RAT ANTI MOUSE ER-MP58

Published Investigator image:
Rat anti Mouse ER-MP58 antibody, clone ER-MP58 (MCA2391) used to demonstrate recruited macrophages in atherosclerotic lesions by immunohistochemistry on acetone fixed sections.
Image caption:
Increased leukocyte adhesion and newly recruited myeloid cells in IκBα^del mice. (A) In IκBα^del mice, more leukocytes adhere to the endothelial cell layer delineating the lesion (*** p<0.0001; n = 17/17). Representative pictures from (B) IκBα^WT and (C) IκBα^del lesions, original magnification ×200. (D) Lesions from IκBα^del mice contain more ER-MP58 positive cells, suggesting an increased attraction myeloid cells (** p<0.001; n = 19/17). Representative pictures from (E) IκBα^WT and (F) IκBα^del lesions, original magnification ×200.

From: Goossens P, Vergouwe MN, Gijbels MJJ, Curfs DMJ, van Woezik JHG, Hoeksema MA, et al. (2011)
Myeloid IκBα Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques.
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Published Investigator image:
Rat anti Mouse ER-MP58 antibody, clone ER-MP58 (MCA2391) used to demonstrate recruited macrophages in atherosclerotic lesions by immunohistochemistry on acetone fixed sections.
Image caption:
Increased leukocyte adhesion and newly recruited myeloid cells in IκBα^del mice. (A) In IκBα^del mice, more leukocytes adhere to the endothelial cell layer delineating the lesion (*** p<0.0001; n = 17/17). Representative pictures from (B) IκBα^WT and (C) IκBα^del lesions, original magnification ×200. (D) Lesions from IκBα^del mice contain more ER-MP58 positive cells, suggesting an increased attraction myeloid cells (** p<0.001; n = 19/17). Representative pictures from (E) IκBα^WT and (F) IκBα^del lesions, original magnification ×200.

From: Goossens P, Vergouwe MN, Gijbels MJJ, Curfs DMJ, van Woezik JHG, Hoeksema MA, et al. (2011)
Myeloid IκBα Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques.
PLoS ONE 6(7): e22327.

Published Investigator image:
Rat anti Mouse ER-MP58 antibody, clone ER-MP58 (MCA2391) used to demonstrate recruited macrophages in atherosclerotic lesions by immunohistochemistry on acetone fixed sections.
Image caption:
Increased leukocyte adhesion and newly recruited myeloid cells in IκBα^del mice. (A) In IκBα^del mice, more leukocytes adhere to the endothelial cell layer delineating the lesion (*** p<0.0001; n = 17/17). Representative pictures from (B) IκBα^WT and (C) IκBα^del lesions, original magnification ×200. (D) Lesions from IκBα^del mice contain more ER-MP58 positive cells, suggesting an increased attraction myeloid cells (** p<0.001; n = 19/17). Representative pictures from (E) IκBα^WT and (F) IκBα^del lesions, original magnification ×200.

From: Goossens P, Vergouwe MN, Gijbels MJJ, Curfs DMJ, van Woezik JHG, Hoeksema MA, et al. (2011)
Myeloid IκBα Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques.
PLoS ONE 6(7): e22327.