Integrin alpha5 Antibody 4705S from Cell Signaling Technology

Product Specs
ItemIntegrin alpha5 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4705S
Quantity100 µl
ApplicationsW
ReactivityH, M, Mk
TargetITGA5
HostRabbit
NCBI Gene AliasesCD49e, FNRA, VLA-5, VLA5A
NCBI Full Gene Nameintegrin subunit alpha 5
ClonalityPolyclonal
Research AreaAdhesion/ECM
Molecular Weight150

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Rnd3 regulates lung cancer cell invasion and migration independently of ROCK1 signaling via alpha 5 integrin modulationLife Science AllianceMay 1, 2026Noemi Garcia Garcia, Thanh Ha Vy Nguyen, Dane Richey, Emily F Cox, Jon Coca Juaristi, Cody Ashby, Analiz Rodriguez, Katie R Ryanfollows: Rnd3 (3664), ROCK1 (4035), RhoA (2117) pMLC2 (3671), pCofilin (3313), Cofilin (5175), alpha 5 (4705), alpha V (4711), beta 1 (9699), beta 3 (13166), beta 5 (3629) integrins, and tubulin (2146) (Cell Signaling Technology

(2) Magnetic-Assisted Aptamer Selection and Isolation of Migrasomes for Application in Lung Adenocarcinoma Proteomic AnalysisJ Extracell VesiclesApril 17, 2026Yixin Xu, Lin Jiao, Qiangying Yi, Yuzuo Chen, Bei Cai, Junlong Zhang, Zhuochun Huang, Yao Luo, Yanjun Si, Yao Wu, et al.ab201693, 1: 2000), NDST1 (Sigma‐Aldrich, SAB1307040, 1: 1000), ITGA5 (Cell Signaling Technology, #4705, 1:1000), TSG101 (Abcam, ab125011, 1:1000), ALIX (Abcam, ab186429, 1:1000), CD63 (Abcam, ab68418;1: 800

(3) Redox regulation of cell migration via Nischarin S-glutathionylationFree Radical Biology and MedicineFebruary 1, 2026Madhu C. Shivamadhu, Dhanushika S.K. Kukulage, Rayavarapu Padmavathi, Daniel Oppong, Faezeh Mashhadi Ramezani, Denaye N. Eldershaw, Brett M. Collins, Young-Hoon AhnSignaling, Cat# 9211S), p38 (1:1000; Cell Signaling, Cat# 9212S), Integrin α−5 (Cell Signaling, Cat# 4705S), GSTO1/2 (1:1000; Santa Cruz, Cat# sc-166040), GSTP (1:1000; MBL Life Science, Cat# 311-H), Glrx3 (1:1000;

(4) A switch from α5β1 to αvβ3 integrin activity contributes to the development of a profibrotic mesenchymal phenotype in trabecular meshwork cellsFrontiers in Cell and Developmental BiologyJanuary 30, 2026Kassidy L. Johns, Jennifer A. Faralli, Mark S. Filla, Nandini Shah, Kate E. Keller, Donna M. Peterstemperature. Primary antibodies used were rabbit anti-α5 integrin (Cell Signaling Technology, Cat # 4705S, RRID:AB_2233962, 1:1000), rabbit anti-αSMA (Abcam, #ab5694; RRID: AB_2223021), 1:250, rabbit anti-β3

(5) Targeting TCF21-TCF3 heterodimer in tumor-associated pericytes attenuates hematogenous metastasis by restoring pericyte gatekeeper functionCell Reports MedicineJanuary 20, 2026Wenqian Yin, Haiqin Yao, Xiaobo Li, Wenxuan Pan, Yikan Zhang, Chenran Wang, Lijuan Deng, Changwei Lin, Zhi-Min Zhang, Jinghua Pan, et al.AB_2941910" Laminin,Abcam,"Cat#: ab11575,RRID: AB_298179" Integrin α5,Cell Signaling Technology,"Cat#: 4705S,RRID: AB_2233962" VWF,Abcam,"Cat#: ab11713,RRID: AB_298501" α-SMA,Cell Signaling Technology,"Cat#:

(6) O-GlcNAcylation of AMFR stabilizes TSPAN4 to regulate migrasome formation for viral releaseNature CommunicationsJanuary 7, 2026Linghui Yu, Jiajia Li, Yiyang Han, Xiao Yang, Yu Fu, Weiyi Zhang, Yaming Jiu, Linling Cheng, Binbin DingRabbit anti-HA (3724, WB 1:1000), rabbit anti-Rab11 (5589, WB 1:2000), and rabbit anti-Integrin α5 (4705, WB 1:1000) were obtained from Cell Signaling Technology. Mouse anti-Tubulin (E7, WB 1:10000) was obtained

(7) Ly6/uPAR Protein from Asterias rubens Starfish Stimulates Migration and Invasion of Human Epithelial and Immune CellsMarine DrugsDecember 19, 2025Ekaterina N. Lyukmanova, Tamara Y. Gornostaeva, Sergey V. Shabelnikov, Zakhar O. Shenkarev, Mikhail P. Kirpichnikov, Alexander S. Paramonov, Maxim L. Bychkovintegrin subunits bound to nAChRs were detected with the following rabbit primary antibodies: α5 integrin (4705, Cell Signaling, Danvers, MA, USA, 1:10,000), αV integrin (4711, Cell Signaling, 1:10,000), β1 integrin

(8) Engineered migrasomes provide a robust and thermally stable vaccination platformElifeNovember 13, 2025Dongju Wang, Haifang Wang, Wei Wan, Zihui Zhu, Takami Sho, Yi Zheng, Xing Zhang, Longyu Dou, Qiang Ding, Li Yu, et al.ChemiDoc MP Imaging System (Bio-Rad). Primary antibodies used for immunoblotting included anti-integrin α5 (CST, 4705T), anti-Na-K-ATPase (CST, 3010S), anti-histone H3 (CST, 4499S), anti-lamp2 (Sigma), anti-calnexin (abcam,

(9) Passive hydrotherapy preserves cartilage and muscle integrity in a murine osteoarthritis model: potential role of integrin αV/TGF-β mechanotransductionFrontiers in PhysiologyOctober 29, 2025Wu Di, Wang Songyang, Feng Ruibing, Huang Yong, Hu Hao, Duan Xiaofeng, Rong Yang, Dong Yunxiang, Wu Gangincubated with the membranes overnight at 4 °C (Antibody integrin β1, 1:1000, 4706S; integrin α5, 1:1000, 4705T; integrin αV, 1:1000, 4711T, CST, United States of America. Antibody integrin α7, 1:2500, ab203254,

(10) Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with lamininJ Cell BiolJune 2, 2025Tatsuki Isogai, Koichiro M. Hirosawa, Miki Kanno, Ayano Sho, Rinshi S. Kasai, Naoko Komura, Hiromune Ando, Keiko Furukawa, Yuhsuke Ohmi, Koichi Furukawa, et al.polyclonal anti-integrin α3 (1:500, Cat# ab190731; Abcam), rabbit polyclonal anti-integrin α5 (1:250, Cat# 4705S; Cell Signaling), rabbit monoclonal anti-integrin α5 clone EPR7854 (1:500, Cat# ab150361; Abcam), rabbit

(11) Luminescent sensing of conformational integrin activation in living cellsCell RepFebruary 25, 2025Giulia Villari, Noemi Gioelli, Marta Gino, Heng Zhang, Kelly Hodge, Francesca Cordero, Sara Zanivan, Jieqing Zhu, Guido Seriniintegrin (IP),BD Pharmingen,Cat#555650; RRID:AB_2233951 Rabbit anti-α5 integrin (WB),Cell Signaling,Cat#4705S Mouse anti-α2 integrin (IP/WB),Santa Cruz,Cat#sc-74466; Clone: C-9; RRID:AB_1124939 Rabbit anti- αv

(12) Mitsugumin 53 Inhibits Angiogenesis Through Regulating Focal Adhesion Turnover and Tip Cell FormationJ Cell Mol MedFebruary 24, 2025Shuangshuang Yuan, Qin Yu, Tangting Chen, Tian Li, Yongjie Li, Xin Deng, Ni Chen, Jingcan You, Rong Li, Yan Liu, et al.(#48453), Rab7 (#95746), LAMP1 (15665), total integrin β1 (#9699), integrin β3 (#4702) and integrin α5 (#4705) were obtained from Cell Signalling Technology (Beverly, MA, USA). Antibodies to β‐actin (#AA128) and

(13) Packaged release and targeted delivery of cytokines by migrasomes in circulationCell DiscoveryDecember 9, 2024Haifeng Jiao, Xiaopeng Li, Ying Li, Ziyi Guo, Yuzhuo Yang, Yiqun Luo, Xiaoyu Hu, Li Yu(#6975), anti-Rab11 (#5589), anti-VAMP2 (#13508), anti-TNF-α (#11948), anti-IL-6 (#12912), anti-Itg α5 (#4705) and anti-Alix (#92880) antibodies were from Cell Signaling Technology. Anti-Cellubrevin (#ET7108-31),

(14) The USP12/46 deubiquitinases protect integrins from ESCRT-mediated lysosomal degradationEMBO ReportsNovember 6, 2024Kaikai Yu, Guan M Wang, Shiny Shengzhen Guo, Florian Bassermann, Reinhard Fässlervectors,Addgene,#43974 Antibodies,Antibodies,Antibodies Rabbit anti-α5 integrin,Cell Signaling Technology,#4705 Mouse anti-human β1 integrin,BD biosciences,Clone 18 Rabbit anti-mouse β1 integrin,"Azimifar et al,

(15) Localized, highly efficient secretion of signaling proteins by migrasomesCell researchAugust 1, 2024Jiao H, Li X, Li Y, Guo Y, Hu X, Sho T, Luo Y, Wang J, Cao H, Du W, et al.(#3402), anti-Rab8a (#6975), anti-Rab10 (#8127), anti-Rab11 (#5589), anti-VAMP2 (#13508), anti-Itg α5 (#4705) and anti-Itg β1 (#4706) antibodies were from Cell Signaling Technology. Anti-Cellubrevin (#ET7108-31)

(16) CD151-enriched migrasomes mediate hepatocellular carcinoma invasion by conditioning cancer cells and promoting angiogenesisJournal of Experimental & Clinical Cancer ResearchJune 6, 2024Kangnan Zhang, Zhenhua Zhu, Rongrong Jia, N A Wang, Min Shi, Yugang Wang, Shihao Xiang, Qinghui Zhang, Ling Xu(1:1000, ab181995, Abcam, USA), TSPAN7 (1:1000, 18695-1-AP, Proteintech, USA), Integrin α5 (1:1000, 4705, Cell Signaling Technology, USA), PIGK (1:1000, ab201693, Abcam, USA), PGCP (CPQ) (1:1000, ab96159,

(17) Quantification of urinary podocyte-derived migrasomes for the diagnosis of kidney diseaseJournal of extracellular vesiclesJune 1, 2024Yang R, Zhang H, Chen S, Lou K, Zhou M, Zhang M, Lu R, Zheng C, Li L, Chen Q, et al.anti‐PIGK (Abcam, ab201693), anti‐TSPAN4 (Abcam, ab181995), anti‐ITGA5 (Cell Signaling Technology, 4705T), anti‐APOB (Abcam, ab20737) and anti‐PLA2R (Abcam, ab211490). All primary antibodies were used in dilution

(18) A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cellsCommunications biologyMay 24, 2024Benwell CJ, Johnson RT, Taylor JAGE, Lambert J, Robinson SD.and reagents The following primary antibodies were used for experimental analyses: α5 integrin (CST: 4705S, RRID: AB_2233962, 1:1000; Ab25251, RRID: AB_448738, 1:200), β-actin (CST: 8457S, RRID: AB_10950489,

(19) Antibody–Drug Conjugate αEGFR-E-P125A Reduces Triple-negative Breast Cancer Vasculogenic Mimicry, Motility, and Metastasis through Inhibition of EGFR, Integrin, and FAK/STAT3 SignalingCancer Res CommunMarch 11, 2024Ankita P. Sankar, Hyun-Mi Cho, Seung-Uon Shin, Tal Sneh, Sundaram Ramakrishnan, Christian Elledge, Yu Zhang, Rathin Das, Hava Gil-Henn, Joseph D. Rosenblattimmunoprecipitated using 1 mg of cell lysate and α5 integrin antibody (Cell Signaling Technology, catalog no. 4705S) according to the manufacturer's instructions. The resulting IP eluate was used for Western blot analysis. Scratch

(20) Antibody-drug conjugate αEGFR-E-P125A reduces triple-negative breast cancer vasculogenic mimicry, motility, and metastasis through inhibition of EGFR, integrin, and FAK/STAT3 signalingCancer Research CommunicationsMarch 11, 2024Ankita P. Sankar, Hyun-Mi Cho, Seung-Uon Shin, Tal Sneh, Sundaram Ramakrishnan, Christian Elledge, Yu Zhang, Rathin Das, Hava Gil-Henn, Joseph D. Rosenblattimmunoprecipitated using 1 mg of cell lysate and α5 integrin antibody (Cell Signaling Technology, catalog no. 4705S) according to the manufacturer's instructions. The resulting IP eluate was used for Western blot analysis. Scratch

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Integrin alpha5 Antibody

Integrin alpha5 Antibody from Cell Signaling Technology

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Cell Signaling Technology

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Integrin alpha5 Antibody from Cell Signaling Technology

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