PKCepsilon (22B10) Rabbit mAb 2683S from Cell Signaling Technology

Product Specs
ItemPKCepsilon (22B10) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2683S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
TargetPKCepsilon
HostRabbit
NCBI Gene AliasesPKCE, nPKC-epsilon
ClonalityMonoclonal
NCBI Full Gene Nameprotein kinase C epsilon
Research AreaCa, cAMP and Lipid Signaling
Clone22B10
Molecular Weight82

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) High-speed multiplexed DNA-PAINT imaging of nuclear organization using an expanded sequence repertoireNat CommunApril 22, 2026Abhinav Banerjee, Micky Anand, Mansi Srivastava, Vedanth Shree Vidwath, Mahipal Ganjicomparison (Supplementary Data 3). For imaging the nucleolus, primary antibody against Fibrillarin (CST #2683 T) was added to mock cells in antibody incubation buffer for 1 h. The sample was washed five times with

(2) Norepinephrine inhibits cell cycle re-entry of neonatal rat ventricular cardiomyocytes characterized by the absence of de novo nestin expressionPhysiol RepJuly 30, 2025Adrien Aubry, Mariana Kebbe, Aya Al-Katat, Louis Villeneuve, Angelino Calderoneanti‐PKC‐δ (1:2000, catalogue #2058; Cell Signaling), rabbit polyclonal anti‐PKC‐ε (1:2000, catalogue #2683; Cell Signaling), and a mouse monoclonal anti‐GAPDH (1:10,000, RRID:AB_437392; Ambion, Austin, TX).

(3) Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathwayeLifeFebruary 11, 2025Mu Y, Hu S, Liu X, Tang X, Lin J, Shi H.RRID:AB_11178792",IF(1:400) antibody,PKCε (22B10)(Rabbit monoclonal),Cell Signaling Technology,"Cat# 2683, RRID:AB_2171906","IF(1:400, TSA)" antibody,PKC eta (EPR18513)(Rabbit monoclonal),Abcam,"Cat# ab179524,

(4) Optogenetic control of Protein Kinase C-epsilon activity reveals its intrinsic signaling properties with spatiotemporal resolutionbioRxivJanuary 6, 2025Qunxiang Ong, Crystal Jing Yi Yi Lim, Yilie Liao, Justin Tze-Yang Tze-Yang Ng, Ler Ting Rachel Rachel Lim, Shernys Xuan Yi Yi Koh, Sher En En Chan, Pheobe Yu Ying Yu Ying, Huijun Lim, Chen Rui Ye, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies PKC epsilon monoclonal anti-Rabbit,Cell Signalling Technology,#2683 Phospho-(Ser) PKC substrate polyclonal anti-Rabbit,Cell Signalling Technology,#2261 Insulin Rb antibody

(5) Neuropeptide FF Promotes Neuronal Survival and Enhances Synaptic Protein Expression Following Ischemic InjuryInternational journal of molecular sciencesOctober 28, 2024Choi IA, Yun JH, Lee J, Choi DH.synaptophysin (611880; BD Biosciences, San Jose, CA, USA), BDNF (ab108319; abcam, Cambridge, UK), PKCε (2683; Cell Signaling Technology, Danvers, MA, USA), Phospho-PKCε (NBP3-13312; Novus, Centennial, CO, USA),

(6) Transient receptor potential ankyrin 1 channel modulates the abuse-related mechanisms of methamphetamine through interaction with dopamine transporterBritish journal of pharmacologyAugust 1, 2024Hur KH, Lee Y, Donio AL, Kim SK, Lee BR, Seo JY, Kundu D, Kim KM, Kohut SJ, Lee SY, et al.USA, Cat# 4782, RRID:AB_2170170), PKC (1:1,000, Cell Signalling Technology, Danvers, MA, USA, Cat# 2683, RRID:AB_2171906), TH (1:2000, Cell Signalling Technology, Danvers, MA, USA, Cat# 2792, RRID:AB_2303165),

(7) MicroRNA‑223 overexpression suppresses protein kinase C ε expression in human leukemia stem cell‑like KG‑1a cellsMolecular and Clinical OncologyMay 28, 2024Mallika Osiriphan, Charapat Insukhin, Songyot Anuchapreeda, Pinyaphat Khamphikham, Suwit Duangmanoovernight incubation at 4˚C with primary rabbit antibody targeting PKCε (1:1,000 dilution; cat. no. 2683; Cell Signaling Technology, Inc.) or for 1 h at room temperature with primary rabbit antibody targeting

(8) Ovarian PERK/NRF2/CX43/StAR/progesterone pathway activation mediates female reproductive dysfunction induced by cold exposureScientific ReportsMay 4, 2024Mengnan Ding, Yarong Lu, Qing Wen, Chen Xing, Xin Huang, Yifan Zhang, Wei Wang, Chongchong Zhang, Min Zhang, Fanfei Meng, et al.in this study included p-PERK (1:1000, Abclonal, AP0886), PERK (1:1000, Cell Signaling Technology, 2683), p-NRF2 (1:1000, Affinity, DF7519), NRF2 (1:1000, Cell Signaling Technology, 12721), p-STAT3 (1:1000,

(9) A high‐fat diet supplemented with medium‐chain triglycerides ameliorates hepatic steatosis by reducing ceramide and diacylglycerol accumulation in miceExperimental PhysiologyMarch 1, 2024Stephanie Mourad, Abdualrahman Mohammed Abdualkader, Xiaobei Li, Shailee Jani, Rolando B. Ceddia, Rami Al Batranwas incubated overnight at 4°C with antibodies against PKCε (1:1000, Cell Signaling, catalogue number 2683S), Na+,K+‐ATPase (1:1000, Cell Signaling, catalogue number 3010S) and heat shock protein 90 (HSP90; 1:2000,

(10) Restraint stress promotes nonalcoholic steatohepatitis by regulating the farnesoid X receptor/NLRP3 signaling pathwayActa Biochimica et Biophysica SinicaNovember 24, 2023Fan Yang, Xi-Ting Lv, Xiao-Li Lin, Ruo-Hong Wang, Shu-Mei Wang, Guo-En Wangvolume:beads volume) by a four-dimensional rotary mixer for 30 min at 4°C. After centrifugation at 2683 g for 10 min, each supernatant was divided into three groups: the input group, IP group, and IgG group.

(11) Apelin receptor inhibition in ischemia-reperfused mouse hearts protected by endogenous n-3 polyunsaturated fatty acidsFrontiers in PharmacologyOctober 24, 2023Shuang Zheng, Weijiang Tan, Xiang Li, Lijing Wang, Caiyi Zhu, W. Glen Pyle, Jianxin Chen, Jian Wu, Xuecong Ren, Honghua Chen, et al.Cell Signaling Technology (Danvers, United States). The primary antibodies included antibodies against PKCδ (#9616), PKCε (#2683), p-p38α (Thr180/Tyr182; #4511), t-p38α (#9212), p-PI3K (Tyr458; #4228), t-PI3K (#4257), p-AKT (Ser473;

(12) Augmentation of Cathepsin Isoforms in Diabetic db/db Mouse Kidneys Is Associated with an Increase in Renal MARCKS Expression and ProteolysisInternational journal of molecular sciencesAugust 5, 2023Gholam MF, Bala N, Dogan YE, Alli AA.,Cell Signaling Technologies,2056 PKC delta,WB,Cell Signaling Technologies,9616 PKC epsilon,WB,Cell Signaling Technologies,2683 KLK1,WB,Boster Biological Technology,PA1709 PLCβ3,WB,Cell Signaling Technologies,14247 PLCγ1,"WB,

(13) Evidence for Angiotensin II as a Naturally Existing Suppressor for the Guanylyl Cyclase A Receptor and Cyclic GMP GenerationInternational journal of molecular sciencesMay 10, 2023Ma X, Iyer SR, Ma X, Reginauld SH, Chen Y, Pan S, Zheng Y, Moroni DG, Yu Y, Zhang L, et al.anti-PKCα (catalog#2056, Cell Signaling Technology, Danvers, MA, USA) at 1:500 dilution, anti-PKCε (catalog#2683, Cell Signaling Technology, Danvers, MA, USA) at 1:1000 dilution, anti-Phospho-(Ser) PKC Substrate (catalog#2261,

(14) Integrin β1/FAK/SRC signal pathway is involved in autism spectrum disorder in Tspan7 knockout ratsLife science allianceMarch 1, 2023Pang S, Luo Z, Dong W, Gao S, Chen W, Liu N, Zhang X, Gao X, Li J, Gao K, et al.1:1,000; CST), ERK (9102; dilution of 1:1,000; CST), p-PKCε (ab63387; dilution of 1:500; Abcam), PKC; (2683; dilution of 1:500; CST), p-PKCα (9375; dilution of 1:1,000; CST), PKCα (2056; dilution of 1:500; CST),

(15) PKCε inhibition prevents ischemia‑induced dendritic spine impairment in cultured primary neuronsExperimental and Therapeutic MedicineFebruary 16, 2023Chenjie Ge, Xuefeng Wang, Yunhong Wang, Lilei Lei, Guohua Song, Mincai Qian, Shiliang Wanganti-β Tubulin (cat. no. 2416; 1:5,000, Cell Signaling Technology, Inc.), and rabbit anti-PKCε (cat. no. 2683; 1:1,000; Cell Signaling Technology, Inc.). The secondary antibodies were horseradish peroxidase anti-rabbit

(16) EVIDENCE FOR ANGIOTENSIN II AS A NATURALLY EXISTING SUPPRESSOR FOR THE NATRIURETIC PEPTIDE SYSTEMbioRxiv : the preprint server for biologyJanuary 27, 2023Ma X, Iyer SR, Ma X, Reginauld SH, Chen Y, Pan S, Zheng Y, Moroni D, Yu Y, Zhang L, et al.anti-PKCα (catalog#2056, Cell Signaling Technology, Danvers, MA) at 1:500 dilution, anti-PKCε (catalog#2683, Cell Signaling Technology, Danvers, MA) at 1:1000 dilution, anti-Phspho-(Ser) PKC Substrate (catalog#2261,

(17) Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C isozymes are involved in mGlu(5a) receptor internalizationThe Journal of biological chemistryOctober 1, 2022van Senten JR, Møller TC, Moo EV, Seiersen SD, Bräuner-Osborne H.(Cell Signaling Technology Cat# 46809, RRID:AB_2799309) and anti-PKCε (Cell Signaling Technology Cat# 2683, RRID:AB_2171906) antibodies were bought from Cell Signal Technology. Anti-GAPDH (Novus Cat# NB600-502,

(18) Involvement of the Voltage-Gated Calcium Channels L- P/Q- and N-Types in Synapse Elimination During Neuromuscular Junction DevelopmentMolecular NeurobiologyJuly 1, 2022Neus Garcia, Pablo Hernández, Maria A. Lanuza, Marta Tomàs, Víctor Cilleros-Mañé, Laia Just-Borràs, Maria Duran-Vigara, Aleksandra Polishchuk, Marta Balanyà-Segura, Josep Tomàs(1:1000; ≠ 13414, Cell Signalling Technology; Massachusetts, USA), and rabbit anti-PKCε (1:1000; ≠ 2683, Cell Signalling Technology; Massachusetts, USA)). Horseradish peroxidase-conjugated secondary antibody

(19) HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCε ActivationAntioxidants (Basel)February 14, 2022Daniele Mancardi, Pasquale Pagliaro, Lisa A. Ridnour, Carlo G. Tocchetti, Katrina Miranda, Magdalena Juhaszova, Steven J. Sollott, David A. Wink, Nazareno PaolocciPKCε (primary and secondary antibodies were purchased from Cell Signaling—Na+/K+-ATPase 3010, PKCε 2683, Actin 4968—and diluted according to manufacturer’s instruction). 2.4. Immunohistochemistry Preparation Samples

(20) Dexmedetomidine Promotes Lipopolysaccharide-Induced Differentiation of Cardiac Fibroblasts and Collagen I/III Synthesis through α(2A) Adrenoreceptor-Mediated Activation of the PKC-p38-Smad2/3 Signaling Pathway in MiceInternational journal of molecular sciencesNovember 25, 2021Liao J, Li K, Su X, Chen Y, Wang Y, Tang X, Xing Y, Xu Y, Dai X, Teng J, et al.from Abcam (Cambridge, UK). Antibodies against vimentin (#5741), p38 (#9212S), p-p38 (#4511S), PKC (2683S) and GAPDH (#2118) were purchased from Cell Signaling Technology, Inc. (Beverly, MA, USA). Antibodies

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PKCepsilon (22B10) Rabbit mAb

PKCepsilon (22B10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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PKCepsilon (22B10) Rabbit mAb from Cell Signaling Technology

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