IL-1beta (D4T2D) Rabbit mAb 12426S from Cell Signaling Technology

Product Specs
ItemIL-1beta (D4T2D) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12426S
Quantity100 µl
ApplicationsW
ReactivityM
ClonalityMonoclonal
TargetIL1 beta mouse
HostRabbit
NCBI Full Gene Nameinterleukin 1 beta
NCBI Gene AliasesIL-1beta, Il-1b
Research AreaImmunology and Inflammation
CloneD4T2D
Molecular Weight17,31

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Protective Effects of Cyclosporin H Against Sepsis-Induced Acute Kidney Injury via Modulation of Fpr1 Signaling and Inhibiting PyroptosisRes Rep UrolMarch 7, 2026Hangwei Feng, Linqian Jiang, Cuilian WengBiological Technology Co. Ltd., A00362-4), anti-FPR1 (1:500) (Abcam, ab113531), anti-IL-1β (1:1000) (CST, 12426S), and anti-GAPDH (1:5000) (Proteintech, 10494-1-AP) as internal reference. Membranes were then incubated

(2) Infosomes as Inflammatory Mediators: Proteomic Profiling of Proteins Enriched in Inflammatory Extracellular VesiclesMolecular & Cellular ProteomicsFebruary 1, 2026Semin Lee, Minjun Kim, Seungmin Lee, Hyo-Jin Kim, Ki-Jun Ryu, Sang-Hun Kim, Hong-Yeoul Ryu, Kyunghee Lee, Kwang Dong Kim, Jiyun Yoo, et al.Life Sciences Cat. No. AG-20B-0014-C100), IL-1β (Cell Signaling Technology, Inc.; Cat. No. #12703 or #12426), cleaved IL-1β (Cell Signaling Technology, Inc.; Cat. No. #83186 or #52718), Caspase-1 (Cell Signaling Technology

(3) Thonningianin A derived from Penthorum chinense Pursh alleviates cerebral ischemia/reperfusion-mediated apoptosis and pyroptosis through the activation of PINK1/Parkin-dependent mitophagyChinese MedicineJanuary 16, 2026Qianfang Yao, Guishan Hu, Can Yin, Anguo Wu, Guangqiang Hu, Dalian Qin, Xiaogang Zhou, Betty Yuen-Kwan Law, Xi Du, Li Chen, et al.from Public Protein/Plasmid Library (PPL, Nanjing, China). Antibodies including NLRP3 (15101S), IL-1β (12426S), IL-18 (57058), Nrf2 (12721S), BAX (14796S), Bcl2 (3498S), HO-1 (70081S) were purchased from Cell Signaling Technologies

(4) Nucleotide metabolic rewiring enables NLRP3 inflammasome hyperactivation in obesityScienceJanuary 15, 2026Danhui Liu, Chuanli Zhou, Xiaochen Wang, Zhou Luo, Ruiyao Xu, Shanshan Huo, Lina Guo, Xuemei Luo, Shuhan Yang, Arielle Click, et al.(AG-20B-0042-C100, Adipogen), anti-human caspase-1 (AG-20B-0048-C100, Adipogen), anti-mouse IL-1β (12426S, Cell Signaling Technologies), anti-human IL-1β (12703S, Cell Signaling Technologies), anti- zebrafish

(5) GPR43 alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome activation via β-arrestin 2Biology DirectJanuary 10, 2026Changli Wang, Wangzheqi Zhang, Yu Guo, Yan Liao, Na Li, Yan Zhang, Lulong Bo, Jinjun Bian, Jia-feng Wang(AG-20B-0014-C100, AdipoGen, 1:2000), Anti-Caspase-1 (AG-20B-0042-C100, AdipoGen, 1:1000), Anti-IL-1β (#12426, Cell Signaling Technology, 1:1000), Anti-Cleaved-IL-1β (#63124, Cell Signaling Technology, 1:1000),

(6) Deficient chaperone-mediated autophagy in macrophages aggravates colitis and colitis-associated tumorigenesis in miceMolecules and CellsDecember 1, 2025Weichun Zhu, Zehao Chen, Yunqian Gao, Chungang Zhai, Xia Li, Ning Wang, Kang Fu, Wentao Chen, Jieqiong Peng, Dan Xu, et al.(OM267735, Omnimabs), Hif-1α (ab179483, Abcam), VEGFR2 (2479, CST), IL-1β (ab9722, Abcam), Pro-IL-1β (#12426, CST), and β-actin (#4970, CST). Rinse with TBST 3 times for 5 minutes each time, and HRP-conjugated

(7) Optimized processing of Gardenia Fruits with ginger juice: Unveiling therapeutic mechanisms for cholestatic liver injury through TLR4/NF-κB, FXR/PPAR-α, and PI3K/AKT/GSK-3βPLOS OneSeptember 16, 2025Chenzi Lyu, Xianglong Meng, Juan Wang, Haifeng Shao, Yang Wang, Yong-Ki Park, Shuosheng Zhang, Hyo Won JungDilution1:1000), TNF-α (Cat No. 11948S, Dilution1:1000), IL-6 (Cat No. 12912S, Dilution1:1000), IL-1β (Cat No. 12426S, Dilution1:1000), FXR (Cat No. 72105S, Dilution1:1000), AKT (Cat No.9272S, Dilution1:1000), p-AKT (Cat

(8) Gut microbiota and its metabolites promote painful diabetic peripheral neuropathy complicated with cognitive dysfunction in miceFrontiers in Cellular and Infection MicrobiologySeptember 2, 2025Junpeng Yang, Xin Lv, Ya Xu, Fenglian Huang, Xueli Yang, Xiaoyang Shi, Lingyun Zhao, Chenghong Liang, Danyu Wang, Yuanyuan Fang, et al.(18934 - 1-AP) was provided by Proteintech (Wuhan, China).The primary antibodies of NLRP3 (#15101), IL - 1β (#12426), caspase-1 (#24232), GAPDH (#97166) and tubulin (#2148) used in western blot were provided by Cell Signaling Technology

(9) Neutrophil Extracellular Traps Promote AIM2-Dependent Microglial Pyroptosis Following StrokeAging DisJune 2, 2025Hanze Chen, Linhui Ni, Jinhua Zhang, Xu Zheng, Yigang Chen, Xing Jin, Beibei Hu, Xinxin Xu, Qiwen Tang, Shuang Li, et al.AdipoGen), rabbit anti-GSDMD (1:1 000, ab219800; Abcam), rabbit anti-interleukin (IL)-1β (1:1 000, 12426S; Cell Signaling Technology), rabbit anti-IL-18 (1:1 000, 57058S; Cell Signaling Technology), rabbit

(10) MK5 Regulates Microglial Activation and Neuroinflammation in Experimental Stroke ModelsCNS Neurosci TherApril 16, 2025Xingzhi Wang, Wenqi Mao, Li Du, Fei Wang, Ye Pang, Yangdanyu Li, Guangci Xu, Guiyun Cui(1:1000, rabbit; 89872, CST, USA), CD206 (1:1000, rabbit; 24595, CST, USA), IL‐1β (1:1000, rabbit; 12426, CST, USA), TNF‐α (1:1000, rabbit; 3707, CST, USA), NF‐κB (1:1000, rabbit; 8242, CST, USA), phospho‐NF‐κB

(11) Neuroprotective effects and mechanisms of the YiQiWenYangSanHan formula on Parkinson's disease miceIBRO Neurosci RepApril 1, 2025Jinling Liu, Dong Di, Suping Sun, Yan Sun, Shihan Zhou, Jing Liu, Zizhen Qin, Xinyu Yang, Xiao Wang, Zheng Xu, et al.(#58844, 1:1000), NLRP3 (#15101, 1:1000), Caspase-1 (#24232, 1:1000), ASC (#67824, 1:1000), IL-1β (#12426, 1:1000), α-syn (#51510, 1:1000), PAR (#83732, 1:1000), PARP (#9542, 1:1000) were obtained from Cell Signaling Technology

(12) Exogenous L-Serine Alleviates Pasteurella multocida-Induced Inflammation by Reprogramming the Transcription and Metabolism of MacrophagesVet SciMarch 7, 2025Fang He, Zhengchun Lang, Yanlan Huang, Yangyang Qiu, Pan Xiong, Nengzhang Li, Guangfu Zhao, Yuanyi PengNLRC4 (bs-20016R, 1:1000, Bioss, Beijing, China), AIM2 (ab180665, 1:1000, Abcam, Cambridge, UK), IL-1β (12426s, 1:1000, CST, MA, USA), and Caspase-1 (ab179515, 1:1000, Abcam, Cambridge, UK). Murine primary peritoneal

(13) A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasomeElifeFebruary 25, 2025Yan Qian, Qiannv Liu, Xiangyun Cheng, Chunlei Wang, Chun Kong, Mengqian Li, Chao Ren, Dong Jiang, Shuo Wang, Pengyan Xiaresponse. Materials and methods Antibodies and reagents Antibodies against NLRP3 (15101), IL-1β (12703, 12426), cleaved IL-1β (83186, 63124), GSDMD (93709), caspase-1 (3866, 24232, 2225), and ASC (13833, 67824)

(14) Oral Microbially-Induced Small Extracellular Vesicles Cross the Blood-Brain BarrierInternational journal of molecular sciencesApril 20, 2024Elashiry M, Carroll A, Yuan J, Liu Y, Hamrick M, Cutler CW, Wang Q, Elsayed R.MA, USA), anti-human IL-1B (#12703) (Cell Signaling Technology, Danvers, MA, USA), anti-mouse IL1B (#12426) (Cell Signaling Technology, Danvers, MA, USA), anti-Grp94 (#2104) (Cell Signaling Technology, Danvers,

(15) Hope for vascular cognitive impairment: Ac-YVAD-cmk as a novel treatment against white matter rarefactionPLOS ONEApril 17, 2024Yun-An Lim, Li Si Tan, Wei Thye Lee, Wei Liang Sim, Yang Lv, Maki Takakuni, Satoshi Saito, Masafumi Ihara, Thiruma Valavan Arumugam, Christopher Chen, et al.Signalling Technology, #67314), cleaved caspase 11 (Abcam, ab22684), IL-1β (Cell Signalling Technology, #12426S), VCAM-1 (Santa Cruz, sc-8304), zonula occludens-1 (ZO-1) (Santa Cruz Biotechnology, #sc-33725), occludin

(16) Hepatitis B virus-mediated sodium influx contributes to hepatic inflammation via synergism with intrahepatic danger signalsiScienceJanuary 19, 2024Wang J, Liu Q, Zhou Y, Cao C, Chen P, Meng G, Zhang J, Xin X, Huang G, Wu Y.Techonology,2225 anti-caspase-1,AdipoGen,AG-20B-0042RRID:AB_2490248 anti-P2X7,Abcam,ab109246RRID:AB_10858498 anti-NLRP3,Santa,sc134306RRID:AB_2152550 anti-NLRP3,Sigma-Aldrich,HPA012878RRID:AB_1846752 anti-cleaved IL-1β,Cell signaling Techonology,83186 anti-IL-1β,Cell signaling Techonology,12426 anti- IL-1β,R&D,AF-401-NARRID:AB_416684 anti-IL-18,Abcam,ab243091RRID:AB_2861283 anti-cleaved GSDMD

(17) Proximal Tubular Lats2 Ablation Exacerbates Ischemia/Reperfusion Injury (IRI)-Induced Renal Maladaptive Repair through the Upregulation of P53International Journal of Molecular SciencesOctober 17, 2023Chi Zhang, Zhihuang Zheng, Kexin Xu, Guozhe Cheng, Huijuan Wu, Jun Liu(Cat# 99940S, CST), monoclonal rabbit anti-IL-18 (Cat# 57058S, CST), monoclonal rabbit anti-IL-1β (Cat# 12426, CST), polyclonal rabbit anti-phospho-MDM2 (Ser186) (Cat# bs-5471R, Bioss, Woburn, MA, USA), monoclonal

(18) NLRP3 inflammasome inhibition of OP9 cells enhance therapy for inflammatory bowel diseaseHeliyonJuly 1, 2023Chen Y, Meng W, Ren G, An N, Zhang J, Liu Z, Wu X, Yin W, Hu X, Liu Z, et al.Anti-mouse antibodies like NLRP3 (#AG-20B-0014, Adipogen), Caspase1-p20 (#AG-20B-0042, Adipogen), IL-1β (#12426, Cell Signaling Technology), GSDMDC1 (#sc-393656, Santa Cruz Biotechnology), alpha Tubulin (#66031-1-1

(19) Induction of Innate Inflammatory Pathways in the Corneal Epithelium in the Desiccating Stress Dry Eye ModelInvestigative ophthalmology & visual scienceApril 3, 2023Yu Z, Yazdanpanah G, Alam J, de Paiva CS, Pflugfelder S.Thermo Fisher Scientific), IL-18BP (cat. no. A6445, 1:1000; ABclonal Technology, Woburn, MA, USA), or IL-1β (cat. no. 12426, 1:1000; Cell Signaling Technology, Danvers, MA, USA) overnight. After secondary antibody incubation,

(20) Development of a method to identify persistent and blanchable redness by skin blotting in miceInternational wound journalApril 1, 2023Nakai A, Minematsu T, Nitta S, Hsu WJ, Tobe H, Sanada H.antibodies (1:200; ab1316, Abcam); anti‐HSP90α (1:100; ab13492, Abcam) and anti‐IL‐1β antibodies (1:1000; 12426S, Cell Signalling Technology, Danvers, MA); anti‐VEGF‐C (1:500; 22 601‐1‐AP, Proteintech) and anti‐IL‐6

Be the First to Write a Review!

IL-1beta (D4T2D) Rabbit mAb (Mouse Specific)

IL-1beta (D4T2D) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (71)

Reviews

IL-1beta (D4T2D) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map