FGF Receptor 2 (D4H9) Rabbit mAb 11835S from Cell Signaling Technology

Product Specs
ItemFGF Receptor 2 (D4H9) Rabbit mAb
CompanyCell Signaling Technology
Price $399.00 Inquire
Catalog Number11835S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetFGFR2
HostRabbit
NCBI Full Gene Namefibroblast growth factor receptor 2
NCBI Gene AliasesBBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
ClonalityMonoclonal
Research AreaRTK
IsotypeIgG
CloneD4H9
Molecular Weight92, 145

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Integrative Multi‐Omics Approaches Reveal Selectivity Profiles and Molecular Mechanisms of FIIN‐2, a Covalent FGFR InhibitorAdvanced ScienceFebruary 20, 2025Ying Fu, Dandan Zhu, Xiaojuan Chen, Lingzhi Qu, Ming Guo, Shuhong Zhang, Guangyu Xu, Zhuchu Chen, Maoyu Li, Yongheng ChenBiotechnology, YT2913), p‐mTOR (Ser2448) (Immunoway Biotechnology, YP0176), FGFR2 (Cell Signaling Technology, 11835), Src (Cell Signaling Technology, 2109), LC3 (Proteintech, 14600‐1‐AP), P62 (Proteintech, 18420‐1‐AP),

(2) Synergic activity of FGFR2 and MEK inhibitors in the treatment of FGFR2-amplified cancers of unknown primaryMolecular TherapyOctober 2, 2024Andrea Cavazzoni, Irene Salamon, Claudia Fumarola, Giulia Gallerani, Noemi Laprovitera, Francesco Gelsomino, Mattia Riefolo, Karim Rihawi, Elisa Porcellini, Tania Rossi, et al.protein analysis by western blotting are described elsewhere.63 Antibodies against p-FGFR (#3471), FGFR2 (#11835), p-ERK1/2Thr202/Tyr204 (#4370), ERK1/2 (#4695), p-AKTSer473 (#9271), AKT (#9272), p-P70S6KThr389 (#9205),

(3) Proteome‐based molecular subtyping and therapeutic target prediction in gastric cancerMolecular OncologyJune 1, 2024Changyuan Hu, Jiangning Song, Terry Kwok, Elizabeth V. Nguyen, Xian Shen, Roger J. Daly(cat. 2775s), CDK12 (cat. 11973s), ERBB2 (cat. 2165s), Phospho‐ERBB2 (Tyr877) (cat. 2241s), FGFR2 (cat. 11835s), Phospho‐FGFR (Tyr653/654) (cat. 3471s), Phospho‐Src Family (Tyr416) (cat. 2101s), Phospho‐mTOR (Ser2448)

(4) Convergent MAPK pathway alterations mediate acquired resistance to FGFR inhibitors in FGFR2 fusion-positive cholangiocarcinomaJournal of HepatologyFebruary 1, 2024Timothy P. DiPeri, Ming Zhao, Kurt W. Evans, Kaushik Varadarajan, Tyler Moss, Stephen Scott, Michael P. Kahle, Charnel C. Byrnes, Huiqin Chen, Sunyoung S. Lee, et al.(TAS-120) and infigratinib (BGJ-398) were purchased from SellckChem. Antibodies including anti-FGFR2 (#11835), anti-RAS_G12D (#14429), anti-phospho-AKT/S473 (#4060), anti-AKT (#9272), anti-phospho-ERK1/2/T202/Y204

(5) Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancerFrontiers in OncologyJanuary 12, 2024Delfina Popiel, Aleksandra Stańczak, Monika Skupińska, Agata Mikołajczyk, Paulina Stańczak, Filip Mituła, Joanna Hucz-Kalitowska, Kinga Jastrzębska, Damian Smuga, Jakub Dominowski, et al.analysis was performed using the following primary antibodies: anti-FGFR1 (D8E4, #9740), FGFR2 (D4H9; #11835), FGFR3 (C51F2, #4574S), anti-ERK (p44/42 MAPK (Erk1/2), #9102), and anti-pERK (p44/42 MAPK, #4370).

(6) Multiple receptor tyrosine kinases regulate dengue infection of hepatocytesFrontiers in cellular and infection microbiologyJanuary 1, 2024Bourgeois NM, Wei L, Ho NNT, Neal ML, Seferos D, Tongogara T, Mast FD, Aitchison JD, Kaushansky A.#sc-100299), EphB4 (GeneTex #GTX108595), ErbB2 (Cell Signaling Technology, Inc. (CST) # 2165), FGFR2 (CST #11835), IGF-1R (R&D Systems #MAB391) and RET (CST #3220) were used at a concentration of 1:100 then stained

(7) Receptor clustering by a precise set of extracellular galectins initiates FGFR signalingCellular and molecular life sciences : CMLSApril 3, 2023Zukowska D, Gedaj A, Porebska N, Pozniak M, Krzyscik M, Czyrek A, Krowarsch D, Zakrzewska M, Otlewski J, Opalinski L.and methods Antibodies and reagents The primary antibodies directed against FGFR1 (#9740), FGFR2 (#11835), FGFR3 (#4574), phospho-FGFR1 (pFGFR1; #3476), ERK1/2 (#9102), and phospho-ERK1/2 (pERK1/2; #9101)

(8) Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradationScientific reportsDecember 22, 2022Petit I, Levy A, Estrach S, Féral CC, Trentin AG, Dingli F, Loew D, Qu J, Zhou H, Théry C, et al.Santa Cruz Biotechnology), glypican-1 (#226855, 1:1000, Abcam) and FGFR1, FGFR2 and FGFR3 (#9740, #11835 and #4574 respectively, 1:1000, Cell Signaling Technology). Secondary antibodies (Cell signaling Technology)

(9) Truncated FGFR2 is a clinically actionable oncogene in multiple cancersNatureAugust 18, 2022Daniel Zingg et al.BD Biosciences), each for 30 min at 4 °C. Cells were incubated with primary antibodies (anti-FGFR2, 1:200, 11835, Cell Signaling Technology; anti-GFP, 1:200, ab6673, Abcam) overnight and subsequently with secondary

(10) Mother and Daughter Carrying of the Same Pathogenic Variant in FGFR2 with Discordant PhenotypeGenes (Basel)June 27, 2022Filomena Lo Vecchio et al.antibodies were used at the following concentrations: 1:1000 against-FGFR2 rabbit monoclonal antibody (#11835, Cell Signaling Technology, Danvers, MA, USA) and 1:25,000 against-GAPDH rabbit antibody (Abcam, Cambridge,

(11) STAT3 inhibition suppresses adaptive survival of ALK-rearranged lung cancer cells through transcriptional modulation of apoptosisNPJ precision oncologyFebruary 28, 2022Yanagimura N, Takeuchi S, Fukuda K, Arai S, Tanimoto A, Nishiyama A, Ogo N, Takahashi H, Asai A, Watanabe S, et al.AKT (#9272), BCL-XL (#2764), cleaved caspase-3 (#9664), cleaved PARP (#5625), FGFR1 (#9740), FGFR2 (#11835), FGFR3 (#4574), FGFR4 (#8562), MET (#8198), JAK1 (#3344), JAK2 (#3230), Tyk2 (#9312), gp130 (#3732),

(12) Nuclear Localization Sequence of FGF1 Is Not Required for Its Intracellular Anti-Apoptotic Activity in Differentiated CellsCellsFebruary 2, 2022Lampart A, Sluzalska KD, Czyrek A, Szerszen A, Otlewski J, Wiedlocha A, Zakrzewska M.rabbit anti-ERK1/2 (9102), rabbit anti-FGFR1 (9740), rabbit anti-FGF1 (3139), and rabbit anti-FGFR2 (11835) from Cell Signaling Technology (Danveres, MA, USA); goat anti-FGF1 (AF232) from R&D Systems (Minneapolis,

(13) Integrated chromatin and transcriptomic profiling of patient-derived colon cancer organoids identifies personalized drug targets to overcome oxaliplatin resistanceGenes & diseasesMarch 1, 2021Tung KL, Chen KY, Negrete M, Chen T, Safi A, Aljamal AA, Song L, Crawford GE, Ding S, Hsu DS, et al.Trans-Blot® Turbo™ Transfer System. The following primary antibodies and dilutions were used: FGFR1 (#9740), FGFR2 (#11835), pFGFR (#3471), β-Tubulin (#2128) antibodies (Cell Signaling Technology), OXTR (Abcam) and FGFR3 (sc-390423),

(14) Zotatifin, an eIF4A-Selective Inhibitor, Blocks Tumor Growth in Receptor Tyrosine Kinase Driven TumorsFrontiers in oncologyJanuary 1, 2021Gerson-Gurwitz A, Young NP, Goel VK, Eam B, Stumpf CR, Chen J, Fish S, Barrera M, Sung E, Staunton J, et al.CST#3700; Beta tubulin CST#86298; PRAS40 CST#2691; p-PRAS40 T246 CST#13175; ER alpha CST#8644; FGFR2 CST#11835; HER3 #12708; p-HER3 #2842; FoxO3a #2497; p-FoxO1 (T24)/FoxO3a (T32) #9464 (Cell Signaling Technology,

(15) Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the MAPK PathwayCancer ResearchNovember 1, 2020Yuhong Lu, Yanfeng Liu, Sebastian Oeck, Gary J. Zhang, Alexander Schramm, Peter M. GlazerCell Signaling), anti-ZEB-1 (#NBP 1-0-5987, Novus Bio), anti-FGFR1(#9740s, Cell Signaling), antiFGFR2 (#11835s, Cell Signaling), anti-FGFR3 (#4574s, Cell Signaling), anti-p44/42 MAPK (ERK1/2) (#9107s, Cell Signaling),

(16) Development of a precision medicine pipeline to identify personalized treatments for colorectal cancerBMC cancerJune 24, 2020Altunel E, Roghani RS, Chen KY, Kim SY, McCall S, Ware KE, Shen X, Somarelli JA, Hsu DS.membrane imaging. The following primary antibodies and dilutions were used: FGFR1 (#9740), FGFR2 (#11835), pFGFR (#3471), pSRC (#2105), pVEGFR (#12599), pERK (#4377), pAkt (#4060), pSTAT5 (#4322), pSTAT3(#9131),

(17) FGFR inhibition enhances sensitivity to radiation in non-small cell lung cancer.Molecular Cancer TherapeuticsJune 1, 2020Gopika SenthilKumar et al.Signaling Technology Cell Signaling Technology Cell Signaling Technology Cell Signaling Technology 9740 11835 4574 97166 4060 9718 Rabbit Cell Signaling Technology 4370 Mouse Cell Signaling Technology 4696 1:1000 1:1000 1:1000 1:10000 1:1000 In vitro

(18) Gain of FGF4 is a frequent event in KIT/PDGFRA/SDH/RAS-P WT GISTGenes, chromosomes & cancerSeptember 1, 2019Urbini M, Indio V, Tarantino G, Ravegnini G, Angelini S, Nannini M, Saponara M, Santini D, Ceccarelli C, Fiorentino M, et al.following primary antibodies were used: FGFR1 (#9740, Cell Signaling, Leiden, the Netherlands), FGFR2 (#11835, Cell Signaling), FGF4 (PA5‐52804, Thermo Fisher Scientific), phospho‐AKT (#9271, Cell Signaling), Phospho‐c‐KIT

(19) A functional CRISPR/Cas9 screen identifies kinases that modulate FGFR inhibitor response in gastric cancerOncogenesisMay 10, 2019Chen J, Bell J, Lau BT, Whittaker T, Stapleton D, Ji HP.Overexpression of FGFR2 was detected in KatoIII, SNU16, YCC28, and YCC30 cells by western blot. FGFR2 (#11835) and GAPDH (#5174) antibodies were purchased from Cell Signaling. Gastric cancer cell lines KatoIII

(20) Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine KinasesJournal of Pharmacology and Experimental TherapeuticsMarch 1, 2018Frank Hilberg et al.(cat. no.. 9665); FGF receptor 1 (D8E4) XP Rabbit mAb (cat. no. 9740); FGF receptor 2 (D4H9) (cat. no. 11835); and PDGF receptor a (cat. no. 3164) were all obtained from Cell Signaling. GAPDH was used as a loading control

Be the First to Write a Review!

FGF Receptor 2 (D4H9) Rabbit mAb

FGF Receptor 2 (D4H9) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (31)

Reviews

FGF Receptor 2 (D4H9) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map