Brn2/POU3F2 (D2C1L) Rabbit mAb 12137S from Cell Signaling Technology

Product Specs
ItemBrn2/POU3F2 (D2C1L) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12137S
Quantity100 µl
ApplicationsW, IP, IF-F, ChIP, ChIP-seq, C&R, C&T
ReactivityH, M, R
ClonalityMonoclonal
TargetPOU3F2/Brn2
HostRabbit
NCBI Full Gene NamePOU class 3 homeobox 2
NCBI Gene AliasesBRN2, N-Oct3, OCT7, OTF-7, OTF7, POUF3, brn-2, oct-7
Research AreaNeuroscience
CloneD2C1L
Molecular Weight55

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Cell Signaling Technology

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Phone: 978-867-2388
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Targeting Wnt/β-Catenin and circadian regulator restores PRC2/EZH2 controlled chromatin bivalency and suppresses cell state diversityJournal of Clinical InvestigationMay 1, 2026Yatian Yang, Xiong Zhang, Varadha Balaji Venkadakrishnan, Hongye Zou, Xingling Zheng, Shiyao Guo, Christopher Z. Chen, Alexander D. Borowsky, Eva Corey, Ronald M. Evans, et al.against β-catenin (BD Biosciences, catalog 610153), BRN2/POU3F2 (Cell Signaling Technology, catalog 12137), KMT2B (Cell Signaling Technology, catalog 63735S) — all diluted at 1:1,000 — and Rev-Erbα (Cell Signaling

(2) Uncoupling neocortical neuron fate and migration via a Let-7-RBX2 axisProc Natl Acad Sci U S AApril 28, 2026Steven C. Decker, Keiko Hino, Anna La Torre, Sergi Simóconfocal microscope. Primary antibodies used: Cux1 (Proteintech, 11733-1-AP, 1:200), Brn2 (Cell Signaling, 12137, 1:200), Ctip2 (Abcam,ab18465, 1:200), Foxp2 (EMD Millipore, MABE415, 1:50). Western Blotting. For western blotting

(3) SOX2 phosphorylation during mitosis limits genomic damageGenes & DevelopmentFebruary 2, 2026Charles A.C. Williams, Dounia Djeghloul, Nicolas Veland, Alhafidz Hamdan, Maria Kalantzaki, Erika Lo, Robert Illingworth, Alex Von Kriegsheim, Amanda G. Fisher, Abdenour Soufi, et al.Santa Cruz Biotechnology sc55584), HP1a (1:50; Millipore 05-689), BRN2 (1:1000; Cell Signaling Technology 12137), GAPDH (1:10,000; Invitrogen AM4300), histone H3 (1:1000; Abcam ab9080), pS10 histone H3 (1:1000; Cell Signaling Technology

(4) Cloud-Connected Pluripotent Stem Cell Platform Enhances Scientific Identity in Underrepresented StudentsbioRxivJanuary 25, 2026Samira Vera-Choqqueccota, Drew Ehrlich, Vladimir Luna-Gomez, Sebastian Hernandez, Jesus Gonzalez-Ferrer, Hunter E. Schweiger, Kateryna Voitiuk, Yohei Rosen, Kivilcim Doganyigit, Isabel Cline, et al.Abcam #ab5392), mouse anti-Tuj1 (1:1000, BioLegend #801202), rabbit anti-Brn2 (1:500, Cell Signaling #12137), mouse anti-Tle4 (1:200, Santa Cruz Biotechnology #sc-365406). Following three PBS washes, secondary

(5) The hegemonic EWSR1::ETS oncoprotein overrules core regulatory circuitry principles in Ewing sarcomanpj Precision OncologyDecember 25, 2025Sandrine Grossetete, Sakina Zaidi, Martin F. Orth, Sarah Morice, Karine Laud, Caroline Louis-Brennetot, Anna Sole Ferre, Virginie Perrin, Florencia Cidre-Aranaz, Virginie Raynal, et al.incubated overnight at 4 °C with rabbit anti-POU3F1 (Abcam, ab259952), rabbit anti-POU3F2 (Cell signaling, 12137), and rabbit anti-vinculin (Abcam, ab129002). Membranes were then incubated for 1 h at room temperature

(6) Syngap1 and the development of murine neocortical progenitor cellsNat CommunDecember 11, 2025Soraia Barão, Yijun Xu, Ingie Hong, Ulrich Müller, Richard L. Huganirrabbit polyclonal, 11733-1-AP Proteintech, current lot: 00050220); anti-BRN2 (1:1000, rabbit monoclonal, 12137 Cell Signaling, clone D2C1L); anti-Ki67 (1:500, rabbit polyclonal, ab15580 Abcam, current lot: GR3285096-1

(7) POU3F2 regulates canonical Wnt signalling via SOX13 and ADNP to expand the neural progenitor populationBrainDecember 4, 2025Courtney R Benoit, Lilia B Sattler, Aimee J Aylward, Olivia Pembridge, Bella Kim, Christina R Muratore, Meichen Liao, Amy He, Nancy Ashour, Seeley B Fancher, et al.incubated with primary antibody diluted in blocking buffer overnight at 4°C: POU3F2 (CST, Cat. No. 12137S, 1:100), Nestin (Novus Biologicals, Cat. No. MAB1259, 1:500), PAX6 (Biolegend, Cat. No. 901301, 1:400),

(8) Enhanced Notch dependent gliogenesis and delayed physiological maturation underlie neurodevelopmental defects in Lowe syndromeEMBO Molecular MedicineNovember 11, 2025Yojet Sharma, Priyanka Bhatia, Gagana Rangappa, Sankhanil Saha, Padinjat Raghu(1:200),Sigma-Aldrich,A2052 Rat anti-CTIP2 (1:800),Abcam,ab18465 Rabbit anti-BRN2 (1:200),Cell Signalling Technologies,12137 Rabbit anti-TBR1 (1:200),Abcam,ab31940 "Chicken anti-GFAP (1:1000, IF; 1:2000 WB)",Novus Biologicals,NBP1-05198 Rabbit

(9) Optineurin deficiency disrupts phosphorylated tau proteostasis and clusterin expression in human neuronsActa Neuropathologica CommunicationsSeptember 2, 2025Zachary M. Augur, Garrett M. Fogo, Mason R. Arbery, Andrew M. Stern, Courtney R. Benoit, Yi-Chen Hsieh, Tracy L. Young-Pearse9632S Rabbit anti-OPTN,Proteintech,Cat# 10837-1-AP Rabbit anti-BRN2,Cell Signaling Technologies,Cat# 12137S Mouse anti-OPA1,Thermo Fisher Scientific,Cat# 612606 Mouse anti-TAU,Thermo Fisher Scientific,Cat#

(10) Identification of MUC1-C Dependence in Drug-Resistant Advanced Prostate Cancer Uncovers a Target for Antibody-Drug Conjugate TherapyJCI InsightJuly 22, 2025Keisuke Shigeta, Tatsuaki Daimon, Hiroshi Hongo, Sheng-Yu Ku, Hiroki Ozawa, Naoki Haratake, Atsushi Fushimi, Ayako Nakashoji, Atrayee Bhattacharya, Shinkichi Takamori, et al.1:1,000 dilution; Cell Signaling Technology [CST]), anti-MYCN (9405, 1:1,000 dilution; CST), anti-BRN2 (12137, 1:1,000 dilution; CST), anti-ASCL1 (GTX129189, 1:1,000 dilution; GeneTex), anti-GLUT1 (115730, 1:1,000

(11) PlexinD1 is a driver and a therapeutic target in advanced prostate cancerEMBO Molecular MedicineJanuary 2, 2025Jing Wei, Jing Wang, Wen Guan, Jingjing Li, Tianjie Pu, Eva Corey, Tzu-Ping Lin, Allen C Gao, Boyang Jason Wu,Cell Signaling Technology,9649 GAPDH (WB: 1/1000),Santa Cruz Biotechnology,sc-47724 BRN2 (WB: 1/1000),Cell Signaling Technology,12137 Ki-67 (IHC: 1/400),Cell Signaling Technology,9027 Human IgG Fc (WB: 1/1000; co-IP: 1/50),Sigma-Aldrich,I2136 FLAG

(12) Syngap1 and the development of murine neocortical progenitor cellsbioRxivDecember 22, 2024Soraia Barao, Ingie Hong, Ulrich Mueller, Richard L. Huganiranti-CUX1 (1:1000, rabbit polyclonal, 11733–1-AP Proteintech); anti-BRN2 (1:1000, rabbit monoclonal, 12137 Cell Signaling); anti-Ki67 (1:500, rabbit polyclonal, ab15580 Abcam or 1:500, rat monoclonal, 14–5698-82

(13) Mouse models of Slc35a2 brain mosaicism reveal mechanisms of mild malformations of cortical development with oligodendroglial hyperplasia in epilepsyEpilepsiaDecember 1, 2024Hyojung Yoon, Amanda Ringland, James J. Anderson, Sahibjot Sran, Soad Elziny, Cindy Huynh, Noriyuki Shinagawa, Samantha Badertscher, Rachel R. Corrigan, Lauren Mashburn‐Warren, et al.sections were incubated overnight with the following antibodies: BRN2 (Cell Signaling Technology, Cat# 12137), OLIG2 (Abcam, Cat# ab109186), CTIP2 (Abcam, Cat# ab18465), or SATB2 (Abcam, Cat# AB92446). The next

(14) Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelinationGliaDecember 1, 2024Wilson ER, Nunes GD, Shen S, Moore S, Gawron J, Maxwell J, Syed U, Hurley E, Lanka M, Qu J, et al.Meijer POU3F1/OCT6,Rabbit,1:2000 (WB)1:500 (IHC),Gift from Dies Meijer POU3F2/BRN2,Rabbit,1:1000 (WB),Cell Signaling (12137) JUN,Rabbit,1:750 (WB)1:200 (IHC),Cell Signaling (9165) SOX10,Rabbit,1:1000 (WB)1:500 (IHC),Cell Signaling

(15) A spatial–temporal map of glutamatergic neurogenesis in the murine embryonic cerebellar nuclei uncovers a high degree of cellular heterogeneityJournal of AnatomyOctober 1, 2024Filippo Casoni, Laura Croci, Francesca Marroni, Giulia Demenego, Chiara Marullo, Ottavio Cremona, Franca Codazzi, G. Giacomo Consalezwith manufacturer's instructions. 2.5 Antibodies BRN2, rabbit, 1:500, Cell Signaling, catalog number 12137, RRID:AB_2797827, requires antigen unmasking; LMX1a, rabbit, 1:3000, Millipore, catalog number AB10533,

(16) Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansionNature communicationsSeptember 14, 2024Barão S, Xu Y, Llongueras JP, Vistein R, Goff L, Nielsen KJ, Bae BI, Smith RS, Walsh CA, Stein-O'Brien G, et al.anti-BRN2 (1:1000, rabbit polyclonal, PA5-30124 Thermo Fisher Scientific or 1:1000, rabbit monoclonal, 12137 Cell Signaling); anti-BRN1 (1:1000, rabbit polyclonal, sc-6028-R Santa Cruz Biotechnology); anti-CRE

(17) Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusionsNeuronSeptember 4, 2024Isabel Lam, Alain Ndayisaba, Amanda J. Lewis, YuHong Fu, Giselle T. Sagredo, Anastasia Kuzkina, Ludovica Zaccagnini, Meral Celikag, Jackson Sandoe, Ricardo L. Sanz, et al.III, clone TUJ1",Stem Cell Technologies,Cat. # 60052 "Anti-Brn2, clone D2C1L",Cell Signaling,Cat. # 12137; RRID:AB_2797827 Anti-Ctip2,Abcam,Cat. # ab18465; RRID:AB_2064130 Anti-Cux1 (Anti-Protein CASP; 2A10),Abcam,Cat.

(18) A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neuronsNPJ Parkinson's diseaseMay 21, 2024White AJ, Clark KA, Alexander KD, Ramalingam N, Young-Pearse TL, Dettmer U, Selkoe DJ, Ho GPH.160003), N-cadherin (rabbit, Abcam ab76011), PMCA1 (rabbit, Abcam ab190355), POU3F2/Brn2 (rabbit, CST mab#12137), SNAP-25 (rabbit, Abcam ab5666), vGlut2 (mouse, Abcam ab79157 clone 8G9.2). Induced neurons (iNs) The

(19) Transcription factor activating enhancer-binding protein 2ε (AP2ε) modulates phenotypic plasticity and progression of malignant melanomaCell Death & DiseaseMay 21, 2024Sebastian Staebler, Ulrike Rottensteiner-Brandl, Zubeir El Ahmad, Melanie Kappelmann-Fenzl, Andreas Arkudas, Annika Kengelbach-Weigand, Anja-Katrin Bosserhoff, Sonja K. SchmidtCat# ab233928, RRID:AB_2943147) and anti-BRN2 primary antibody (1:200, Cell Signaling Technology Cat# 12137, RRID:AB_2797827), was used, respectively. BRN2 and MITF staining was described quantitatively using

(20) LSD1 Regulates Neurogenesis in Human Neural Stem Cells Through the Repression of Human-Enriched Extracellular Matrix and Cell Adhesion GenesStem CellsFebruary 8, 2024Channakkar AS, D'Souza L, Kumar A, Kalia K, Prabhu S, Phalnikar K, Reddy PC, Muralidharan B.Santa Cruz-sc-365406" CTIP2,"Rat, Abcam-ab18465" SATB2,"Mouse, Abcam-ab51502" BRN2,"Rabbit, CST-12137S" GFAP,"Mouse, Sigma-G3893" S100B,"Chicken, Synaptic systems-287 006"

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Brn2/POU3F2 (D2C1L) Rabbit mAb

Brn2/POU3F2 (D2C1L) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Brn2/POU3F2 (D2C1L) Rabbit mAb from Cell Signaling Technology

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