Numb (C29G11) Rabbit mAb 2756S from Cell Signaling Technology

Product Specs
ItemNumb (C29G11) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2756S
Quantity100 µl
ApplicationsW, IP, IF-F, IF-IC
ReactivityH, M, R, Mk
TargetNumb
HostRabbit
NCBI Gene AliasesC14orf41, S171, c14_5527
ClonalityMonoclonal
NCBI Full Gene NameNUMB endocytic adaptor protein
Research AreaDevelopmental Biology
IsotypeIgG
CloneC29G11
Molecular Weight72, 74

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) EMT-induced stem cell and mesenchymal programs can be decoupled via cell division and ESRP1-dependent mechanismsiScienceDecember 1, 2025Petra den Hollander, Maria Castaneda, Suhas V. Vasaikar, Joanna Joyce Maddela, Claire Gould, Breanna R. Demestichas, Robiya Joseph, Shivangi Agarwal, Abhijeet P. Deshmukh, Alvina Zia, et al.AB_397580 FOXC2,Bethyl,A302-383A; RRID: AB_1907266 ESRP1,Novus,NBP2-57822 NICD,Abcam,ab8925; RRID: AB_306863 NUMB,Cell Signaling,2756; RRID: AB_2154298 ,, "Chemicals, peptides, and recombinant proteins","Chemicals, peptides, and recombinant

(2) A Four Amino Acid Intracellular Motif of VISTA Blocks Growth Receptor Signaling in Cancer Cells to Induce Tumor SuppressionCancer ResearchSeptember 15, 2025Yan Zhao, Tina Andoh, Fatima Charles, Priyanka Reddy, Kristina Paul, Harsh Goar, Ishrat Durdana, Caiden J. Golder, Ashley N. Hardy, Marisa M. Juntilla, et al.AB_2687655), α-actin (Invitrogen, #MA515452, RRID: AB_11001306), α-NUMB (Cell Signaling Technology, #2756S, RRID: AB_2154298), α-Rab11FIP1 (Cell Signaling Technology, #12849S, RRID: AB_2798044), α-Rab11 (Cell Signaling Technology

(3) Dysregulation of FGFR1 signaling in the hippocampus facilitates depressive disorderExperimental & Molecular MedicineAugust 15, 2025Jongpil Shin, Hyeonsik Oh, Ji Hye Park, Hyunsik Bae, Chan Mo Yang, Minju Lee, Seokhwi Kim, Won Do Heo(Cell Signaling Technology, cat. no. 46879) 1:1,000, rabbit anti-Numb (Cell Signaling Technology, cat. no. 2756) 1:1,000, Rabbit anti-BDNF (EPR1292) (Abcam, cat. no. ab108319) 1:1,000, mouse anti-GAPDH (GA1R) (ThermoFisher,

(4) A central role for Numb/Nbl in multiple Shh-mediated axon repulsion processesiScienceMay 16, 2025Tiphaine Dolique, Sarah Baudet, Frederic Charron, Julien Ferentwere immunostained with anti-Numb/NumbLike antibody (Abcam, ab14140 or Cell Signaling Technology, #2756), anti-Tag-1 (R&D Systems, AF4439) and anti-L1 (Chemicon MAB5272). Retinal explants were permeabilized

(5) Mechanical control of the alternative splicing factor PTBP1 regulates extracellular matrix stiffness induced proliferation and cell spreadingiScienceApril 18, 2025Pei-Li Tseng, Weiwei Sun, Ahmed Salem, Mubarak Alaklobie, Sarah C. Macfarlane, Annica K.B. Gad, Mark O. Collins, Kai S. ErdmannSanta Cruz, sc-374152), Nucleolin (1:300; Santa Cruz, sc-8031), Numb (1:1000; Cell Signaling Technology, 2756), Integrin β-1 (1:1000; Santa Cruz, sc-374429), Transferrin receptor 1 (TfR1) (1:1000; Cell Signaling Technology

(6) VISTA-induced tumor suppression by a four amino acid intracellular motifbioRxivJanuary 5, 2025Yan Zhao, Tina Andoh, Fatima Charles, Priyanka Reddy, Kristina Paul, Harsh Goar, Ishrat Durdana, Caiden Golder, Ashley Hardy, Marisa M. Juntilla, et al.(Cell Signaling #4695), α-PD-L1 (Cell Signaling #13684), α-actin (Invitrogen #MA515452), α-NUMB (Cell Signaling # 2756S), α-Rab11FIP1 (Cell Signaling #12849S), α-Rab11 (Cell Signaling #5589S), α-Rab7 (Cell Signaling #9367),

(7) Loss of NUMB drives aggressive bladder cancer via a RHOA/ROCK/YAP signaling axisNature CommunicationsDecember 3, 2024F. A. Tucci, R. Pennisi, D. C. Rigiracciolo, M. G. Filippone, R. Bonfanti, F. Romeo, S. Freddi, E. Guerrera, C. Soriani, S. Rodighiero, et al.1:1000 for IB) (#MABN2311 from Merck Life Science Srl); anti-NUMB rabbit monoclonal (clone C29G11) (#2756 from Cell Signaling Technologies, 1:500 for IF, 1:150 for IHC); anti-phospho MST1 (Thr183)/MST2(Thr180)

(8) NUMB dysfunction defines a novel mechanism underlying hyperuricemia and goutCell discoveryOctober 22, 2024Chi J, Chen Y, Li C, Liu S, Che K, Kong Z, Guo Z, Chu Y, Huang Y, Yang L, et al.with 5% skimmed milk for 1 h and probed overnight at 4 °C with a rabbit anti-NUMB antibody (Cat. No. 2756, Cell Signaling; 1:1000), a mouse anti-NUMB antibody (Cat. No. sc-136554, Santa cruz; 1:200), a mouse

(9) Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile functioneLifeMay 2, 2024Rita De Gasperi, Laszlo Csernoch, Beatrix Dienes, Monika Gonczi, Jayanta K Chakrabarty, Shahar Goeta, Abdurrahman Aslan, Carlos A Toro, David Karasik, Lewis M Brown, et al.milk (blocking solution), and incubated overnight at 4°C with a rabbit monoclonal anti-Numb antibody (#2756, Cell Signaling Technology, Inc, Danvers, MA; RRID:AB_2154298) at 1:1000 dilution in 5% BSA in TBS-T.

(10) Role of PLK1/NUMB/NOTCH in epithelial-mesenchymal transition in human melanomanpj Precision OncologyJanuary 6, 2024Gagan Chhabra, Chandra K. Singh, Mary A. Ndiaye, Shengqin Su, Carl A. Shirley, Nihal Ahmadand quantified using BCA Assay (ThermoFisher). Primary antibodies against PLK1 (#4513, 1:20), NUMB (#2756, 1:40), NOTCH1 (NICD) (#3608, 1:50), E-cadherin (#3195, 1:20), N-cadherin (#13116, 1:50X), Vimentin

(11) SEPTIN 7 INTERACTS WITH NUMB TO PRESERVE SARCOMERE STRUCTURAL ORGANIZATION AND MUSCLE CONTRACTILE FUNCTIONbioRxiv : the preprint server for biologyOctober 16, 2023De Gasperi R, Csernoch L, Dienes B, Gonczi M, Chakrabarty JK, Goeta S, Aslan A, Toro CA, Karasik D, Brown LM, et al.milk (blocking solution) and incubated overnight at 4°C with a rabbit monoclonal anti-Numb antibody (#2756, Cell Signaling Technology, Inc., Danvers, MA) at 1:1000 dilution in 5% BSA in TBS-T. Membranes were

(12) Giant worm-shaped ESCRT scaffolds surround actin-independent integrin clustersThe Journal of cell biologyJuly 3, 2023Stempels FC, Jiang M, Warner HM, Moser ML, Janssens MH, Maassen S, Nelen IH, de Boer R, Jiemy WF, Knight D, et al.A/C,Rabbit,1:200,Abcam,ab108595, LAMP1,Mouse,1:200,BioLegend,328601, LC3,Rabbit,1:100,CST,2775S, NUMB,Rabbit,1:100,CST,2756S, PDI,Rabbit,1:100,Novus Bio,NB300-517, S100a8,Mouse,1:200,Proteintech,66853-1-Ig, S100a9,Rabbit,1:200,Thermo Fisher Scientific

(13) Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancereLifeNovember 8, 2022Xu T, Verhagen M, Joosten R, Sun W, Sacchetti A, Munoz Sagredo L, Orian-Rousseau V, Fodde R.ab78960, RRID:AB_1603730",WB (1.1000) Antibody,Anti-human NUMB (rabbit monoclonal),Cell Signaling,"Cat# 2756, RRID:AB_2534177",WB (1.1000) Antibody,Anti-human B-actin (rabbit monoclonal),Cell Signaling,"Cat#

(14) Notch, Numb and Numb-like responses to exercise-induced muscle damage in human skeletal muscleExperimental physiologyAugust 1, 2022Bubak MP, Stout K, Tomtschik J, Peterson E, Cardozo CP, Graham ZA, Gallagher P.washed in TBS-T, then placed in a solution of 1% milk/TBS-T with primary antibody. Numb (catalog number 2756, Cell Signaling Technology, Inc., Danvers, MA), Numbl (catalog number sc-390590, Santa Cruz Biotechnology, Inc

(15) Endocytic trafficking of GAS6-AXL complexes is associated with sustained AKT activationCellular and molecular life sciences : CMLSMay 27, 2022Poświata A, Kozik K, Miączyńska M, Zdżalik-Bielecka D.anti-TYRO3 (5585, WB 1:1000), rabbit anti-phospho-AXL (Tyr702) (5724, WB 1:1000), rabbit anti-NUMB (2756, WB 1:1000) all from Cell Signaling Technology; mouse anti-α-tubulin (T5168, WB 1:10,000), mouse anti-β-actin

(16) Exclusion of NUMB Exon12 Controls Cancer Cell Migration through Regulation of Notch1-SMAD3 CrosstalkInternational journal of molecular sciencesApril 14, 2022Zhan Z, Yuan N, You X, Meng K, Sha R, Wang Z, Peng Q, Xie Z, Chen R, Feng Y.All cell lines were incubated at 37 °C in a humidified 5% CO2 atmosphere. Antibodies including NUMB (2756S), N-cadherin (13116S), E-cadherin (3195S), Vimentin (5741S), Fibronectin (26836S), pan-keratin (4545T),

(17) Numb and Numblike regulate sarcomere assembly and maintenanceThe Journal of clinical investigationFebruary 1, 2022Wang B, Yang M, Li S.in between. The following antibodies were used for immunostaining: rabbit-anti-Numb (Cell Signaling, 2756s, 1:200 dilution), mouse anti-α-Actinin (Sigma, A7811, 1:500 dilution), mouse anti-α-Actin (Sigma, A9357,

(18) MAD2B promotes podocyte injury through regulating Numb-dependent Notch 1 pathway in diabetic nephropathyInternational journal of biological sciencesJanuary 1, 2022Li MR, Lei CT, Tang H, Yin XJ, Hao Z, Qiu Y, Xie YR, Zeng JY, Su H, Zhang C.incubated with the primary antibody for MAD2B (1:100, ab180579, Abcam, Cambridge, MA, USA), Numb (1:200, #2756, Cell Signaling Technology, Danvers, MA, USA) and WT1 (1:100, ab88901, Abcam, Cambridge, MA, USA) overnight

(19) Numb Promotes Autophagy through p53 Pathway in Acute Kidney Injury Induced by CisplatinAnalytical cellular pathology (Amsterdam)January 1, 2022Liu Z, Li Y, He Y, Wang J.our previous study [8]. The primary antibodies used in the present study were as follows: Numb (cat: 2756, CST, Beverly, MA) (1 : 1000), p53 (cat: sc-126, Santa, USA) (1 : 1000), LC3 (cat: 4108, CST, Beverly,

(20) Optimal empiric treatment for KPC-2-producing Klebsiella pneumoniae infections in critically ill patients with normal or decreased renal function using Monte Carlo simulationBMC Infectious DiseasesDecember 1, 2021Guoan Wang, Wei Yu, Yushan Cui, Qingyi Shi, Chen Huang, Yonghong Xiaodiverse Escherichia coli and Klebsiella pneumoniae isolates. Antimicrob Agents Chemother. 2009;53(7):2756–61. https://doi.org/10.1128/AAC.01678-08. Publisher’s Note Springer Nature remains neutral with regard

Be the First to Write a Review!

Numb (C29G11) Rabbit mAb

Numb (C29G11) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (44)

Reviews

Numb (C29G11) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map