Anti-Protein CASP antibody [2A10] ab54583 from Abcam

Product Specs
ItemAnti-Protein CASP antibody [2A10]
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab54583
Antibody TypePrimary
Quantity100 UG
HostMouse, Nude mouse
ApplicationsFlow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Sandwich ELISA, Western blot
ClonalityMonoclonal
IsotypeIgG1
Conjugate/TagUnconjugated
Clone2A10
Concentration1 mg/ml
Research AreaEpigenetics
Gene NameCUX1
ReactivityHuman, Recombinant fragment
TargetProtein CASP

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Functional characterization of a single nucleotide polymorphism associated with Alzheimer’s disease in a hiPSC-based neuron modelPLOS ONESeptember 26, 2023Lindsay R. Stolzenburg, Sahar Esmaeeli, Ameya S. Kulkarni, Erin Murphy, Taekyung Kwon, Christina Preiss, Lamiaa Bahnassawy, Joshua D. Stender, Justine D. Manos, Peter Reinhardt, et al.AF568,Abcam ab175477 Tau CP27,Davies Lab [17],1:500,Gt anti-Ms IgG2b AF647,Thermo A-21242 CUX1,Abcam ab54583,1:100,Gt anti-Ms IgG1 AF488,Thermo A-21121 SOX2,Abcam ab97959,1:500,Gt anti-Rb AF568,Abcam ab175471 TUJ1,Biolegend

(2) SARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 KinaseJournal of virologyApril 27, 2023Kettunen P, Lesnikova A, Räsänen N, Ojha R, Palmunen L, Laakso M, Lehtonen Š, Kuusisto J, Pietiläinen O, Saber SH, et al.goat,"1:1,000",Bio-Techne,AF933 Actinin goat,"2, 5, 20 μg/mL",Bio-Techne,AF8279 CTIP2 rat,1:500,Abcam,ab18465 Cux1 mouse,1:500,Abcam,ab54583 GABA rabbit,1:500,Sigma,A2052 GFAP rabbit,1:500,Agilent,Z033429-2 MAP2 chicken,"1:1,000",Abcam,ab92434 Nanog,1:100,ThermoFisher Scientific

(3) Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human modelBrainJune 30, 2022Simoni H Avansini et al.ab5392; 1:1000); rabbit anti-SOX2 (Abcam; ab97959; 1:1000); rabbit anti-CUX1 (CUTL1 or CASP, Abcam; ab54583; 1:200); rabbit anti-vesicular glutamate transporter 1 (VGLUT1; Synaptic Systems; 135311; 1:500); rabbit

(4) Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cellsNature cell biologyJune 1, 2022Rosebrock D, Arora S, Mutukula N, Volkman R, Gralinska E, Balaskas A, Aragonés Hernández A, Buschow R, Brändl B, Müller FJ, et al.SOX2 (ab79351; 1:500), SATB2 (ab51502; 1:50), CTIP2 (ab18465; 1:250), TBR1 (ab31940; 1:500) and CUX1 (ab54583; 1:200) were from Abcam. The antibodies to OCT3/4 (sc5279; 1:22) and LIFR (sc-515337; 1:100) were from

(5) Identification of SOX2 Interacting Proteins in the Developing Mouse Lung With Potential Implications for Congenital Diaphragmatic HerniaFrontiers in PediatricsMay 9, 2022Kim A. A. Schilders et al.against CHD4 (Abcam; ab72418), FOXP2 (Abcam; ab16046), FOXP4 (Santa Cruz; sc-292474), or CUX1 (Abcam, Ab54583) diluted in blocking buffer at 4°C overnight. After washing in PBS with 0.05% Tween20, slides were incubated

(6) Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron contentNature communicationsMay 2, 2022Papes F, Camargo AP, de Souza JS, Carvalho VMA, Szeto RA, LaMontagne E, Teixeira JR, Avansini SH, Sánchez-Sánchez SM, Nakahara TS, et al.2748; 1:500); rabbit anti-GAD65/67 (Abcam; ab11070; 1:200); rabbit anti-CUX1 (CUTL1 or CASP) (Abcam; ab54583; 1:200); rabbit anti-TCF4 (Abcam; ab217668; 1:1000); rabbit anti-vGLUT1 (Synaptic Systems; 135311; 1:500);

(7) CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent ProliferationCancersMay 18, 2021Griesmann H, Mühl S, Riedel J, Theuerkorn K, Sipos B, Esposito I, Vanden Heuvel GB, Michl P.0.05% BSA for 1 h at room temperature, followed by incubation with the primary antibody against CUX1 (ab54583, Abcam; 1:200), diluted in antibody diluent (Dako, Burlington, ON, Canada) overnight at 4 °C. After

(8) Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-NeuronsThe Journal of NeuroscienceMay 12, 2021Derek H. Oakley, Naomi Klickstein, Caitlin Commins, Mirra Chung, Simon Dujardin, Rachel E. Bennett, Bradley T. Hyman, Matthew P. Froschmarkers was performed using antibodies against Tuj1 (1:500; TUJ, Aves), CUX1/CUTL1 (1:300; catalog #ab54583, Abcam), Brn2 (1:300; catalog #ab1377469, Abcam), Ctip2 (1:100; catalog #ab18465, Abcam), and Tbr1 (1:1000;

(9) Hyperactive Behavior and Altered Brain Morphology in Adult Complement C3a Receptor Deficient MiceFrontiers in ImmunologyFebruary 22, 2021Andrea Pozo-Rodrigálvarez, Roosa Ollaranta, Jenny Skoog, Milos Pekny, Marcela Peknaprimary antibody [anti-NeuN biotinylated (1:200, MAB 377B, Millipore, MA, USA), anti-Cux-1 (1:1,000, ab54583, Abcam), anti-Tbr-1 (1:1,000, ab31940, Abcam)], in blocking buffer. One section per slide was incubated

(10) Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickasesCommunications biologyFebruary 12, 2021Ye T, Duan Y, Tsang HWS, Xu H, Chen Y, Cao H, Chen Y, Fu AKY, Ip NY.(1:1,000, #414000, Life Technologies), anti-TRA-1-81 (1:1,000, #MAB4381, Millipore), anti-Cux1 (1:500, #ab54583, Abcam), anti-APP (6E10; 1:2,000, #803016, Biolegend), anti-human phospho-Tau at Thr231 (AT180; 1:1,000,

(11) A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell modelsPloS oneJanuary 1, 2021Ortolano NA, Romero-Morales AI, Rasmussen ML, Bodnya C, Kline LA, Joshi P, Connelly JP, Rose KL, Pruett-Miller SM, Gama V.SOX3 (Thermo Fisher, Cat. PA5-35983), TM7SF2 (Thermo Scientific, Cat. 12033-1-AP), CUX1 (Abcam, Cat. ab54583), and SCD1 (Bethyl, Laboratories, Cat. A305-259A-T). See full list of antibody information in S7 Table. HRP-conjugated

(12) mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortexeLifeSeptember 2, 2020Andrews MG, Subramanian L, Kriegstein AR.sc-398703, 1:250), Cofilin (Santa Cruz, sc-376476, 1:100), Cdc42 (Santa Cruz, sc-8401, 1:200) Cux1 (Abcam, AB54583, 1:500), pVim (Fisher, 5045934, 1:500), pHistone H3 (abcam, ab14955, 1:500), Cryab (ab13496, 1:500),

(13) Transient microglial absence assists postmigratory cortical neurons in proper differentiationNature communicationsApril 2, 2020Hattori Y, Naito Y, Tsugawa Y, Nonaka S, Wake H, Nagasawa T, Kawaguchi A, Miyata T.Santa Cruz Biotechnology); rat anti-Ctip2 mAb (1:1000, Cat#ab18465, Abcam); mouse anti-Cux1 mAb (1 µg ml−1, Cat#ab54583, Abcam); rabbit anti-RORβ pAb (1 µg ml−1, Cat#LS-A2374, LifeSpan BioSciences, Seattle, WA, USA); mouse

(14) Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional outputNature neuroscienceApril 1, 2019Giandomenico SL, Mierau SB, Gibbons GM, Wenger LMD, Masullo L, Sit T, Sutcliffe M, Boulanger J, Tripodi M, Derivery E, et al.anti-RYK (Abcam, ab5518), rabbit anti-Netrin 1 [EPR5428] (Abcam, ab126729), mouse anti-CUX1 [2A10] (Abcam, ab54583), rabbit anti-GFAP (Abcam, ab7260), rabbit anti-SOX5 (Abcam, ab94396). All primary antibodies are well-described

(15) METTL3-mediated N⁶-methyladenosine mRNA modification enhances long-term memory consolidationCell researchNovember 1, 2018Zhang Z, Wang M, Xie D, Huang Z, Zhang L, Yang Y, Ma D, Li W, Zhou Q, Yang YG, et al.labeling were as follows: anti-METTL3 (1:200 dilution, Abcam, ab195352), anti-CUX1 (10 μg/ml, Abcam, ab54583), anti-EGR1 (1:500 dilution, Invitrogen, MA515008), goat-anti-rabbit Alexa Fluor 594 (1:500, Abcam,

(16) Cell diversity and network dynamics in photosensitive human brain organoidsNatureMay 4, 2017Quadrato G, Nguyen T, Macosko EZ, Sherwood JL, Min Yang S, Berger DR, Maria N, Scholvin J, Goldman M, Kinney JP, et al.Antibody,Host,Company,Catalog,Dilution AP2α,Mouse,U of Iowa,3B5,1:100 CTIP2,Rat,Abcam,AB18465,1:100 CUX1,Mouse,Abcam,AB54583,1:350 DCX,Goat,Santa Cruz,SC8066,1:300 EMX1,Rabbit,Sigma,HPA006421,1:50 FOXG1,Rabbit,Abcam,AB18259,1:300 GFAP,Mouse,Sigma,G3893,1:400 GABA,Rabbit,Sigma,A2052,1:1000 GS,Rabbit,Abcam,AB73593,1:200 HIF1α,Mouse,Abcam,AB16066,1:200 ISL1,Rabbit,Abcam,AB109517,1:2000 MAP2,Chicken,Abcam,AB5392,1:5000 MITF,Mouse,Exalpha,X2398M,1:500 Nestin,Mouse,Abcam,AB6142,1:100 NKX2.1,Rabbit,DSBS,74.5A5,1:250 OTX2,Rabbit,Abcam,AB21990,1:100 PAX6,Rabbit,Biolegend,901301,1:400 SYN1,Mouse,SYSY,106

(17) Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitorsNature communicationsMarch 23, 2015Edri R, Yaffe Y, Ziller MJ, Mutukula N, Volkman R, David E, Jacob-Hirsch J, Malcov H, Levy C, Rechavi G, et al.

(18) CUX1 modulates polarization of tumor-associated macrophages by antagonizing NF-κB signalingOncogeneJanuary 8, 2015Kühnemuth B, Mühlberg L, Schipper M, Griesmann H, Neesse A, Milosevic N, Wissniowski T, Buchholz M, Gress TM, Michl P.

(19) BDNF-Dependent Plasticity Induced by Peripheral Inflammation in the Primary Sensory and the Cingulate Cortex Triggers Cold Allodynia and Reveals a Major Role for Endogenous BDNF As a Tuner of the Affective Aspect of PainJournal of NeuroscienceOctober 29, 2014Karine Thibault, Wee Khang Lin, Armelle Rancillac, Marie Fan, Thibaut Snollaerts, Vallier Sordoillet, Michel Hamon, George M Smith, Zsolt Lenkei, Sophie Pezetanti-Iba1, no. 019-19741, Wako Chemicals) or 1:1000 Cutl1, a pyramidal marker (mouse anti-Cutl1, no. ab54583, Abcam). Following several washes, sections were incubated in AlexaFluor 568 anti-rabbit IgG or AlexaFluor

(20) The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neuronsHuman molecular geneticsJuly 1, 2014Christina R Muratore, Heather C Rice, Priya Srikanth, Dana G Callahan, Taehwan Shin, Lawrence N P Benjamin, Dominic M Walsh, Dennis J Selkoe, Tracy L Young-Pearse

Write a Review

(1)

10/1/2020Immunostaining for Layer II/III marker in Brain Neocortex Bhavin ShahCUTL1/CUX1 antibody was used to specifically label layer II/III neurons in the postnatal brain neocortex.

Anti-Protein CASP antibody [2A10] from Abcam

Abcam

Citations (25)

Reviews

Anti-Protein CASP antibody [2A10] from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map