HMGA1 (D6A4) XP ® Rabbit mAb 7777S from Cell Signaling Technology

Product Specs
ItemHMGA1 (D6A4) XP ® Rabbit mAb
CompanyCell Signaling Technology
Price $371.00 Inquire
Catalog Number7777S
ApplicationsWB, ICC, IF, IP
ReactivityHu, Mk
Research AreaChromatin Regulation / Nuclear Function
IsotypeIgG
CloneD6A4
Molecular Weight18
NCBI Gene AliasesHMG-R, HMGA1A, HMGIY
NCBI Full Gene Namehigh mobility group AT-hook 1
HostRabbit
TargetHMGA1
ClonalityMonoclonal
Quantity100 µl

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Chemotherapy enhances HMGA1 secretion through the mutant p53-CK2 axis in pancreatic ductal adenocarcinoma cellsCell Death DisOctober 27, 2025Federica Danzi, Giovanna Butera, Damien Sutton, Matthew D. Perricone, Yushu Hu, Adriana Celesia, Marcello Manfredi, Jessica Brandi, Narges Pourmandi, Noah S. Nelson, et al.following primary antibodies were used in this study and at 1:1000 dilution: anti-HMGA1 (Cell Signaling, 7777S), anti-P53 (Cell Signaling, 2527S), anti-pP53 (Ser15) (Cell Signaling, 9286S), anti-phospho-CK2 substrate

(2) C/EBPβ increases tumor aggressiveness by enhancing KIFC1 expression in androgen receptor negative triple negative breast cancerCell Commun SignalMay 30, 2025Shriya Joshi, Chakravarthy Garlapati, Thi Nguyen, Shaligram Sharma, Darshan Shimoga Chandrashekar, Shristi Bhattarai, Sooryanarayana Varambally, Uma Krishnamurti, Xiaoxian Li, Ritu Anejaantibody,"#69,366",Cell Signaling Technology Cyclin B1 antibody,#4138,Cell Signaling Technology HMGA1 (D6A4) antibody,#7777,Cell Signaling Technology Cyclin A2 (BF683),#4656,Cell Signaling Technology Cyclin E antibody,#4129,Cell Signaling Technology

(3) Anti-hsa-miR-59 alleviates premature senescence associated with Hutchinson-Gilford progeria syndrome in miceThe EMBO journalJanuary 4, 2023Hu Q, Zhang N, Sui T, Li G, Wang Z, Liu M, Zhu X, Huang B, Lu J, Li Z, et al.UUCUAAUCCUUGAAGAGUCTT‐3′). The following antibodies were used: antibodies against progerin (ab66587; Abcam); HMGA1 (#7777 for WB; Cell Signaling Technology, ab4078 for ChIP; and ab129153 for IHC; Abcam); HMGA2 (#8179 for WB;

(4) YWHAH activates the HMGA1/PI3K/AKT/mTOR signaling pathway by positively regulating Fra-1 to affect the proliferation of gastric cancer cellsOncology researchJanuary 1, 2023He J, Zeng F, Jin XI, Liang L, Gao M, Li W, Li G, Zhou Y.include: Fra-1 (YM0122,Immunoway, Plano, TX, USA), YWHAH (ab206292, Abcam, Cambridge, MA, USA), HMGA1 (#7777, Cell Signaling Technology, Danvers, MA, USA), PI3K (AF6241, Affinity Biosciences, Cincinnati, OH, USA),

(5) High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X proteinNucleic acids researchFebruary 28, 2022Shen Z, Wu J, Gao Z, Zhang S, Chen J, He J, Guo Y, Deng Q, Xie Y, Liu J, et al.anti-ANXA1(1:3000, A0249), anti-mouse HMGA1 (1:3000, A4343) from Abclonal; anti-human HMGA1 (1:3000, #7777) and anti-FOXO3α (1:3000, #12829) from Cell Signaling Technology; anti-Flag (1:10000) and anti-β-actin

(6) Hsa_circ_0039569 facilitates the progression of endometrial carcinoma by targeting the miR-197/high mobility group protein A1 axisBioengineeredFebruary 8, 2022Yi Zhou, Anyi Pan, Yudong Zhang, Xinchun LiSDS–PAGE and then transferred to PVDF membranes. HMGA1 primary antibody (Cell Signaling Technology, #7777) was used and incubated with PVDF membranes overnight at 4°C. Next, the membranes were incubated with

(7) Diverse heterochromatin-associated proteins repress distinct classes of genes and repetitive elementsNature cell biologyAugust 1, 2021McCarthy RL, Kaeding KE, Keller SH, Zhong Y, Xu L, Hsieh A, Hou Y, Donahue G, Becker JS, Alberto O, et al.(Active Motif 39155, Lot 31618020), anti-ERH (Millipore Sigma HPA002567), anti-HMGA1 (Cell Signaling 7777S), anti-MYBBP1A (Millipore Sigma HPA005466), anti-ZNF622 (Bethyl A304–075A), anti-CEBPz (Bethyl A303–153A),

(8) MicroRNA‑296‑5p inhibits cell proliferation by targeting HMGA1 in colorectal cancerExperimental and Therapeutic MedicineMay 24, 2021Guohui Yan, Shuidi Yan, Jiajia Wang, Shen Lei, Weimin Tian, Xin Yue, Yang Zhangstreptomycin, at 37˚C with 5% CO2. Reagents. The antibodies used in this study included: Anti‑HMGA1 (cat. no. 7777; Cell Signaling Technology, Inc.), anti‑GAPDH (cat. no. G8795; Sigma‑Aldrich; Merck KGaA) and HRP‑conjugated

(9) Circ_0035483 Functions as a Tumor Promoter in Renal Cell Carcinoma via the miR-31-5p-Mediated HMGA1 UpregulationCancer Management and ResearchJanuary 25, 2021Zheng Liu, Ronghai Wang, Guangze ZhuE-cadherin (CST, #3195, 1:1000), Vimentin (CST, #5741, 1:1000), Snail (CST, #3879, 1:1000), HMGA1 (CST, #7777, 1:1000), β-actin (CST, #4970, 1:1000). Detection of Glucose Consumption and Lactate Production Glucose

(10) Circ_0035483 Functions as a Tumor Promoter in Renal Cell Carcinoma via the miR-31-5p-Mediated HMGA1 UpregulationCancer Manag ResJanuary 25, 2021Zheng Liu, Ronghai Wang, Guangze ZhuE-cadherin (CST, #3195, 1:1000), Vimentin (CST, #5741, 1:1000), Snail (CST, #3879, 1:1000), HMGA1 (CST, #7777, 1:1000), β-actin (CST, #4970, 1:1000). Detection of Glucose Consumption and Lactate Production Glucose

(11) The Nuclear Function of IL-33 in Desensitization to DNA Damaging Agent and Change of Glioma Nuclear StructureFrontiers in cellular neuroscienceJanuary 1, 2021Chung YH, Qian Q, Huang HY, Chiu WT, Yang CS, Tzeng SF.(DYKDDDDK),Thermo Fishier Scientific Cat# MA1-91878.,1:1000 (WB) Rabbit anti HMGA1,Cell signaling Cat# 7777,1:2500 (WB) Rabbit anti HMGA1,Cell signaling Cat# 5269,1:2500 (WB) Biotinylated anti-mouse IgG,Abcam

(12) A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic ProteinsFrontiers in pediatricsJanuary 1, 2021El-Soussi S, Hanna R, Semaan H, Khater AR, Abdallah J, Abou-Kheir W, Abou-Antoun T.Cell Signaling Technology), FABP5 (rabbit mAb 39926S; Cell Signaling Technology), HMGA1 (rabbit mAb 7777S; Cell Signaling Technology), p-ERK (sc-7383; Santa Cruz Biotechnology, Dallas, TX, USA), ERK1/2 (rabbit

(13) Long Noncoding RNA SNHG22 Induces Cell Migration, Invasion, and Angiogenesis of Gastric Cancer Cells via microRNA-361-3p/HMGA1/Wnt/β-Catenin AxisCancer Management and ResearchDecember 15, 2020Xiaofeng Cui, Huaiyu Zhang, Tong Chen, Wei Yu, Kexin Shenskimmed milk, overnight membrane probing was conducted with primary antibodies against HMGA1 [1:1000, #7777, Cell Signaling Technologies (CST), Beverly, MA, USA], β-catenin (1:1000, #8480, CST), and the internal

(14) Long Noncoding RNA SNHG22 Induces Cell Migration, Invasion, and Angiogenesis of Gastric Cancer Cells via microRNA-361-3p/HMGA1/Wnt/β-Catenin AxisCancer Manag ResDecember 15, 2020Xiaofeng Cui, Huaiyu Zhang, Tong Chen, Wei Yu, Kexin Shenskimmed milk, overnight membrane probing was conducted with primary antibodies against HMGA1 [1:1000, #7777, Cell Signaling Technologies (CST), Beverly, MA, USA], β-catenin (1:1000, #8480, CST), and the internal

(15) A novel lncRNA PLK4 up-regulated by talazoparib represses hepatocellular carcinoma progression by promoting YAP-mediated cell senescenceJournal of cellular and molecular medicineMay 1, 2020Jia Y, Jin H, Gao L, Yang X, Wang F, Ding H, Chen A, Tan S, Zhang F, Shao J, et al.(10883‐1‐AP) and p21 (10355‐1‐AP) were purchased from Proteintech Group, Inc Primary antibodies against Hmga1 (7777), Ki67 (9449) and YAP (14074) were procured by Cell Signaling Technology. 2.2 Microarray assay Fresh

(16) A Novel Mechanism of 17-AAG Therapeutic Efficacy on HSP90 Inhibition in MYCN-Amplified Neuroblastoma CellsFrontiers in oncologyJanuary 1, 2020Hanna R, Abdallah J, Abou-Antoun T.Cell signaling technology), Oct4 (2840S; Cell signaling technology), FABP5 (39926S; Cell signaling technology), HMGA1 (7777S; Cell signaling technology), PHB (2426S; Cell signaling technology), p-ERK (sc-7383; Santa Cruz Biotechnology)

(17) The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivityPLOS ONEMay 8, 2019Syed Moiz Ahmed et al.antibodies (α-HMGA2 (CST 5269; 1:1000; RRID:AB_10694917, Ab41878; 1:200; RRID:AB_2279684), α-HMGA1 (CST 7777S; 1:1000; D6A4), α-Topoisomerase I (Ab109374; 1:2000; RRID:AB_10861978), α-β-Actin (Sigma A2228; 1:5000;

(18) MicroRNA‑363‑3p inhibits hepatocarcinogenesis by targeting HMGA2 and is associated with liver cancer stageMolecular Medicine ReportsNovember 29, 2018Jing Wang, Huimin Liang, Haize Ge, Xinling Guo, Dongmei Gu, Yuhua Yuantemperature. The nitrocellulose membranes were incubated with primary antibody (anti-HMGA2, 1:1,000, 7777; and anti-β-actin, 1:6,000, 4970; both Cell Signaling Technology, Inc., Danvers, MA, USA) overnight

(19) IL-24 modulates the high mobility group (HMG) A1/miR222 /AKT signaling in lung cancer cellsOncotargetSeptember 2, 2016Janani Panneerselvam, Akhil Srivastava, Ranganayaki Muralidharan, Qi Wang, Wei Zheng, Lichao Zhao, Alshine Chen, Yan D. Zhao, Anupama Munshi, Rajagopal RameshPrimary antibodies against IL-24 (1:2000; Introgen Therapeutics, Houston, TX, USA), HMGA1 (Cat. No. 7777), HMGA2 (Cat. No. 8179), phospho-AKTS473(Cat. No. 4060), total AKT (Cat. No. 9272) and PPP2R2A (Cat.

(20) MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cellsBritish Journal of CancerSeptember 1, 2016Karthik Subramanian Chandrasekaran, Anusha Sathyanarayanan, Devarajan Karunagarantransferred to a PVDF membrane (Immunoblot, Bio-Rad) using a Bio-Rad Mini PROTEAN III apparatus. Anti-HMGA1 (no. 7777S) and anti-ACTB (no. A5441) antibodies were purchased from Cell Signaling (Danvers, MA, USA) and Sigma-Aldrich

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HMGA1 (D6A4) XP ® Rabbit mAb

HMGA1 (D6A4) XP ® Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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HMGA1 (D6A4) XP ® Rabbit mAb from Cell Signaling Technology

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