SirT2 (D4S6J) Rabbit mAb 12672S from Cell Signaling Technology

Product Specs
ItemSirT2 (D4S6J) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12672S
ApplicationsWestern Blot (WB)
ReactivityHu, Ms, Rt, Mk
Research AreaChromatin Regulation / Nuclear Function
CloneD4S6J
Molecular Weight39, 43
ClonalityMonoclonal
NCBI Gene AliasesSIR2, SIR2L, SIR2L2
NCBI Full Gene Namesirtuin 2
HostRabbit
TargetSirT2
Quantity100 µl

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart RegenerationCirculationJanuary 7, 2025Shijie Liu, Vaibhav Deshmukh, Fansen Meng, Yidan Wang, Yuka Morikawa, Jeffrey D. Steimle, Rich Gang Li, Jun Wang, James F. MartinAbcam, Cambridge, UK), rabbit anti-SIRT1 (1:1000, #9475, Cell Signaling), rabbit anti-SIRT2 (1:1000, 12672, Cell Signaling), rabbit anti-TUBA4A (1:1000, ab228701, Abcam), mouse anti-TUBA4A (1:1000, T5168, Sigma-Aldrich),

(2) Proximity‐dependent biotinylation reveals an interaction between ubiquitin‐specific peptidase 46 and centrosome‐related proteinsFEBS Open BioOctober 31, 2024Kazuma Yoshioka, Reiko Nakagawa, Chi Lieu Kim Nguyen, Hayate Suzuki, Kiyohiro Ishigaki, Seiya Mizuno, Tsukasa Okiyoneda, Shizufumi Ebihara, Kazuya MurataRosemont, IL, USA), anti‐green fluorescent protein (GFP) (50 430‐2‐AP; 1:2000, Proteintech), anti‐SIRT2 (#12672; 1:200, Cell Signaling Technology), anti‐SNAP29 (#EPR9199; 1:1000, Abcam, Cambridge, UK), anti‐HAP1

(3) Roles of Growth Hormone–Dependent JAK-STAT5 and Lyn Kinase Signaling in Determining Lifespan and Cancer IncidenceEndocrinologyOctober 8, 2024Yash Chhabra, Helle Bielefeldt-Ohmann, Tania Louise Brooks, Andrew James Brooks, Michael J WatersAntibody,ab110413,AB 2629281,Abcam SIRT1 (DID7),9475,AB 2617130,Cell Signaling Technology SIRT2 (D4S6J),12672,AB 2636961,Cell Signaling Technology SIRT3 (D22A3),5490,AB 10696895,Cell Signaling Technology SIRT6

(4) Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty ArthritisJournal of Innate ImmunityJune 29, 2023Qingsong Zhao, Nan Xia, Jinmei Xu, Yingnan Wang, Luwen Feng, Dihan Su, Zhifeng Chenganti-pro-IL-1β (12703, 1:1,000, CST), rabbit anti-cleaved IL-1β (83186, 1:1,000, CST), rabbit anti-SIRT2 (12672, 1:1,000, CST), rabbit anti-pro-caspase-1 (3866, 1:1,000, CST), rabbit anti-NLRP3 (15101, 1:1,000, CST),

(5) SIRT5 Is the Desuccinylase of LDHA as Novel Cancer Metastatic Stimulator in Aggressive Prostate CancerGenomics, Proteomics & BioinformaticsFebruary 1, 2023Oh Kwang Kwon, In Hyuk Bang, So Young Choi, Ju Mi Jeon, Ann-Yae Na, Yan Gao, Sam Seok Cho, Sung Hwan Ki, Youngshik Choe, Jun Nyung Lee, et al.against SIRT1 (Catalog No. 8469S, Cell Signaling Technology Technology, Beverly, MA), SIRT2 (Catalog No. 12672S, Cell Signaling Technology), SIRT3 (Catalog No. 5490S, Cell Signaling Technology), SIRT4 (Catalog No.

(6) SIRT3 inhibitor 3-TYP exacerbates thioacetamide-induced hepatic injury in miceFrontiers in physiologyJanuary 1, 2022Shi C, Jiao F, Wang Y, Chen Q, Wang L, Gong Z.(#13435), HO-1 (#43966), Cleaved caspase 3 (#9664), TNF-α (#11948), IL-1β (#12426), SIRT1 (#8469), SIRT2 (#12672), SIRT3 (#5490), MnSOD (#13194), and GAPDH (# 5174) were obtained from Cell Signaling Technology (CST)

(7) The selective degradation of sirtuins via macroautophagy in the MPP⁺ model of Parkinson's disease is promoted by conserved oxidation sitesCell death discoveryOctober 12, 2021Baeken MW, Schwarz M, Kern A, Moosmann B, Hajieva P, Behl C.Sigma-Aldrich unless stated otherwise. Used primary antibodies included: anti-SIRT1 (9475, CST); anti-SIRT2 (12672, CST); anti-SIRT3 (2627, CST); anti-SIRT4 (NB100-1406, Novus Biologicals); anti-SIRT5 (8782, CST); anti-SIRT6

(8) A redox-mediated conformational change in NQO1 controls binding to microtubules and α-tubulin acetylationRedox biologyFebruary 1, 2021Siegel D, Bersie S, Harris P, Di Francesco A, Armstrong M, Reisdorph N, Bernier M, de Cabo R, Fritz K, Ross D.from Sigma-Aldrich. 2.3 Antibodies Rabbit anti-acetyl α-tubulin (K40, #5335), rabbit anti-SIRT2 (#12672) and mouse anti-α tubulin (#3873) were obtained from Cell Signaling Technology (Danvers, MA). Mouse

(9) Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 ReceptorInternational journal of molecular sciencesOctober 22, 2020Okuyama T, Shirakawa J, Tajima K, Ino Y, Vethe H, Togashi Y, Kyohara M, Inoue R, Miyashita D, Li J, et al.AB_10902083, 1/600), Sirt1 (Abcam, ab110304, RRID: AB_10864359, 1/1000), Sirt2 (Cell Signaling Technology #12672, RRID: AB_2636961, 1/1000), phospho AMPKα (Thr172) (Cell Signaling Technology #2535, RRID: AB_331250,

(10) SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repairThe Journal of clinical investigationJune 1, 2020Zhang M, Du W, Acklin S, Jin S, Xia F.by SDS-PAGE. Antibodies used for immunoblotting were anti-SIRT2 (Cell Signaling Technology, catalog 12672S; Thermo Fisher, catalog PA5-20487; Proteintech, 19655-1-AP; 1:500), anti-Sirt1 (Cell Signaling Technology,

(11) Illuminating NAD⁺ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent SensorDevelopmental cellApril 20, 2020Zou Y, Wang A, Huang L, Zhu X, Hu Q, Zhang Y, Chen X, Li F, Wang Q, Wang H, et al.(sc-47778), and GAPDH (sc-365062) (Santa Cruz Biotechnologies); iNOS (#13120), SIRT1 (#9475), and SIRT2 (#12672) (Cell Signaling Technology); and MTHFD1 (10794–1-AP) (Proteintech), followed by secondary antibodies

(12) Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent DiseaseCell metabolismJune 4, 2019Amano H, Chaudhury A, Rodriguez-Aguayo C, Lu L, Akhanov V, Catic A, Popov YV, Verdin E, Johnson H, Stossi F, et al.,EMD Millipore,"Cat# 07-131, RRID:AB_10067921" "Rabbit monoclonal anti-SirT2 (D4S6J), 1:1000",Cell Signaling,"Cat# 12672, RRID: AB_2636961" "Rabbit monoclonal anti-SirT3 (D22A3), 1:1000",Cell Signaling,"Cat# 5490S, RRID:AB_10828246" "Rabbit

(13) Nanog Signaling Mediates Radioresistance in ALDH-Positive Breast Cancer CellsInternational Journal of Molecular SciencesMarch 6, 2019Mozhgan Dehghan Harati, H. Peter Rodemann, Mahmoud ToulanyAntibodies against P-Akt (Ser-473) (cat. # 4060), Akt1 (cat. # 2967), Nanog (cat. # 3580), Sirt2 (cat. # 12672), Notch1 Int. J. Mol. Sci. 2019, 20, 1151 10 of 14 (cat. # 3608), BMI1 (cat. # 5856), Oct-4 (cat.

(14) MicroRNA-140-5p aggravates hypertension and oxidative stress of atherosclerosis via targeting Nrf2 and Sirt2International Journal of Molecular MedicineNovember 26, 2018Qing‑Quan Liu, Ke Ren, Su‑Hong Liu, Wei‑Min Li, Chang‑Jun Huang, Xiu‑Hui Yang(cat. no. 12721; 1:2,000; Cell Signaling Technology, Inc., Danvers, MA, USA), anti-Sirt2 (cat. no. 12672; 1:2,000; Cell Signaling Technology, Inc.) and anti-GAPDH (cat. no. 5174; 1:50,000; Cell Signaling Technology,

(15) Tenovin-6 inhibits proliferation and survival of diffuse large B-cell lymphoma cells by blocking autophagyOncotargetFebruary 28, 2017Yuan H, He M, Cheng F, Bai R, da Silva SR, Aguiar RC, Gao SJ.Cell Signaling Technology), c-caspase 9 (SC-7885, Santa Cruz), SIRT1 (#8469, Cell Signaling Technology), SIRT2 (#12672, Cell Signaling Technology), SIRT3 (#2627, Cell Signaling Technology), SIRT4 (NB100-1406, Novus, St

(16) Tenovin-6 impairs autophagy by inhibiting autophagic fluxCell death & diseaseFebruary 9, 2017Yuan H, Tan B, Gao SJ.(#2524, CST), acetyl-p53 (K379) (#2570, CST), phospho-p53 (S15) (#9284, CST), SIRT1 (#8469, CST), SIRT2 (#12672, CST), Bax (#2772, CST), Puma (#4976, CST), p21 (#556430, BD Biosciences, Franklin Lakes, NJ, USA),

(17) NMDAR dependent intracellular responses associated with cocaine conditioned place preference behaviorBehavioural brain researchJanuary 15, 2017Nygard SK, Klambatsen A, Balouch B, Quinones-Jenab V, Jenab S.Chemical Co. (St. Louis, MO). Primary antibodies for pERK (9101), ERK (9102), SIRT1 (2493), SIRT2 (12672), FosB (5G4) and CREB (9197) were purchased from Cell Signaling Technologies (Beverly, MA). The primary

(18) SIRT2 enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced nigrostriatal damage via apoptotic pathwayFrontiers in Aging NeuroscienceAugust 11, 2014Lei Liu, Anirudh Arun, Lakia Ellis, Carina Peritore, Gizem Donmezsupernatant was loaded onto 4–15% gradient SDS-PAGE gels and immunoblotted with anti-SIRT2 (Cell signaling-12672, conc. 1:1000), Foxo3a (Abcam-ab47409, conc. 1:1000), Bim (Abcam-ab7888, conc. 1:1000), actin (Millipore-MAB1501,

Be the First to Write a Review!

SirT2 (D4S6J) Rabbit mAb

SirT2 (D4S6J) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (18)

Reviews

SirT2 (D4S6J) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map