c-Myb (D2R4Y) Rabbit mAb 12319S from Cell Signaling Technology

Product Specs
Itemc-Myb (D2R4Y) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12319S
Quantity100 µl
ApplicationsW, IP
ReactivityH
ClonalityMonoclonal
Targetc-Myb
HostRabbit
NCBI Full Gene NameMYB proto-oncogene, transcription factor
NCBI Gene AliasesCmyb, c-myb, c-myb_CDS, efg
Research AreaDevelopmental Biology
CloneD2R4Y
Molecular Weight80

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) MYB and HIF1α crosstalk drives hypoxia-induced transcriptional reprogramming and adaptive signaling alterations in pancreatic cancerCancer LettersOctober 28, 2025Shashi Anand, Kunwar Somesh Vikramdeo, Mohammad Aslam Khan, Seema Singh, Ajay Pratap Singhcells were incubated overnight at 4 °C with a 1:100 dilution of anti-MYB rabbit monoclonal antibody (#12319S, Cell Signaling Technology, Danvers, MA, USA), followed by washing with 1 × PBS and incubation for 60

(2) MYB/AKT3 axis is a key driver of ovarian cancer growth, aggressiveness, and chemoresistanceJournal of ovarian researchAugust 11, 2025Vikramdeo KS, Miree O, Anand S, Sharma A, Srivastava SK, Singh S, Rocconi RP, Singh AP.siRNA (cat #L-003002-00-0005) (Lafayette, CO) was used. Primary antibodies used were anti-MYB (cat #12319), AKT3 (cat #14982), pAKT (#4060), E-cadherin (cat #3195), N-Cadherin (cat #13116), anti-GSK3β (cat

(3) Reversible downregulation of HLA class I in adenoid cystic carcinomaJ Immunother CancerApril 20, 2025Annie Li, Bianca L Gonda, Elizabeth M Codd, Adam von Paternos, Dawn R Mitchell, Markus D Herrmann, Prinjali Kalyan, Samantha E Flynn, Thuc Q Dzu, Chengzhuo Gao, et al.for NFIB are most likely due to the multiple NFIB isoforms previously reported,63 anti-c-MYB (1:500, 12319, Cell Signaling), anti-B2M (1:500, MA5-36022, Invitrogen), and anti-cyclophilin B (1:5,000, 43603S,

(4) PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glandsJ Exp Clin Cancer ResJanuary 11, 2025Vasudha Mishra, Alka Singh, Michael Korzinkin, Xiangying Cheng, Claudia Wing, Viktoria Sarkisova, Ashwin L. Koppayi, Alexandra Pogorelskaya, Oksana Glushchenko, Manu Sundaresan, et al.were used: anti-SDMe-arginine (Cell Signaling Technology, 13222), anti-MYB (Cell Signaling Technology, 12319), anti-MYC (Abcam, ab32072), anti-AXL (Abcam, ab215205), anti-AKT (Cell Signaling Technology, 4691 S),

(5) Latent Epstein-Barr virus infection collaborates with Myc over-expression in normal human B cells to induce Burkitt-like Lymphomas in micePLoS pathogensApril 1, 2024Bristol JA, Nelson SE, Ohashi M, Casco A, Hayes M, Ranheim EA, Pawelski AS, Singh DR, Hodson DJ, Johannsen EC, et al.(Cell Signaling #3332), anti-JAK2 (Cell Signaling #3230), anti-LMP1 (Abcam #ab78113), anti-c-Myb (Cell Signaling #12319), anti-c-Myc (Abcam #ab32072), anti-p100/52 (Cell Signaling #3017), anti-RAG1 (Cell Signaling #3968),

(6) An enhancer variant associated with breast cancer susceptibility in Black women regulates TNFSF10 expression and antitumor immunity in triple-negative breast cancerHuman molecular geneticsJanuary 1, 2023Han YJ, Zhang J, Hardeman A, Liu M, Karginova O, Romero R, Khramtsova GF, Zheng Y, Huo D, Olopade OI.c-MYB proteins, 1–10 fmols of oligonucleotides or 100–200 ng of anti-c-MYB antibodies (Cell Signaling, #12319) in the presence of 2.5% glycerol, 5 mM MgCl2 and 0.05% NP-40 using the LightShift Chemiluminescent EMSA kit

(7) Development and Characterization of MYB-NFIB Fusion Expression in Adenoid Cystic CarcinomaCancersApril 30, 2022Humtsoe JO, Kim HS, Jones L, Cevallos J, Boileau P, Kuo F, Morris LGT, Ha P.[20]. MYBwt or MYB-NFIB fusion protein were detected with anti-MYB (N-terminus epitope) D2R4Y, cat #12319 (Cell Signaling Tech. Inc, Danvers, MA, USA); anti-MYB (N-teminus epitope) EP769Y, Ab45150 (Abcam.,

(8) Arachidonic acid-regulated calcium signaling in T cells from patients with rheumatoid arthritis promotes synovial inflammationNature communicationsFebruary 10, 2021Ye Z, Shen Y, Jin K, Qiu J, Hu B, Jadhav RR, Sheth K, Weyand CM, Goronzy JJ.recognizing p-CAMKII (Thr286, #12716), p-ERK (Thr202/Tyr204, #4377s), CAMKII (#4436), ERK (#4695), Myb (#12319), AP-2a (#3208), and IKAROS (#9034s) were from Cell Signaling. Abs to β-actin (#A5441) were obtained

(9) Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinaseNature communicationsJuly 3, 2020Wilkes MC, Siva K, Chen J, Varetti G, Youn MY, Chae H, Ek F, Olsson R, Lundbäck T, Dever DP, et al.1:1000, #3535; Cell Signaling; 1:500), phosphoThr298-NLK (orb157946; biorbyt; 1:350 dilution), c-Myb (#12319; Cell Signaling; 1;1000 dilution), Raptor (#AB26264; Abcam 1;1000 dilution), phospho-Ser863 Raptor (#PAS-64849;

(10) Overexpression of MYB in the Skin Induces Alopecia and Epidermal HyperplasiaJournal of Investigative DermatologyJune 1, 2020Yuan Hu, Zhongya Song, Jiang Chen, Carlos Caulinfor MYB on skin samples from control and K5-Myb mice at P55, using two different antibodies CST (# 12319S) and Abcam (# ab45150). (b) Myb mRNA expression detected by in situ hybridization (top panels) and immunohistochemistry

(11) CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcomaNature chemical biologyJanuary 1, 2020Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, et al.(Cell Signaling Technologies 13987, dilution 1:1000), anti-MYB antibody (Cell Signaling Technologies 12319, dilution 1:1000), anti-MEK1/2 (Cell Signaling 8727, dilution 1:1000), anti-Vimentin (Cell Signaling

(12) The Oncogenic Kaposi's Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA FamilyCell reportsDecember 3, 2019Morrison K, Manzano M, Chung K, Schipma MJ, Bartom ET, Gottwein E.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies "Myb; rabbit monoclonal, 1:500",Cell Signaling,Cat# 12319S; RRID:AB_2716637 "PDCD4; rabbit monoclonal, 1:1000",Cell Signaling,Cat# D29C6; RRID:AB_2162318 "STAT3;

(13) Immunogenic neoantigens derived from gene fusions stimulate T cell responsesNature medicineMay 1, 2019Yang W, Lee KW, Srivastava RM, Kuo F, Krishna C, Chowell D, Makarov V, Hoen D, Dalin MG, Wexler L, et al.1:1,000), PE anti-active caspase-3 (BD cat# 550821, 1:50), anti-c-Myb Clone D2R4Y (Cell Signaling cat# 12319, 1:1,000), anti-DEK Clone E1L3V (Cell Signaling cat# 13962, 1:1,000), anti-HLA-ABC Monoclonal Antibody

(14) Regulation of miR-181a expression in T cell agingNature CommunicationsDecember 1, 2018Zhongde Ye, Guangjin Li, Chulwoo Kim, Bin Hu, Rohit R. Jadhav, Cornelia M. Weyand, Jörg J. Goronzyfrom EMD Millipore (07–360), and antibodies against pERK (T202/Y204, 4377s), SIRT1 (2310s), and MYB (12319S) from Cell Signaling Technology were used at a dilution of 1 in 1000 for immunoblotting or 1 in 50 for

(15) METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m⁶A ModificationCell stem cellFebruary 1, 2018Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen C, Hu C, et al.(GE Healthcare). Antibodies used for Western blotting were as follows: METTL14 (HPA038002, Sigma-Aldrich), MYB (12319, Cell Signaling Technology), MYC (13987, Cell Signaling Technology), HA (11867423001, Roche, Basel,

(16) MicroRNA-548c-3p inhibits T98G glioma cell proliferation and migration by downregulating c-MybOncology LettersMay 1, 2017Jianyi Lu, Min Zhang, Xiao Yang, Tong Cui, Jinpo Daiovernight with primary antibodies (described below) at 4˚C. Antibodies directed against c‑Myb (1:1,000; cat. no. 12319), protein lin‑28 homolog B (Lin28b; 1:1,000; cat. no. 4196), Myc proto‑oncogene protein (Myc; 1:1,000;

(17) IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing StudyPLoS medicineDecember 1, 2016Li Y, Buijs-Gladdines JG, Canté-Barrett K, Stubbs AP, Vroegindeweij EM, Smits WK, van Marion R, Dinjens WN, Horstmann M, Kuiper RP, et al.

(18) Upregulation of miRNA-155 expression by OxLDL in dendritic cells involves JAK1/2 kinase and transcription factors YY1 and MYBInternational Journal of Molecular MedicineMay 1, 2016HUI YAN, SHUAI WANG, ZHENWEI LI, WENTING ZHAO, ZHEN WANG, ZEWEI SUN, YANYUN PAN, JIANHUA ZHUwere subsequently probed using primary antibodies: rabbit antiYY1 (1:1,000; #2185), rabbit anti-MYB (1:1,000; #12319) and rabbit anti-Janus kinase 1/2 (JAK1/2) (1:1,000; H‑103) (all from Cell Signaling Technology, Beverly,

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c-Myb (D2R4Y) Rabbit mAb

c-Myb (D2R4Y) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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c-Myb (D2R4Y) Rabbit mAb from Cell Signaling Technology

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