Fig 1: Down-regulation of RACK1 in human and mouse pancreatic premalignant lesions. IHC analyses in human PDA and adjacent normal tissues (A, E, n = 32), KPC mice tissues (B, F, n = 3), human ADM, PanINs and PDA (C, G), KPC mouse ADM, PanINs and PDA (D, H). Kaplan–Meier survival curves based on RACK1 protein expression in 32 PDA patients (I). Immunoblot analysis of RACK1 levels in pancreatic cancer cells (J) and in pancreatic cancer cells and pancreatic acinar cells (K). Quantitative analysis of RACK1 levels in pancreatic cancer cells and acinar cells (L)