p65 pathwayJ NanobiotechnologyJuly 22, 2025Huan-Huan Zhou, Xiaolei Zhou, Jianqiu Pei, Shiyin Xu, Biyu Jin, Jiuling Chen, Zixuan Zhang, Mingmeng Tang, Yan Liu, Andreas K. Nüssler, et al.(AP1294, ABclonal), NF-κB p65 (A19653, ABclonal), Cleaved Caspase-7 (8438S, Cell signaling), Caspase-7 (12827S, Cell signaling), Cleaved Caspase-3 (9664S, Cell signaling), Caspase-3 (9662S, Cell signaling), Bax

(12) Isoliensinine Induces Ferroptosis in Urothelial Carcinoma Cells via the PI3K/AKT/HIF-1α Axis: Molecular Evidence from Next-Generation SequencingPharmaceuticals (Basel)July 6, 2025Yun-Chen Li, Hsuan-En Huang, Chia-Ying Yu, Ya-Chuan Chang, Shu-Yu Lin, Shao-Chuan Wang, Wen-Wei SungIL, USA), cleaved-caspase 3 (CST #9661, Cell Signaling Technology, Boston, MA, USA), caspase 7 (CST #12827, Cell Signaling Technology), cleaved-caspase 7 (CST #9491, Cell Signaling Technology), PARP (13371-1-AP,

(13) Therapeutic effects of miR-937-3p by targeting NTN1 expression and regulating apoptosis in an Aβ-induced neuronal cell deathSci RepJuly 2, 2025Jiyun Choi, Haewon Jeong, Mahesh Ramalingam, Jinsu Hwang, Seong-Jin Kim, Byeong C. Kim, Han-Seong Jeong, Sujeong Jang,Cell Signaling Technology,94296,1:1000 Pro-caspase-9,Cell Signaling Technology,9508,1:1000 Pro-caspase-7,Cell Signaling Technology,12827,1:1000 Pro-caspase-3,Cell Signaling Technology,14220,1:1000 Cleaved-caspase-3,Cell Signaling Technology,9664,1:500 Pro-PARP,Cell Signaling Technology

(14) C1QL1 inhibits breast cancer through the HSP90α/VCP-ERS/UPR axisExperimental & molecular medicineJune 1, 2025Zhang N, Shao Q, Xiang X, Yan C, Tao D, Li Q, Rong H, Zhao Y, Xiang T, Zeng X.anti-Bcl-2 (4223, CST), anti-Caspase 9 (9508, CST), anti-cleaved Caspase 9 (52873, CST), anti-Caspase 7 (12827, CST), anti-cleaved Caspase 7 (8438, CST), anti-Caspase 3 (14220, CST), anti-cleaved Caspase 3 (9664,

(15) Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumorCell Reports MedicineMay 20, 2025Patricia D.B. Tiburcio, Kenian Chen, Lin Xu, Kenneth S. ChenRRID:AB_1904178), GAPDH (Cell Signaling Technology 97166, RRID:AB_2756824), Caspase-7 (Cell Signaling Technology 12827, RRID:AB_2687912), cleaved Caspase-7 (Cell Signaling Technology 8438, RRID:AB_11178377; 1:1,000), Cyclin

(16) Anticancer effects of SH003 and its active component Cucurbitacin D on oral cancer cell lines via modulation of EMT and cell viabilityOncology ResearchApril 18, 2025HYEONG SIM CHOI, JEONG-KUI KU, SEONG-GYU KO, PIL-YOUNG YUNantibodies against caspase-3 (1:1000; Cell Signaling Technology, 9665, Danvers, MA, USA), 7 (1:1000; 12827), 9 (1:1000; Cell Signaling Technology, 9508), PARP (1:1000; Cell Signaling Technology, 9542), E-cadherin

(17) Pharmacological targeting of mitophagy via ALT001 improves herpes simplex virus 1 (HSV1)-mediated microglial inflammation and promotes amyloid β phagocytosis by restricting HSV1 infectionTheranosticsMarch 31, 2025Soo-Jin Oh, Young Yeon Kim, Ruiying Ma, Seok Tae Choi, Se Myeong Choi, Jong Hyun Cho, Ji-Yeun Hur, Yongjin Yoo, Kihoon Han, Hosun Park, et al.(SC-33641, Santa Cruz), Rab9 (5118, Cell Signaling Tech), PARP (9542, Cell Signaling Tech), Caspase 7 (12827, Cell Signaling Tech), Caspase 9 (9508, Cell Signaling Tech), and Caspase 3 (14220, Cell Signaling Tech).

(18) The gold complex auranofin sensitizes platinum resistant epithelial ovarian cancer cells to cisplatinBiochem Biophys RepMarch 29, 2025Farah H. Abdalbari, Benjamin N. Forgie, Edith Zorychta, Alicia A. Goyeneche, Abu Shadat M. Noman, Carlos M. TelleriaCell Signaling), monoclonal anti-caspase-9 (9508, Cell Signaling), and monoclonal anti-caspase-7 (D2Q3L1; 12827S, Cell Signaling). Secondary antibodies used were goat anti-rabbit IgG (H + L) HRP conjugate (1706515,

(19) USP7 V517F mutation as a mechanism of inhibitor resistanceNat CommunMarch 14, 2025Yu-Ling Miao, Fengying Fan, Yong-Jun Cheng, Li Jia, Shan-Shan Song, Xia-Juan Huan, Xu-Bin Bao, Jian Ding, Xuekui Yu, Jin-Xue HeRad18 (#9040); DNMT1 (#5032); UHRF1 (#12387); caspase-3 (#9662); cleaved caspase-3 (#9661); caspase-7 (#12827); cleaved caspase-7 (#8438); PARP1 (#9542). Antibody against p53 (#sc-126) was purchased from Santa Cruz Biotechnology

(20) Targeting sphingosine kinase 1 in p53KO thymic lymphomaThe FASEB JournalJanuary 11, 2025Fabiola N. Velazquez, Jeffrey L. Stith, Leiqing Zhang, Amira M. Allam, John Haley, Lina M. Obeid, Ashley J. Snider, Yusuf A. HannunCell Signaling Technology), caspase 8 (1:1000, Cat#4790, Cell Signaling Technology), caspase 7 (1:1000, Cat#12827, Cell Signaling Technology), caspase 9 (1:1000, Cat#95020, Cell Signaling Technology), p16 (1:1000,

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Caspase-7 (D2Q3L) Rabbit mAb

Caspase-7 (D2Q3L) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Caspase-7 (D2Q3L) Rabbit mAb from Cell Signaling Technology

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