Shh (C9C5) Rabbit mAb 2207S from Cell Signaling Technology

Product Specs
ItemShh (C9C5) Rabbit mAb
CompanyCell Signaling Technology
Price $336.00 Inquire
Catalog Number2207S
Quantity100 µl
ApplicationsW
ReactivityH, R
TargetSHH
HostRabbit
NCBI Gene AliasesHHG1, HLP3, HPE3, MCOPCB5, SMMCI, ShhNC, TPT, TPTPS
ClonalityMonoclonal
NCBI Full Gene Namesonic hedgehog signaling molecule
Research AreaDevelopmental Biology
IsotypeIgG
CloneC9C5
Molecular Weight19, (45 kDa precursor)

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Circ_0081343 promotes autophagy and alleviates pyroptosis via PI3 K/AKT/HIF-1α axis in hypoxia-induced fetal growth restriction of miceAnim Cells Syst (Seoul)May 12, 2025Linmei Zheng, Rong Tang, Fiaz Ahmad, Junbo Fang, Lei Shi, Xiaoju Chen, Jing Li1:1000, ab128874, Abcam), anti-P62 (dilution 1:1000, ab38898, Abcam), anti-PI3 K (dilution 1:1000, 2207s, CST, USA), and anti-AKT (dilution 1:1000, 2643s, CST, USA) antibodies. Subsequently, the membranes

(2) Molecular characteristics and cancer immunity of LRP1B and its relationship with the Hedgehog signaling pathway in colorectal cancerFrontiers in ImmunologyMarch 18, 2025Yuan Liu, Yang Zhong, Yaodong Sang, Siqiang Zhu, Kang Xu, Xingyu Zhu, Xiaoling Cui, Xinyu Liu, Xiaohan Wang, Hao Chen, et al.the Amersham ImageQuant 800 system. The following primary antibodies were purchased: SHH (1:1,000, 2207T, Cell Signaling Technology, Shengxia Road, Pudong New Area, Shanghai, China), PTCH1 (1:1,000, 2468T,

(3) COLEC10: A potential tumor suppressor and prognostic biomarker in hepatocellular carcinoma through modulation of EMT and PI3K-AKT pathwaysOpen Life SciFebruary 26, 2025Rui-Sheng Ke, Yun Dai, Yan-ling Tu, Zhao-Hui Liu, Kun-Zhai Huang, Fu-Xing Zhangthis study were N-cadherin (#13116T), E-cadherin (#14472S), Vimentin (#5741T), GLI1 (#3538T), SHH (#2207T), PTCH1 (#2468T), SMO (#92981S), phospho-AKT (#2920S), PI3K (#4257), AKT (#4060T), and phospho-PI3K

(4) Sonic Hedgehog Is an Early Oligodendrocyte Marker During RemyelinationCellsNovember 1, 2024Russo M, Zahaf A, Kassoussi A, Sharif A, Faure H, Traiffort E, Ruat M.wells) and 6 µg of rat brain lysates were run. Rabbit monoclonal antibody against SHHN (C9C5 1/1000, #2207, Cell Signaling, Danvers, MA, USA) and mouse antibodies against Actin (1/2000, #A4700), MBP (1/500,

(5) Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shiftsiScienceJuly 19, 2024Zhang Q, Ding L, Yan Y, Zhai Q, Guo Z, Li Y, Tang Z, Zang P, Ni C, Zhang S, et al.AB_2622225 Anti-PDPK1/PDK1,GeneTex,Cat# GTX50366; RRID: AB_11179547 Anti-Shh (C9C5) Rabbit mAb,Cell Signaling Technology,Cat# 2207; RRID: AB_2188191 Anti-EREG (D4O5I) Rabbit mAb,Cell Signaling Technology,Cat# 12048; RRID: AB_2797808 Anti-PLGF,GeneTex,Cat#

(6) Polysaccharides from Basella alba Protect Post-Mitotic Neurons against Cell Cycle Re-Entry and Apoptosis Induced by the Amyloid-Beta Peptide by Blocking Sonic Hedgehog ExpressionInternational Journal of Molecular SciencesJuly 3, 2024Bo-Yu Hou, Ming-Hsuan Wu, Hui-Yu Hsu, Yi-Chun Lin, Ding-I YangAbcam), cleaved caspase-3 (1:1000; Cat. No. 9664, Cell Signaling Technology), and SHH (1:500; Cat. No. 2207, Cell Signaling Technology) were diluted in signal enhancer HIKARI solution 1 (Cat. No. NT08044-71R,

(7) Cytoneme signaling provides essential contributions to mammalian tissue patterningCellJanuary 18, 2024Hall ET, Dillard ME, Cleverdon ER, Zhang Y, Daly CA, Ansari SS, Wakefield R, Stewart DP, Pruett-Miller SM, Lavado A, et al.,Thermo Fisher Scientific,Cat# MA3-061; RRID:AB_2056321 Rabbit monoclonal anti-SHH (C9C5),Cell Signaling Technology,Cat# 2207; RRID:AB_2188191 Rabbit monoclonal anti-KIF5B,Abcam,Cat# ab167429; RRID:AB_2715530 Mouse monoclonal

(8) CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinomaCancer cell internationalDecember 12, 2023Jian Y, Zhang L, Gong L, Ding M, Sun X, Yu X, Lv S, Li J, Yang D, Wang S.#2520), PTCH2 (1:1000, Cell Signaling Technology, #2470), SHH (1:1000, Cell Signaling Technology, #2207), GLi1 (1:400, Cell Signaling Technology, #3538), SMO (1:1000, Cell Signaling Technology, #92981), β-catenin

(9) The long noncoding RNA TINCR promotes self-renewal of human liver cancer stem cells through autophagy activationCell Death DisNovember 16, 2022Jing Shi, Cao Guo, Yang Li, Junli MaNotch1 (1:1000 dilution, #3608S, CST), β-Catenin (1:1000 dilution, #8480 S, CST), SHH (1:1000 dilution, #2207S, CST), β-Actin (1:1000 dilution, #8457S, CST), and GAPDH (1:2000 dilution, 10494-1-AP, Proteintech),

(10) Elevated NF-κB/SHh/GLI1 Signature Denotes a Worse Prognosis and Represent a Novel Potential Therapeutic Target in Advanced Prostate CancerCellsJuly 5, 2022Davide Vecchiotti, Daniela Verzella, Mauro Di Vito Nolfi, Daniel D’Andrea, Irene Flati, Barbara Di Francesco, Jessica Cornice, Edoardo Alesse, Daria Capece, Francesca Zazzeroni(1:1000, sc-372) and Shh (1:500, sc-9024) were purchased from Santa Cruz Biotechnology; Shh (1:1000, #2207), GLI1 (1:1000, #2643), IκBα (1:1000, #9242), and GAPDH (1:1000, #5174) were purchased from Cell Signaling technologies

(11) Collagen type IV alpha 1 (COL4A1) silence hampers the invasion, migration and epithelial–mesenchymal transition (EMT) of gastric cancer cells through blocking Hedgehog signaling pathwayBioengineeredApril 1, 2022Xijuan Cui, Tao Shan, Lina Qiao1:2000; Abcam), E-cadherin (#3195; 1:1000; Cell signaling pathway), Gli1 (ab134906; 1:500; Abcam), Shh (#2207; 1:1000; Cell signaling pathway) and GAPDH (ab9485; 1:2500; Abcam) at 4°C overnight. The secondary antibodies

(12) Sonic Hedgehog Induces Mesenchymal Stromal Cell Senescence-Associated Secretory Phenotype and Chondrocyte Apoptosis in Human Osteoarthritic CartilageFrontiers in Cell and Developmental BiologySeptember 27, 2021Meng Feng, Wenguang Liu, Jing Ding, Yusheng Qiu, Qian Chenprotein samples were loaded and transferred to nitrocellulose membrane probed with anti-SHH antibody (Cat#2207, at 1:1,000 dilution, Cell Signaling Technology, Danvers, MA, United States), anti-SMO antibody (Cat#ab235183,

(13) Circular RNA circBCBM1 promotes breast cancer brain metastasis by modulating miR-125a/BRD4 axisInternational Journal of Biological SciencesJuly 22, 2021Bo Fu et al.with primary antibodies, including anti-BRD4 (ab128874, Abcam), anti-MMP9 (ab38898, Abcam), anti-Shh (2207s, CST), anti-Gli1 (2643s, CST) and anti-GAPDH (sc-32233, Santa Cruz Biotechnology). Membranes were then

(14) Cell-Intrinsic Tumorigenic Functions of PPARγ in Bladder Urothelial CarcinomaMolecular cancer research : MCRApril 1, 2021Sanchez DJ, Missiaen R, Skuli N, Steger DJ, Simon MC.1:10,000), and secondary antibodies were diluted 1:2000 in 5% w/v nonfat milk. PPARγ (cat. 2435), Shh (cat. 2207), MMP3 (Cat. 14351), MMP9 (Cat. 13667), TIMP1 (Cat. 8946), KRT5 (Cat. 25807), FOXA1 (Cat. 53528), GAPDH

(15) Exovesicular-Shh confers Imatinib resistance by upregulating Bcl2 expression in chronic myeloid leukemia with variant chromosomesCell death & diseaseMarch 11, 2021Anusha, Dalal H, Subramanian S, V P S, Gowda DA, H K, Damodar S, Vyas N.No.,Antibody (western),Catalog number,Company,Use 1.,Shh-rabbit,2207,Cell Signaling Technologies (CST),Western blot (WB) and immunohistochemistry (IHC) 2.,Gli1-rabbit,SAB2700185,Sigma,WB 3.,Bcl2-mouse,ab692,abcam,WB 4.,GM130-rabbit,ab187514,abcam,WB 5.,Actin-rabbit,ab8227,abcam,WB 6.,Gapdh-rabbit,2118,CST,WB 7.,Flotillin-2-rabbit,F1805,Sigma,WB 8.,Tsg101-rabbit,ab83,abcam,WB 9.,Smoothened-rabbit,ab236465,abcam,WB 10.,MCl-1-rabbit,4572,CST,WB 11.,BCl-xL-rabbit,2762,CST,WB 12.,Patched-rabbit,Ab53715,Abcam,"WB,

(16) Targeting the Sonic Hedgehog Pathway to Suppress the Expression of the Cancer Stem Cell (CSC)-Related Transcription Factors and CSC-Driven Thyroid Tumor GrowthCancersJanuary 22, 2021Lu Y, Zhu Y, Deng S, Chen Y, Li W, Sun J, Xu X.ethanol. For in vivo experiments, GANT61 was diluted in corn oil. Antibodies against Shh (Catalog # 2207), Gli1 (Catalog # 2643), Snail (Catalog # 3895), Bmi1 (Catalog # 6964) were purchased from Cell Signaling Technology

(17) RUNX1 regulates the proliferation and chemoresistance of colorectal cancer through the Hedgehog signaling pathwayJournal of CancerJanuary 1, 2021Li Q, Lai Q, He C, Zhang H, Pan X, Li H, Yan Q, Fang Y, Liu S, Li A.the following: RUNX1 (#4336, CST), PTCH1 (#2468, CST), PTCH2 (#2470, CST), GLI1 (#3538, CST), Shh (#2207, CST), ABCG2 (#42078, CST) and GAPDH (60004-1-Ig, Proteintech). IHC was performed following the manufacturer's

(18) Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling PathwayDevelopmental cellNovember 9, 2020Petrov K, Wierbowski BM, Liu J, Salic A.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies rabbit monoclonal anti-SHH (clone C9C5),Cell Signaling Technology,Cat# 2207S; RRID: AB_2188191 rabbit monoclonal anti-WNT3A (clone C64F2),Cell Signaling Technology,Cat# 2721; RRID:

(19) Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog LigandDevelopmental CellNovember 1, 2020Bradley M. Wierbowski, Kostadin Petrov, Laura Aravena, Garrick Gu, Yangqing Xu, Adrian Salic1984",Cat# T6199; RRID: AB_477583 rabbit monoclonal anti-SHH (clone C9C5),Cell Signaling Technology,Cat# 2207S; RRID: AB_2188191 mouse monoclonal anti-SHH (clone 5E1),"DSHB; Ericson et al., 1996",Cat# 5e1; RRID:

(20) LINC00294 induced by GRP78 promotes cervical cancer development by promoting cell cycle transitionOncology LettersSeptember 21, 2020Jiangnan Qiu, Shulin Zhou, Wenjun Cheng, Chengyan Luono. 4129), CDK4 (1:1,000; cat. no. 12790), Gli1 (1:1,000; cat. no. 3538T), Sonic (1:1,000; cat. no. 2207T) and GAPDH (1:1,000; cat. no. 5174T; Cell Signaling Technology, Inc.) overnight at 4˚C. Subsequently,

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Shh (C9C5) Rabbit mAb

Shh (C9C5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Shh (C9C5) Rabbit mAb from Cell Signaling Technology

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