ATP2A1/SERCA1 (D54G12) Rabbit mAb 12293S from Cell Signaling Technology

Product Specs
ItemATP2A1/SERCA1 (D54G12) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12293S
ApplicationsWestern Blot (WB)
Research AreaCa, cAMP and Lipid Signaling
IsotypeIgG
CloneD54G12
Molecular Weight100
ReactivityHu, Ms
NCBI Gene AliasesATP2A, SERCA1
NCBI Full Gene NameATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
HostRabbit
TargetATP2A1
ClonalityMonoclonal
Quantity100 µl

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Skeletal Muscle PGC-1α Remodels Mitochondrial Phospholipidome but Does Not Alter Energy Efficiency for ATP SynthesisJ Cachexia Sarcopenia MuscleOctober 9, 2025Takuya Karasawa, Ran Hee Choi, Cesar A. Meza, Shinya Watanabe, J. Alan Maschek, Linda S. Nikolova, James E. Cox, Katsuhiko Funai12957‐1‐AP, 1:2000), sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) 1 (Cell Signaling Technology, 12293, 1:1000), SERCA2 (Abcam, ab3625, 1:1000), myosin heavy chain (MHC) type IIa (Developmental Studies Hybridoma Bank [DSHB

(2) Altered Relaxation and Mitochondria‐Endoplasmic Reticulum Contacts Precede Major (Mal)Adaptations in Aging Skeletal Muscle and Are Prevented by ExerciseAging CellSeptember 1, 2025Ryan J. Allen, Ana Kronemberger, Qian Shi, R. Marshall Pope, Elizabeth Cuadra‐Muñoz, Wangkuk Son, Long‐Sheng Song, Ethan J. Anderson, Renata O. Pereira, Vitor A. Liraat 95°C for 5 min. The primary antibodies used for this study were: ATP2A1/SERCA1 (Cell Signaling, 12293), VDAC1 (Cell Signaling, 4661), Alpha‐tubulin (Abcam, ab7291), PERK (Cell Signaling, 3192), Citrate

(3) Modulating intracellular calcium dynamics with alkaloids: A novel strategy against oxidative neurodegenerationToxicol Res (Camb)July 27, 2025Serap Niğdelioğlu Dolanbay,Thermo Fisher Scientific CALM1,ab61001,1/500,17,Abcam CaMK2A,"sc-13,141",1/100,50,Santa Cruz PMCA (ATP2B1),Ab190355,1/1000,135,Abcam SERCA (ATP2A1),#12293,1/1000,100,Cell Signaling Technologies RyR1,"26,968-1-AP",1/500,565,Proteintech IP3R (ITPR1),ab264281,1/2000,313,Abcam "Goat

(4) The GIP receptor activates futile calcium cycling in white adipose tissue to increase energy expenditure and drive weight loss in miceCell MetabolismJanuary 7, 2025Xinxin Yu, Shiuhwei Chen, Jan-Bernd Funcke, Leon G. Straub, Valentina Pirro, Margo P. Emont, Brian A. Droz, Kyla AI. Collins, Chanmin Joung, Mackenzie J. Pearson, et al.sarcolipin (1:1000, ABT-13; Millipore), anti-rabbit monoclonal SERCA1 and SERCA2 antibodies (1:1000, #12293 and #9580; Cell Signaling), anti-rabbit SERCA1a and SERCA2a antibodies (1:1000 and 1:7000, respectively;

(5) Integrative Proteogenomics for Differential Expression and Splicing Variation in a DM1 Mouse ModelMolecular & Cellular ProteomicsJanuary 1, 2024Elizaveta M. Solovyeva, Stephan Utzinger, Alexandra Vissières, Joanna Mitchelmore, Erik Ahrné, Erwin Hermes, Tania Poetsch, Marie Ronco, Michael Bidinosti, Claudia Merkl, et al.Primary antibodies were obtained from Cell Signaling—Rb anti-BIN1 mAB (#51844) and Rb anti-SERCA1 mAb (#12293). Biotinylated conjugate anti-Rb was used for secondary antibody (Jess Anti Rabbit detection module

(6) Skeletal muscle releases extracellular vesicles with distinct protein and microRNA signatures that function in the muscle microenvironmentPNAS NexusSeptember 1, 2022Watanabe S, Sudo Y, Makino T, Kimura S, Tomita K, Noguchi M, Sakurai H, Shimizu M, Takahashi Y, Sato R, et al.Abcam; anti-CD81 (#10037), anti-Alix (#92880), anti-desmin (#5332), anti-Tom20 (#42406), anti-ATP2A1 (#12293), anti-GAPDH (#5174), HRP-linked anti-mouse IgG (#7076), and HRP-linked anti-rabbit IgG (#7074) antibodies

(7) Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrityMolecular MetabolismNovember 1, 2021Astrid L. Basse et al.CYPD (#110324, Abcam), BAX (#2772, Cell Signaling), p-CREB (Ser133, #9198, Cell Signaling), SERCA1 (#12293, Cell Signaling), and Poly (ADP-ribose) (#ALX-804-220, ENZO Lifescience). 2.3.5 Hematoxylin and eosin

(8) Exercise, but Not Metformin Prevents Loss of Muscle Function Due to Doxorubicin in Mice Using an In Situ MethodInternational Journal of Molecular SciencesAugust 25, 2021Amy D. Mackay, Erik D. Marchant, Makensie Louw, David M. Thomson, Chad R. Hancock(Thr 172) (1:4000; #2535 Cell-Signaling Technology Inc., Danvers, MA, USA), and ATP2A1/SERCA1 (1:500; #12293 Cell-Signaling Technology, Inc., Danvers, MA, USA). Membranes were washed in TBST 4 times for 5 min,

(9) Pharmacological activation of SERCA ameliorates dystrophic phenotypes in dystrophin-deficient mdx miceHuman Molecular GeneticsMay 31, 2021Ken'ichiro Nogami et al.CA, USA). Data were analyzed using Image Lab 6.0 (Bio-Rad). Antibodies Antibodies against SERCA1 (#12293) and SERCA2a (#4388) were purchased from Cell Signaling Technologies (Beverly, MA, USA). Anti-caspase-3

(10) Cytochalasin H isolated from mangrove-derived endophytic fungus inhibits epithelial-mesenchymal transition and cancer stemness via YAP/TAZ signaling pathway in non-small cell lung cancer cellsJournal of CancerJanuary 1, 2021Zihan Xiu, Jiao Liu, Xin Wu, Xiangyong Li, Sanzhong Li, Xiaofeng Wu, Xiaohua Lv, Hua Ye, Xudong Tangdilution; cat. no. 2750), Nanog (1:1000 dilution; cat. no. 4903), and TEAD (1:1000 dilution; cat. no. 12293) primary antibodies were purchased from Cell Signaling Technology (Danvers, MA, USA). Mouse anti-human

(11) Restoration of SERCA ATPase prevents oxidative stress-related muscle atrophy and weaknessRedox BiologyJanuary 1, 2019Rizwan Qaisar, Shylesh Bhaskaran, Rojina Ranjit, Kavithalakshmi Sataranatarajan, Pavithra Premkumar, Kendra Huseman, Holly Van RemmenFrederick, MD, USA). Primary antibodies used include rabbit anti-SERCA1 (Cell Signaling technology; #12293, Danvers, MA, USA), rabbit anti-SERCA2 (Cell Signaling technology; #4388, Danvers, MA, USA) and rabbit

(12) Calcium dysregulation, functional calpainopathy, and endoplasmic reticulum stress in sporadic inclusion body myositisActa neuropathologica communicationsMarch 22, 2017Amici DR, Pinal-Fernandez I, Mázala DA, Lloyd TE, Corse AM, Christopher-Stine L, Mammen AL, Chin ER.subsequent analyses. Antibodies and concentrations used were: anti-SERCA1 1:1000 (Cell Signaling Technology #12293s), anti-SERCA2 1:1000 (Thermo Fischer #9580s), anti-MCU 1:2000 (Cell Signaling Technology #14997), anti-CSQ

(13) Transient Receptor Potential Channel 1 Deficiency Impairs Host Defense and Proinflammatory Responses to Bacterial Infection by Regulating Protein Kinase Cα SignalingMolecular and cellular biologyAugust 1, 2015Zhou X, Ye Y, Sun Y, Li X, Wang W, Privratsky B, Tan S, Zhou Z, Huang C, Wei YQ, et al.number 34673), phospho-JNK (catalog number 9258), STIM1 (catalog number 4916), SECRA (catalog number 12293), and JNK (catalog number 9251) were purchased from Cell Signaling Technology (Cambridge, MA). Mouse

(14) Diaphragm Fatigue in SMNΔ7 Mice and Its Molecular Determinants: An Underestimated IssueInternational journal of molecular sciencesJanuary 1, 0001Cadile F, Recchia D, Ansaldo M, Rossi P, Rastelli G, Boncompagni S, Brocca L, Pellegrino MA, Canepari M.,Cell Signaling,#5114 PINK1,Rabbit,1:1000,Invitrogen,#PA1-16604 PARKIN,Mouse,1:2000,Invitrogen,#39-0900 Tubulin,Mouse,1:2000,Sigma,T6199 OXPHOS,Mouse,1:1000,Abcam,Ab110413 SERCA1,Rabbit,1:1000,Cell Signaling,#12293 SERCA2,Rabbit,1:1000,Cell Signaling,#9580 Antibodies used for Western Blot Analysis.

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ATP2A1/SERCA1 (D54G12) Rabbit mAb

ATP2A1/SERCA1 (D54G12) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (14)

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ATP2A1/SERCA1 (D54G12) Rabbit mAb from Cell Signaling Technology

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