Bassoon Antibody 141 003 from Synaptic Systems GmbH

Product Specs
ItemBassoon Antibody
CompanySynaptic Systems GmbH
Price $475.00Supplier Page View Company Product Page
Catalog Number141 003
Hostrabbit
Quantity50 µg
ApplicationsWB, ICC, IHC, IHC-P, ELISA
Reactivityrat, mouse
TargetBassoon
Clonalitypolyclonal
Purityaffinity purified
ImmunogenRecombinant protein corresponding to AA 3569 to 3769 from rat Bassoon
Antibody TypePrimary antibody
Formatlyophilized

Questions and Answers

Can this antibody be used for immunocytochemistry in neuronal studies?

Yes, the Bassoon antibody has been shown to work in immunocytochemistry applications, as evidenced by its use in studies involving hippocampal neurons where it was utilized to label pre- and postsynaptic structures (see ).

What species does this antibody react with, and has it been used in relevant studies?

The Bassoon antibody is reactive with mouse and rat species. It has been cited in multiple studies, including those investigating synaptic architecture and plasticity in both in vivo and in vitro models (see and ).

What is the recommended dilution for using this antibody in immunohistochemistry?

The recommended dilution for the Bassoon antibody in immunohistochemistry is 1:500, as indicated in various studies that utilized this antibody for staining synaptic proteins (see and ).

Has this antibody been utilized in any advanced imaging techniques?

Yes, the Bassoon antibody has been employed in super-resolution microscopy techniques, which allow for detailed visualization of synaptic structures, as demonstrated in studies focusing on synaptic dynamics and organization (see ).

Synaptic Systems GmbH

Rudolf-Wissell-Str. 28

Goettingen 37079

Germany

Phone: +49-551-50556-0
+49-551-50556-384

Company Profile

Website: http://www.sysy.com/

(1) Synaptic pruning following NMDAR-dependent LTD preferentially affects isolated synapsesiScienceOctober 17, 2025Camus C, Leval L, Villicana-Munoz V, Jelinkova S, Compans B, Gambino F, Herzog E, Choquet D, Hosy E.monoclonal mouse anti-PSD-95 antibody (MA1-046, ThermoFischer), for Bassoon: monoclonal rabbit anti-Bassoon (141003, Synaptic Systems), for Homer 1, monoclonal Guinea Pig (160004, Synaptic Systems); For GFP, monoclonal

(2) Presynaptic Rac1 in the hippocampus selectively regulates working memoryeLifeJuly 24, 2024Kim J, Bustamante E, Sotonyi P, Maxwell N, Parameswaran P, Kent JK, Wetsel WC, Soderblom EJ, Rácz B, Soderling SH.(1:500 for IHC and 1:1000 for WB, Thermo Fisher R960-25), rabbit-anti-Bassoon (1:500, Synaptic Systems 141003), mouse-anti-RFP (1:500, Synaptic Systems 409011), rabbit-anti-Homer1 (1:500, Synaptic Systems 160003),

(3) Instability of excitatory synapses in experimental autoimmune encephalomyelitis and the outcome for excitatory circuit inputs to individual cortical neuronsBrain, Behavior, and ImmunityJuly 1, 2024Rebecca L. Gillani, Eseza N. Kironde, Sara Whiteman, Theodore J. Zwang, Brian J. Bacskaias follows: PSD95 (UC Davis/NIH NeuroMab Facility # 73–028), Bassoon (Synaptic Systems # 141 004 and 141 003), GFP (Thermo Fisher Scientific # A10262). Secondary antibodies were as follows: Goat Anti-Guinea pig

(4) Prolonged Activity Deprivation Causes Pre- and Postsynaptic Compensatory Plasticity at Neocortical Excitatory SynapseseNeuroMay 22, 2024Derek L. Wise, Yasmin Escobedo-Lozoya, Vera Valakh, Emma Y. Gao, Aishwarya Bhonsle, Qian L. Lei, Xinyu Cheng, Samuel B. Greene, Stephen D. Van Hooser, Sacha B. Nelson124-011), VGLUT1 (guinea pig, Synaptic Systems 135 304), and anti-Bassoon (rabbit, Synaptic Systems 141 003). Secondary antibodies were goat anti-mouse Alexa Fluor Plus 555 (Invitrogen A32727), goat anti-guinea pig

(5) Progressive Circuit Hyperexcitability in Mouse Neocortical Slice Cultures with Increasing Duration of Activity SilencingeNeuroApril 23, 2024Derek L. Wise, Samuel B. Greene, Yasmin Escobedo-Lozoya, Stephen D. Van Hooser, Sacha B. Nelsonstain, were anti-PSD-95 (mouse, Synaptic Systems, 124-011), and anti-Bassoon (rabbit, Synaptic Systems, 141-003). Secondary antibodies were goat anti-mouse Alexa Fluor Plus 555 (Invitrogen, A32727) and goat anti-rabbit

(6) Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease modelsThe EMBO journalOctober 4, 2023Rueda-Carrasco J, Sokolova D, Lee SE, Childs T, Jurčáková N, Crowley G, De Schepper S, Ge JZ, Lachica JI, Toomey CE, et al.no.,Company,Host,Dilution Homer1,160006,Synaptic Systems,Chicken,1/200 Synaptotagmin 1/2,105002,Synaptic Systems,Rabbit,1/200 Bassoon,141003,Synaptic Systems,Rabbit,1/200 6E10,803001,BioLegend,Mouse,"1/1,000" 4G8,800708,BioLegend,Mouse,"1/1,000" GAPDH,ab181602,Abcam,Rabbit,"1/20,000" Synaptophysin,ab8049,Abcam,Mouse,"1/1,000" PDS‐95,MAB1596,Merck,Mouse,"1/1,000" PSD‐95,124014,Synaptic Systems

(7) Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokinesScience advancesApril 21, 2023Licht-Murava A, Meadows SM, Palaguachi F, Song SC, Jackvony S, Bram Y, Zhou C, Schwartz RE, Froemke RC, Orr AL, et al.(1:750; Synaptic Systems, #101004; RRID #AB_1210382), rabbit anti-bassoon (1:1000; Synaptic System, #141003; RRID #AB_887697), rabbit anti–red fluorescent protein (1:500; Abcam, #ab34771; RRID # AB_777699), human-specific

(8) Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's diseaseNature neuroscienceMarch 1, 2023De Schepper S, Ge JZ, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH, Kim JS, et al.(Thermo Fisher Scientific, 14-1401-82; Clone APA5, 1/50), rabbit anti-mouse Bassoon (Synaptic System, 141 003; 1/200) and Lyve1 (Abcam, ab14917; 1/500). Secondary antibodies used were a combination of Alexa Fluor

(9) Mapping thalamic innervation to individual L2/3 pyramidal neurons and modeling their ‘readout’ of visual inputNature NeuroscienceMarch 1, 2023Aygul Balcioglu, Rebecca Gillani, Michael Doron, Kendyll Burnell, Taeyun Ku, Alev Erisir, Kwanghun Chung, Idan Segev, Elly NediviVGluT1 (135 302; Synaptic Systems), PSD95 (73–028; UC Davis/NIH NeuroMab Facility), Bassoon (141 004 and 141 003; Synaptic Systems), GFP (A10262; Thermo Fisher Scientific), RFP (600–401-379; Rockland) and Gephyrin

(10) Filamin A organizes γ‑aminobutyric acid type B receptors at the plasma membraneNature communicationsJanuary 3, 2023Jobin ML, Siddig S, Koszegi Z, Lanoiselée Y, Khayenko V, Sungkaworn T, Werner C, Seier K, Misigaiski C, Mantovani G, et al.Life Sciences (NY, USA) (SAP7F407), the Bassoon rabbit polyclonal antibody was from Synaptic Systems (141003), goat Alexa Fluor-532 anti-mouse (A-11002) and goat Alexa Fluor-647 anti-rabbit (A-21245) were from

(11) α-Synuclein induced cholesterol lowering increases tonic and reduces depolarization-evoked synaptic vesicle recycling and glutamate releaseNPJ Parkinson's diseaseJune 7, 2022Lazarevic V, Yang Y, Paslawski W, Svenningsson P.cat. number 142 003); rabbit anti-Bassoon (1:1000; Synaptic Systems, Göttingen, Germany; cat. number 141 003); rabbit anti-RIM 1/2 (1:1000; Synaptic Systems, Göttingen, Germany; cat. number 140 203); rabbit anti-Homer

(12) SRF depletion in early life contributes to social interaction deficits in the adulthoodCellular and molecular life sciences : CMLSMay 4, 2022Roszkowska M, Krysiak A, Majchrowicz L, Nader K, Beroun A, Michaluk P, Pekala M, Jaworski J, Kondrakiewicz L, Puścian A, et al.

(13) Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specificNature communicationsFebruary 17, 2022Hruska M, Cain RE, Dalva MB.Gottingen, Germany, cat# 141 004), rabbit polyclonal anti-Bassoon (1:300, Synaptic Systems, cat #: 141 003), chicken anti-GFP (1:2000, Abcam, Cambridge, MA, cat# ab13970), rabbit monoclonal anti-GluN1 (1:500,

(14) Epitope-preserving magnified analysis of proteome (eMAP)Science advancesNovember 12, 2021Park J, Khan S, Yun DH, Ku T, Villa KL, Lee JE, Zhang Q, Park J, Feng G, Nedivi E, et al.

(15) AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactionsNature communicationsAugust 23, 2021Watson JF, Pinggera A, Ho H, Greger IH.(Sigma-Aldrich, Cat.# H6908, RRID:AB_260070, 1:200, confocal imaging), rabbit anti bassoon (Synaptic Systems Cat# 141 003, RRID:AB_887697, 1:200, STORM imaging) goat anti rabbit IgG AF568 (Thermo Fisher Scientific Cat# A-11036,

(16) Microglial dyshomeostasis drives perineuronal net and synaptic loss in a CSF1R^+/- mouse model of ALSP, which can be rescued via CSF1R inhibitorsScience advancesAugust 1, 2021Arreola MA, Soni N, Crapser JD, Hohsfield LA, Elmore MRP, Matheos DP, Wood MA, Swarup V, Mortazavi A, Green KN.

(17) LOTUS, an endogenous Nogo receptor antagonist, is involved in synapse and memory formationScientific reportsMarch 3, 2021Nishida R, Kawaguchi Y, Matsubayashi J, Ishikawa R, Kida S, Takei K.

(18) TDP-43 proteinopathy impairs mRNP granule mediated postsynaptic translation and mRNA metabolismTheranosticsJanuary 1, 2021Wong CE, Jin LW, Chu YP, Wei WY, Ho PC, Tsai KJ.Chemicon Cat# MAB3119, anti-PSD-95 from Abcam Cat# ab2723, anti-Bassoon from Synaptic Systems Cat# 141003, anti-TDP-43 from Proteintech Cat# 10782-2 AP, anti-FMRP from Cell Signaling Technology Cat# 4317, and

(19) Myosin 18Aα targets the guanine nucleotide exchange factor β-Pix to the dendritic spines of cerebellar Purkinje neurons and promotes spine maturationFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJanuary 1, 2021Alexander CJ, Barzik M, Fujiwara I, Remmert K, Wang YX, Petralia RS, Friedman TB, Hammer JA.18 residues of myosin 18Aα/β (rabbit, 1:50) (55, 66), anti-Bassoon (rabbit, 1:200, Synaptic Systems, 141 003), anti-myosin 2B (rabbit, 1:200, ThermoFisher, PA517026), or anti-β-Pix (mouse, 1:200, BD Biosciences,

(20) SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(-/-) MiceFrontiers in molecular neuroscienceJanuary 1, 2021Lutz AK, Pérez Arévalo A, Ioannidis V, Stirmlinger N, Demestre M, Delorme R, Bourgeron T, Boeckers TM.

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Bassoon Antibody

Bassoon Antibody

Bassoon Antibody

Bassoon Antibody from Synaptic Systems GmbH

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Questions and Answers

Synaptic Systems GmbH

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Bassoon Antibody from Synaptic Systems GmbH

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