Csk (C74C1) Rabbit mAb 4980S from Cell Signaling Technology

Product Specs
ItemCsk (C74C1) Rabbit mAb
CompanyCell Signaling Technology
Price $399.00 Inquire
Catalog Number4980S
Quantity100 µl
ApplicationsW, W-S
ReactivityH, M, R, Mk, Pg
TargetCsk
HostRabbit
ClonalityMonoclonal
NCBI Full Gene NameC-terminal Src kinase
Research AreaMAP Kinase Signaling
IsotypeIgG
CloneC74C1
Molecular Weight50

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) SHP2 regulates VEGFR2 Y1175/PLCγ signaling to impair tumor endothelial barrier stabilityiScienceFebruary 20, 2026Polina Kremmyda, Sara Owad, Sagnik Pal, Elvira Wildheim, Catarina Chanoca, Cecilia Lindskog, Elin SjöbergAB_2063006 Rat anti-mouse CD45,BD Pharmingen,553076; RRID: AB_394606 Rabbit anti-CSK,Cell Signaling Technology,4980S; RRID: AB_2276592 Mouse anti-CSK,Invitrogen Thermo Fisher,MA5-15707; RRID: AB_10981163 Mouse anti-phospho-eNOS

(2) SHP2 is essential for the progesterone-promoted proliferation and migration in breast cancer cell linesFront Endocrinol (Lausanne)February 10, 2025Hui-Chen Wang, Wen-Sen LeeSanta Cruz Biotechnology, Inc. (Santa Cruz, CA). Anti-cSrc (#2109), anti-p-cSrcY416 (#2101), anti-p-cSrcY527 (#2105), anti-Csk (#4980), anti-caveolin-1 (#3267), anti-p-caveolin-1 (#3251), anti-p140Cap (#3757) and anti-SHP2 (#9793) antibodies

(3) Ligand-induced segregation from large cell-surface phosphatases is a critical step in γδ TCR triggeringCell reportsSeptember 24, 2024Li F, Roy S, Niculcea J, Gould K, Adams EJ, van der Merwe PA, Choudhuri K.pSrc(Tyr416),Cell Signaling Technology,Cat #: 6943 Anti-mouse CSK,Cell Signaling Technology,Cat #: 4980 Anti-human pLAT (Tyr191),Cell Signaling Technology,Cat #: 3584 Anti-β-actin,Cell Signaling Technology,Cat

(4) Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomasCancer CellMay 13, 2024Jaewoo Choi, Michele Ceribelli, James D. Phelan, Björn Häupl, Da Wei Huang, George W. Wright, Tony Hsiao, Vivian Morris, Francesco Ciccarese, Boya Wang, et al.RRID:AB_10694080 Ubiquitin,Santa Cruz,Cat.# SC-8017; RRID:AB_628423 CSK,Cell Signaling Technology,Cat.# 4980; RRID:AB_2276592 p-SRC family (Y416),Cell Signaling Technology,Cat.# 6943; RRID:AB_10013641 p-SYK

(5) Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating LckJournal of biomedical scienceMarch 27, 2024Chyuan IT, Liao HJ, Tan TH, Chuang HC, Chu YC, Pan MH, Wu CS, Chu CL, Sheu BC, Hsu PN.anti-p-SHP-2 (Y580, catalog no. 3703S), anti-CBL (catalog no. 2747S), anti-CSK (C74C1, catalog no. 4980), and anti-FLAG (DYKDDDDK Tag Antibody, catalog no. 2368) antibodies were purchased from Cell Signaling Technology

(6) Ibrutinib-induced pulmonary angiotensin-converting enzyme activation promotes atrial fibrillation in ratsiScienceFebruary 16, 2024Sen Yan, Wei Xu, Ning Fang, Luyifei Li, Ning Yang, Xinbo Zhao, Hongting Hao, Yun Zhang, Qian Liang, Zhiqi Wang, et al.anti-ACE,Abcam,Ca#ab254222;RRID_AB_3073965 Rabbit monoclonal anti-CSK(C74C1),Cell Signaling Technology,Ca#4980;RRID_AB_2276592 Rabbit monoclonal anti-Src,Cell Signaling Technology,Ca#2108;RRID_AB_331137 Rabbit

(7) The c‐Src/LIST Positive Feedback Loop Sustains Tumor Progression and ChemoresistanceAdvanced ScienceJuly 1, 2023Xianteng Wang, Bing Wang, Fang Li, Xingkai Li, Ting Guo, Yushun Gao, Dawei Wang, Weiren Huangab290), anti‐P65 (1:3000, ab16502), anti‐P65 (phospho S536) (1:1000, ab76302), anti‐CSK (1:1000, CST, 4980), anti‐CHK (1:1000, CST, 2360), anti‐Cav1 (phospho Y14) (1:1000, CST, 3251), anti‐Cav1 (1:1000, ab2910),

(8) Novel Therapeutic Potentials of Taxifolin for Obesity-Induced Hepatic Steatosis, Fibrogenesis, and TumorigenesisNutrientsJanuary 10, 2023Takayuki Inoue, Bin Fu, Miwako Nishio, Miyako Tanaka, Hisashi Kato, Masashi Tanaka, Michiko Itoh, Hajime Yamakage, Kozue Ochi, Ayaka Ito, et al.(diluted 1:1000; #2794; CST), anti-TNFα (diluted 1:800; #11948; CST), and anti-β-actin (diluted 1:3000; #4980; CST). After washing, each band was incubated with an HRP-conjugated anti-rabbit IgG secondary antibody

(9) Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cellsMolecular oncologyJanuary 1, 2022Hühn D, Martí-Rodrigo P, Mouron S, Hansel C, Tschapalda K, Porebski B, Häggblad M, Lidemalm L, Quintela-Fandino M, Carreras-Puigvert J, et al.4 °C with antibodies against PD‐L1 (CST, 13684), ERα (CST, 8644), C‐terminal SRC kinase (CSK; CST, 4980), Stat1 (CST, 14994), phospho‐Stat1Tyr701 (CST, 9167), p65 (CST, 8242), phospho‐p65Ser536 (CST, 3033),

(10) A novel treatment strategy for lapatinib resistance in a subset of HER2-amplified gastric cancerBMC CancerDecember 1, 2021Gang Ning et al.Tween-20). Then, the membranes were incubated with primary antibodies overnight at 4 °C. CSK antibody (#4980), PTEN antibody (#9188), MAPK1/2 antibody (#9102), Phospho-MAPK1/2 (Thr202/Tyr204) antibody (#4370),

(11) Inhibition of Cathepsin K Alleviates Autophagy-Related Inflammation in Periodontitis-Aggravating ArthritisInfection and immunityNovember 16, 2020Yue Y, Yin W, Yang Q, Ren J, Tan L, Wang J, Liu J, Lu Q, Ding H, Zhan W, et al.The primary antibodies used were speciﬁc for TFEB, CTSK, LC3A/B, and GAPDH (catalog numbers 32361, 4980, 12741, and 5174, respectively; Cell Signaling Technology). Statistical analysis. Data are shown as

(12) SCIMP is a universal Toll‐like receptor adaptor in macrophagesJournal of Leukocyte BiologyFebruary 1, 2020Lin Luo, James E. B. Curson, Liping Liu, Adam A. Wall, Neeraj Tuladhar, Richard M. Lucas, Matthew J. Sweet, Jennifer L. Stowdescribed (12). Antibodies to p-ERK1/2 (4370), p-Akt (9271), p-IκBα (2859), p-TBK1/NAK (5483), Csk (4980), GAPDH (2118), Grb2 (3972), Lyn (2796), SLP65 (12168), Myc (2276), p-Tyrosine (9411) and the p-Src

(13) Inhibition of Ctsk modulates periodontitis with arthritis via downregulation of TLR9 and autophagyCell ProliferationJanuary 1, 2020Wei Wei, Jie Ren, Wuwei Yin, Handong Ding, Qiuyu Lu, Liangyu Tan, Shibing Deng, Jie Liu, Qin Yang, Jiajia Wang, et al.blotted with specific primary antibodies, TLR9, TFEB, CTSK, LC3A/B and GAPDH (Cat#13674, Cat#32361, Cat#4980, Cat#12741, Cat#5174, respectively, Cell Signaling Technology). According to the manufacturer's instructions,

(14) Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophyNature communicationsSeptember 19, 2019Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, Noda S, Murakami A, Onodera K, Okada Y, et al.Cell Signaling Technology) cleaved caspase3 (Asp175) (#9661, 1:1000; Cell Signaling Technology) and Csk (#4980, 1:2000; Cell Signaling Technology). Primary antibodies bound to the proteins were probed with a 1:5000

(15) SUMOylation of Csk Negatively Modulates its Tumor Suppressor FunctionNeoplasia (New York, N.Y.)July 1, 2019Cui N, Liu T, Guo Y, Dou J, Yang Q, Zhang H, Chen R, Wang Y, Zhao X, Yu J, et al.phosphorylation on c-Src. Materials and Methods Antibodies and Reagents Antibodies against Csk (#2109 and #4980), phospho-Src (Tyr 416) (#2101; used for detecting human Src pY419), phospho-Src (Tyr 527) (#2105; used

(16) A functional CRISPR/Cas9 screen identifies kinases that modulate FGFR inhibitor response in gastric cancerOncogenesisMay 10, 2019Chen J, Bell J, Lau BT, Whittaker T, Stapleton D, Ji HP.cells. Cells were transfected with 10 nmol/l oligos and were harvested 72 h. ILK (#3856) and CSK (#4980) antibodies were obtained from Cell Signaling. Vinculin (#13901, Cell Signaling) was the loading control.

(17) Biodiesel by Transesterification of Rapeseed Oil Using Ultrasound: A Kinetic Study of Base-Catalysed ReactionsEnergiesAugust 25, 2018JosÃ© Encinar, Ana Pardal, Nuria SÃ¡nchez, Sergio Nogales(±1.7) (±0.7)(± 70 (± 94.0 866.2 3(±1.3) 4.8 (±0.1) 4.8 cSt (±0.2) kg/m 70 (±2) 93.6 (±1.0) 866.5 (±0.9) 4.4 (±0.1) 4980 (±2) 55.6 (±1.1) (±2.1) 8.8 ((±0.3) (±1) 70.8 (±1.3) 879.4 875.5 (±1.4) 6.9 ±0.2) (±1) 97.4 (±1.2) 872.0 870.9 (±0.8) 4.9

(18) Broad-Spectrum Regulation of Nonreceptor Tyrosine Kinases by the Bacterial ADP-Ribosyltransferase EspJmBioMay 2, 2018Dominic J. Pollard, Cedric N. Berger, Ernest C. So, Lu Yu, Kate Hadavizadeh, Patricia Jennings, Edward W. Tate, Jyoti S. Choudhary, Gad FrankelPY20",Sigma-Aldrich,"Catalog no. P4110, RRID AB_477342" "Csk, rabbit monoclonal C74C1",Cell signaling technology,"Catalog no. 4980S, RRID AB_2276592" "GFP, mouse monoclonal 9F9.F9","Abcam, Inc.","Catalog no. ab1218, RRID AB_298911" "GFP,

(19) Elevated (Pro)renin Receptor Expression Contributes to Maintaining Aerobic Metabolism in Growth Hormone DeficiencyJournal of the Endocrine SocietyMarch 1, 2018Yasufumi Seki, Midori Yatabe, Chikahito Suda, Satoshi Morimoto, Atsuhiro Ichiharaanti-PDH E1 β subunit (PDHB; WH0005162M3, RRID: AB_2236961; Sigma-Aldrich, St. Louis, MO), anti-β-actin (#4980, RRID: AB_2223172; Cell Signaling Technology, Danvers, MA), anti-rabbit IgG (A0545, RRID: AB_257896;

(20) Encoding optical control in LCK kinase to quantitatively investigate its activity in live cellsNature structural & molecular biologyDecember 1, 2017Liaunardy-Jopeace A, Murton BL, Mahesh M, Chin JW, James JR.2101), anti-LCK (cat#: 2657), anti-SHP 1 (cat#: 3759), anti-SHP 2 (cat#: 3397) and anti-CSK mAb (cat#: 4980), which were all purchased from Cell Signaling Technology and are all raised in the rabbit except anti-LCK,

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Csk (C74C1) Rabbit mAb

Csk (C74C1) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Csk (C74C1) Rabbit mAb from Cell Signaling Technology

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