MetAP2 (D3I1H) Rabbit mAb 12547S from Cell Signaling Technology

Product Specs
ItemMetAP2 (D3I1H) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12547S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
TargetMetAP2
HostRabbit
NCBI Full Gene Namemethionyl aminopeptidase 2
NCBI Gene AliasesMAP2, MNPEP, p67eIF2
ClonalityMonoclonal
Research AreaTranslational Control
CloneD3I1H
IsotypeIgG
Molecular Weight63

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cellsTheranosticsMay 16, 2022Lena Hölzen, Jan Mitschke, Claudia Schönichen, Maria Elena Hess, Sophia Ehrenfeld, Melanie Boerries, Cornelius Miething, Tilman Brummer, Thomas Reinheckelmouse,1:500,2103S; Cell signaling Metap1; rabbit,1:1000,A305584A-M; Thermo fisher Metap2; rabbit,1:1000,12547; Cell signaling S6 ribosomal protein; mouse,1:1000,2317S; Cell signaling pS6 Ribosomal Protein (Ser235/236);

(2) Methionine aminopeptidase‑2 is a pivotal regulator of vasculogenic mimicryOncology ReportsDecember 15, 2021Shota Shimizu, Ryota Kawahara, Siro Simizuµg/lane) were transferred to polyvinylidene fluoride membranes and immunoblotted with anti-MetAP2 (#12547S; Cell Signaling Technology, Inc.) or anti-α-tubulin (#T5168; Merck KGaA). Signals were detected by ECL

(3) Telomere Replication: Solving Multiple End Replication ProblemsFrontiers in Cell and Developmental BiologyApril 1, 2021Erin Bonnell, Emeline Pasquier, Raymund J. Wellinger(2010). Evolution of CST function in telomere maintenance. Cell Cycle 9, 3177–3185. doi: 10.4161/cc.9.16.12547 Prioleau, M. N., and MacAlpine, D. M. (2016). DNA replication origins—Where do we begin? Genes Dev.

(4) Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusionseLifeAugust 5, 2020Zhi-Jing Wu, Jia-Cheng Liu, Xin Man, Xin Gu, Ting-Yi Li, Chen Cai, Ming-Hong He, Yangyang Shao, Ning Lu, Xiaoli Xue, et al.CST function in telomere maintenance. Cell Cycle 9:3177–3185. DOI: https://doi.org/10.4161/cc.9.16.12547 Puglisi A, Bianchi A, Lemmens L, Damay P, Shore D. 2008. Distinct roles for yeast Stn1 in telomere capping

(5) Getting to grips with circular chromosomeseLifeAugust 5, 2020Constance Nugent, Katsunori SugimotoCST function in telomere maintenance. Cell Cycle 9:3177–3185. DOI: https://doi.org/10.4161/cc.9.16.12547 Pristyazhnyuk IE, Menzorov AG. 2018. Ring chromosomes: from formation to clinical potential. Protoplasma

(6) 53BP1: a DSB escortGenes & DevelopmentJanuary 4, 2020Zachary Mirman, Titia de Lange2010. Evolution of CST function in telomere maintenance. Cell Cycle 9: 3157–3165. doi:10.4161/cc.9.16.12547 Ray Chaudhuri A, Nussenzweig A. 2017. The multifaceted roles of PARP1 in DNA repair and chromatin remodelling.

(7) Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLCeLifeNovember 19, 2019Zeng H, Castillo-Cabrera J, Manser M, Lu B, Yang Z, Strande V, Begue D, Zamponi R, Qiu S, Sigoillot F, et al.anti-GNAQ (#14373, 1:1,000), anti-HSP90 (#4877, 1:5,000), anti-ALDOA (#8060, 1:5,000), anti-METAP2 (#12547, 1:1,000), anti-GAPDH (#2118, 1:5,000), anti-RHOA (#2117, 1:1,000), anti-Cofilin (#5175, 1:1,000), anti-phospho-Cofilin (Ser3

(8) Comprehensive comparison of MetAP2 tissue and cellular expression pattern in lean and obese rodentsDiabetes, Metabolic Syndrome and Obesity: Targets and TherapyOctober 16, 2018Jing Han, Yang Tang, Mingjian Lu, Haiqing Hua30 minutes at room temperature. Then, the slices were incubated with 200 µL of primary antibody (CST, #12547) diluted in Dako diluent (#S0809) for 2 hours at room temperature. Subsequently, the slices were washed

(9) Understanding diversity in telomere dynamicsPhilosophical Transactions of the Royal Society B: Biological SciencesMarch 5, 2018Pat Monaghan, Dan T. A. Eisenberg, Lea Harrington, Dan Nussey2010 Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. (doi:10.4161/cc.9.16.12547) Ishikawa F, Naito T. 1999 Why do we have linear chromosomes? A matter of Adam and Eve. Mutat. Res.

(10) A Matter of Scale and Dimensions: Chromatin of Chromosome Landmarks in the FungiMicrobiology SpectrumAugust 25, 2017Allyson A. Erlendson, Steven Friedman, Michael FreitagBeilstein MA, Shippen DE. Evolution of CST function in telomere maintenance. Cell Cycle. 2010; 9:3157–65. 12547 [pii]. DOI: 10.4161/cc. 9.16.12547 [PubMed: 20697207] 83. Kothe GO, Kitamura M, Masutani M, Selker EU,

(11) Telomere recombination pathways: tales of several unhappy marriagesCurrent GeneticsJune 1, 2017Neal F. Lue, Eun Young YuShippen DE. Evolution of CST function in telomere maintenance. Cell Cycle. 2010; 9:3157–3165. doi: 12547 10.4161/cc.9.16.12547. [PubMed: 20697207] Shay JW, Reddel RR, Wright WE. Cancer. Cancer and telomeres--an

(12) Ubiquitination and SUMOylation in Telomere Maintenance and DysfunctionFrontiers in GeneticsMay 23, 2017Zeliha YalÃ§in, Carolin Selenz, Jacqueline J. L. Jacobs(2010). Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. doi: 10.4161/cc.9.16.12547 Rai, R., Chen, Y., Lei, M., and Chang, S. (2016). TRF2-RAP1 is required to protect telomeres from engaging

(13) The mre11 A470 alleles influence the hereditability and the segregation of telosomes in Saccharomyces cerevisiaePloS oneJanuary 1, 2017Baek IJ, Moss DS, Lustig AJ.in telomere maintenance. Cell Cycle. 2010; 9(16):3157–65. Epub 2010/08/11. https://doi.org/10.4161/cc. 9.16.12547 PMID: 20697207. 7. Lamarche BJ, Orazio NI, Weitzman MD. The MRN complex in double-strand break repair

(14) MTV, an ssDNA Protecting Complex Essential for Transposon-Based Telomere Maintenance in DrosophilaPLOS GeneticsNovember 11, 2016Yi Zhang, Liang Zhang, Xiaona Tang, Shilpa R. Bhardwaj, Jingyun Ji, Yikang S. RongEvolution of CST function in telomere maintenance. Cell Cycle. 2010; 9: 3157–3165. doi: 10.4161/cc.9.16.12547 PMID: 20697207 11. Zhang L, Beaucher M, Cheng Y, Rong YS. Coordination of transposon expression with

(15) STN1 OB Fold Mutation Alters DNA Binding and Affects Selective Aspects of CST FunctionPLOS GeneticsSeptember 30, 2016Anukana Bhattacharjee, Jason Stewart, Mary Chaiken, Carolyn M. Price(2010) Evolution of CST function in telomere maintenance. Cell Cycle 9: 3157â€"3165. doi: 10.4161/cc.9.16.12547 PMID: 20697207 38. Qi H, Zakian VA (2000) The Saccharomyces telomere-binding protein Cdc13p interacts

(16) Telomere- and Telomerase-Associated Proteins and Their Functions in the Plant CellFrontiers in Plant ScienceJune 28, 2016Petra ProchÃ¡zkovÃ¡ SchrumpfovÃ¡, Å Ã¡rka SchoÅ™ovÃ¡, JiÅ™Ã Fajkus(2010). Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. doi: 10.4161/cc.9.16.12547 Price, C. M., and Cech, T. R. (1987). Telomeric DNA-protein interactions of Oxytricha macronuclear DNA.

(17) Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding ProteinsFrontiers in GeneticsFebruary 10, 2016Arthur J. Lustig(2010). Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. doi: 10.4161/cc.9.16.12547 Ribeyre, C., and Shore, D. (2012). Anticheckpoint pathways at telomeres in yeast. Nat. Struct. Mol.

(18) Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactionsScienceOctober 30, 2015Jiansen Jiang et al.Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165 (2010). doi: 10.4161/ cc.9.16.12547; pmid: 20697207 20. P. Wu, H. Takai, T. de Lange, Telomeric 3′ overhangs derive from resection by Exo1

(19) Telomere DNA recognition in Saccharomycotina yeast: potential lessons for the co-evolution of ssDNA and dsDNA-binding proteins and their target sitesFrontiers in GeneticsMay 1, 2015Olga Steinberg-Neifach, Neal F. Lue(2010). Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. doi: 10.4161/cc.9.16.12547 Qi, H., and Zakian, V. A. (2000). The Saccharomyces telomere-binding protein Cdc13p interacts with both

(20) Signaling of double strand breaks and deprotected telomeres in ArabidopsisFrontiers in Plant ScienceOctober 16, 2013Simon Amiard, Maria E. Gallego, Charles I. WhiteE. (2010). Evolution of CST function in telomere maintenance. Cell Cycle 9, 3157–3165. doi: 10. 4161/cc.9.16.12547 Redon, C., Pilch, D. R., Rogakou, E. P., Orr, A. H., Lowndes, N. F., and Bonner, W. M. (2003). Yeast

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MetAP2 (D3I1H) Rabbit mAb

MetAP2 (D3I1H) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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MetAP2 (D3I1H) Rabbit mAb from Cell Signaling Technology

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