Anti-CIAS1/NALP3/NLRP3 Antibody Picoband® PA1665 from BosterBio

Product Specs
ItemAnti-CIAS1/NALP3/NLRP3 Antibody Picoband®
CompanyBosterBio
Price $370.00Supplier Page View Company Product Page
Catalog NumberPA1665
Quantity100 µg/vial
ApplicationsIHC,WB,Flow Cytometry
FormatLyophilized, Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4
PurityImmunogen affinity purified
ReactivityHuman,Mouse,Rat
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human CIAS1, different from the related rat and mouse sequences by one amino acid
ClonalityPolyclonal
Gene NameNLRP3
NCBI Gene AliasesMWS, AGTAVPRL, CLR1.1, CIAS1, FCU, FCAS, C1orf7, AVP, KEFH, DFNA34, NALP3, AII, FCAS1, PYPAF1
ConcentrationAdding 0.2 ml of distilled water will yield a concentration of 500 µg/ml
HostRabbit
Molecular Weight118173 MW, Observed: 110 kDa
Calculated: 118173 MW
Research AreaVascular Inflammation
StorageStore at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles
IsotypeIgG
TargetNACHT, LRR and PYD domains-containing protein 3
Antibody TypePrimary Antibodies
Conjugate/TagBiotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, Fluoro647, carrier-free

Questions and Answers

What species does this antibody work with, and has it been used in relevant studies?

The Anti-CIAS1/NALP3/NLRP3 Antibody is reactive with Human, Mouse, and Rat. It has been cited in 82 scientific articles, indicating its utility in various studies involving these species.

Can this antibody be used for flow cytometry, and are there any specific applications documented in the literature?

Yes, this antibody has been tested in Flow Cytometry. It has been utilized in studies related to vascular inflammation, which may provide insights into its application in analyzing immune responses and cell signaling pathways.

What is the sensitivity of this antibody, and how might that impact experimental design?

The sensitivity of the Anti-CIAS1/NALP3/NLRP3 Antibody is between 1 to 10 pg/mL. This high sensitivity allows for the detection of low-abundance proteins, making it suitable for experiments where target protein levels are expected to be minimal.

How should this antibody be stored after reconstitution, and what are the implications for long-term use?

After reconstitution, the antibody should be stored at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Proper storage is crucial to maintain the antibody's integrity and functionality for long-term experiments.

BosterBio

3942 B Valley Ave.

Pleasanton, CA 94566

United States

Phone: (888) 466-3604
Fax: (925)215-2184

Email: support@bosterbio.com

Company Profile

Website: www.bosterbio.com

(1) Combined transcriptomics and network pharmacology to elucidate the mechanisms of rutin in treating ischemic stroke ratPhytomedicine : international journal of phytotherapy and phytopharmacologyNovember 25, 2025Zheng T, Jiang T, Chen Y, Xie J, Yu W, Wang M.

(2) Neuroinflammation in hypothyroidism? Chrysin treatment as a strategy to reduce neuroinflammation induced by hypothyroidismNeuroscienceOctober 1, 2025Bortolotto VC, Zborowski VA, Dahleh MMM, Borstmann SMA, Viana CE, Pinheiro FC, Balok FRM, Meichtry LB, Boeira SP, Guerra GP, et al.

(3) Berberine attenuates the expression of NLRP3 and downstream inflammasome effectors in diabetic retinopathyJournal of natural medicinesSeptember 1, 2025Li N, Chen JL, Sun YJ, Sun JF, Wang TH, Saik AYH, Ong AH.

(4) "Huanglian Jiedu Decoction improves the""central-peripheral""inflammatory microenvironment and enhances the cognitive function of APP/PS1 mice by inhibiting the activation of NLRP3 inflammasome mediated by gut microbiota"Chinese medicineAugust 7, 2025Zhang Y, Wang J, Li X, Guo R, Wang L, Liu Y, Yu Y, Kong L.

(5) NOD3 Reduces Sepsis-Induced Acute Lung Injury by Regulating the Activation of NLRP3 Inflammasome and the Polarization of Alveolar MacrophagesInflammationAugust 1, 2025Zhao Y, Wu Y, Qu L, Hu Y, Sun S, Yao R, Li R.

(6) An Artificial Peroxynitrite-Resistant Superoxide Dismutase for Acute Kidney Injury AlleviationSmall (Weinheim an der Bergstrasse, Germany)August 1, 2025Zhang F, Gao P, Qi M, Hu J, Wu X, Li C, Zhuang Z, Qiu Z, Xu Z.

(7) Melatonin Ameliorates Senescence of Mouse Auditory Cell Line HEI-OC1 Cells by Suppressing NLRP3 Inflammasome-Mediated PyroptosisMolecular neurobiologyAugust 1, 2025Ding Y, Liu Y, Li D, Hu R, Tian Z, Yang L, Li Y, Lin Y, Qu Y.

(8) Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mousmodel of Alzheimer's diseaseAlzheimer's research & therapyApril 5, 2025Chen H, Li N, Liu N, Zhu H, Ma C, Ye Y, Shi X, Luo G, Dong X, Tan T, et al.

(9) Alloferon Mitigates LPS-Induced Endometritis by Attenuating the NLRP3/CASP1/IL-1β/IL-18 Signaling CascadeInflammationApril 1, 2025Chen S, Zhu L, Fang X, Appiah C, Ji Y, Chen Z, Qiao S, Gong C, Li J, Zhao Y.

(10) CPT1A mediated preservation of mitochondrial inhibits pyroptosis in pancreatic acinar cellsFrontiers in cell and developmental biologyJanuary 1, 2025Liu Y, Liu Y, Yu X, Tian S, Li X, Gao Y, Bao X, Wu X, Zhang B, Huang W.

(11) NLRP3 inhibitor combined with Yimusake improves erectile dysfunction in rats with diabetes mellitus through the attenuation of pyroptosisHeliyonOctober 15, 2024Zhu B, Zhang X, Niu L, Yang C, Jin X, Liu F.

(12) Methyltransferase-Like 3-Mediated N6-Methyladenosine RNA Methylation Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cell Pyroptosis by Targeting PTENJournal of the American Heart AssociationOctober 1, 2024Jiang Y, Liu H, Shi R, Hao Y, Zhang J, Xin W, Li Y, Ma C, Zheng X, Zhang L, et al.

(13) CircSSR1 regulates pyroptosis of pulmonary artery smooth muscle cells through parental protein SSR1 mediating endoplasmic reticulum stressRespiratory researchOctober 1, 2024Guan X, Du H, Wang X, Zhu X, Ma C, Zhang L, He S, Bai J, Liu H, Yuan H, et al.

(14) Stress-induced NLRP3 inflammasome activation and myelin alterations in the hippocampus of PTSD ratsNeuroscienceSeptember 13, 2024Yang L, Xing W, Shi Y, Hu M, Li B, Hu Y, Zhang G.

(15) Metformin inhibits activation of NLRP3 inflammasome and inflammatory response in preeclamptic ratsGeneAugust 15, 2024Jia R, Ma H, Hao H, Wang F, Yang H.

(16) Carnosine ameliorates postoperative cognitive dysfunction of aged rats by limiting astrocytes pyroptosisNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeuticsJuly 1, 2024Shen J, Xu J, Wen Y, Tang Z, Li J, Sun J.

(17) Rhizoma Alismatis Decoction improved mitochondrial dysfunction to alleviate SASP by enhancing autophagy flux and apoptosis in hyperlipidemia acute pancreatitisPhytomedicine : international journal of phytotherapy and phytopharmacologyJuly 1, 2024Zhang R, Zhu Z, Ma Y, Tang T, Wu J, Huang F, Xu L, Wang Y, Zhou J.

(18) Apolipoprotein O modulates cholesterol metabolism via NRF2/CYB5R3 independent of LDL receptorCell death & diseaseJune 3, 2024Chen J, Hu J, Guo X, Yang Y, Qin D, Tang X, Huang Z, Wang F, Hu D, Peng D, et al.

(19) PLD2 deletion ameliorates sepsis-induced cardiomyopathy by suppressing cardiomyocyte pyroptosis via the NLRP3/caspase 1/GSDMD pathwayInflammation research : official journal of the European Histamine Research Society ... [et al.]June 1, 2024Li J, Teng D, Jia W, Gong L, Dong H, Wang C, Zhang L, Xu B, Wang W, Zhong L, et al.

(20) In vitro and in silico analyses reveal the toxicity of metolachlor to grass carp hepatocytes and the antagonism of melatoninPesticide biochemistry and physiologyJune 1, 2024Chi Q, Xia Y, Luo D, Zhu L, Yang X, Li S.

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Anti-CIAS1/NALP3/NLRP3 Antibody

Anti-CIAS1/NALP3/NLRP3 Antibody

Anti-CIAS1/NALP3/NLRP3 Antibody

Anti-CIAS1/NALP3/NLRP3 Antibody

Anti-CIAS1/NALP3/NLRP3 Antibody Picoband® from BosterBio

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Anti-CIAS1/NALP3/NLRP3 Antibody Picoband® from BosterBio

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