Somatostatin R2/SSTR2 Antibody MAB4224 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemSomatostatin R2/SSTR2 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $479.00Supplier Page View Company Product Page
Catalog NumberMAB4224
ApplicationsAssay Development,Flow Cytometry,Immunohistochemistry,Western Blot,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready
IsotypeIgG2a
Clone402038
Quantity100 ug (also 25 ug)
HostMouse
TargetSomatostatin R2/SSTR2
ReactivityHuman,Primate
Conjugate/TagUnconjugated
NCBI Full Gene Namesomatostatin receptor 2
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenNS0 mouse myeloma cell line transfected with Somatostatin R2/SSTR2, Met1-Ile369, Accession # P30874
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesSST2

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human Somatostatin R2/SSTR2. Stains SSTR2 transfectants but not irrelevant transfectants.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) PET imaging of 52Mn labeled DOTATATE and DOTAJR11Sci RepJanuary 18, 2025James M. Omweri, Hailey A. Houson, Shannon E. Lynch, Volkan Tekin, Anna G. Sorace, Suzanne E. Lapifluorophore-conjugated antibodies for 30 min in the dark at 4 ºC. Antibodies utilized were 1 µg SSTR2 (Novus, #MAB4224) conjugated with Cy5.5 (LumiProbe, 7321-10rxn), and Near-IR Dead Cell Stain Kit (ThermoFisher, L34975).

(2) Immune Cell Molecular Pharmacodynamics of Lanreotide in Relation to Treatment Response in Patients with Gastroenteropancreatic Neuroendocrine TumorsCancers (Basel)September 7, 2024Sabah Alaklabi, Orla Maguire, Harsha Pattnaik, Yali Zhang, Jacky Chow, Jianmin Wang, Hans Minderman, Renuka Iyerexpression,SSTR expression Rb anti-SSTR1,N/A,UMB7,Abcam,ab137083 Ms anti-SSTR2,N/A,402038,Biotechne,MAB4224 Rb anti-SSTR3,N/A,UMB5,Abcam,ab137026 Rb anti-SSTR4,N/A,Polyclonal,Abcam,ab28578 Ms anti-SSTR5,N/A,394401,Biotechne,MAB4448 Dky

(3) The Wnt pathway protein Dvl1 targets somatostatin receptor 2 for lysosome-dependent degradationThe Journal of biological chemistryMay 1, 2023Carr HS, Zuo Y, Frost JA.Anti-6xHis tag was from Thermo Fisher Scientific (14-6657-82). Anti-Sstr2 mouse monoclonal antibody (#MAB4224) was from R&D Systems. Mouse monoclonal anti-pan-Dvl antibody (sc-166303) was from Santa Cruz Biotechnology.

(4) Combination of [(177)Lu]Lu-DOTA-TATE Targeted Radionuclide Therapy and Photothermal Therapy as a Promising Approach for Cancer Treatment: In Vivo Studies in a Human Xenograft Mouse ModelPharmaceuticsJune 16, 2022Simón M, Jørgensen JT, Khare HA, Christensen C, Nielsen CH, Kjaer A.FC block to decrease unspecific staining before staining with mouse anti-human SSTR2 antibody (1:50, MAB4224, R&D Systems, Minneapolis, USA) and viability dye (1:400, eFluor™ 780, Thermo Fisher Scientific). This

(5) Development of anti-somatostatin receptors CAR T cells for treatment of neuroendocrine tumorsJournal for immunotherapy of cancerJune 1, 2022Mandriani B, Pellè E, Mannavola F, Palazzo A, Marsano RM, Ingravallo G, Cazzato G, Ramello MC, Porta C, Strosberg J, et al.in paraformaldehyde and incubated overnight at 4°C with a mouse mAb against SSTR2 (R&D Systems, cat#MAB4224) or a rabbit polyclonal Ab targeting SSTR5 (Novus Biologicals, cat#NB100-74540). Cells were then incubated

(6) Evaluation of Ac-Lys(0)(IRDye800CW)Tyr(3)-octreotate as a novel tracer for SSTR(2)-targeted molecular fluorescence guided surgery in meningiomaJournal of neuro-oncologyJune 1, 2021Dijkstra BM, de Jong M, Stroet MCM, Andreae F, Dulfer SE, Everts M, Kruijff S, Nonnekens J, den Dunnen WFA, Kruyt FAE, et al.CH-157MN cells in vitro was determined by analyzing sections of Cellient blocks stained for SSTR2 (MAB4224, R&D systems). Separate consecutive FFPE sections of tissue obtained from animal studies were used for

(7) Primate cell fusion disentangles gene regulatory divergence in neurodevelopmentNatureApril 1, 2021Agoglia RM, Sun D, Birey F, Yoon SJ, Miura Y, Sabatini K, Pașca SP, Fraser HB.R&D Systems, MAB6166), anti-SOX9 (goat, 1:300, R&D Systems, AF3075), anti-SSTR2 (mouse, 1:100, R&D systems, MAB4224), anti-MAP2 (guinea pig, 1:200, Synaptic Systems, 188 004), and anti-TUBB3 (rabbit, 1:200, Cell Signaling TECHNOLOGY

(8) (177)Lu-DOTA-EB-TATE, a Radiolabeled Analogue of Somatostatin Receptor Type 2, for the Imaging and Treatment of Thyroid CancerClinical cancer research : an official journal of the American Association for Cancer ResearchMarch 1, 2021Thakur S, Daley B, Millo C, Cochran C, Jacobson O, Lu H, Wang Z, Kiesewetter D, Chen X, Vasko V, et al.membranes were incubated overnight at 4oC with a primary antibody against SSTR2 (1:400, R&D systems, MAB4224), acetylated histone 3 (1:500, Millipore, 06–599) or acetylated histone 4 (1:500, Millipore, 06–598),

(9) Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatmentSurgeryJanuary 1, 2020Guenter R, Aweda T, Carmona Matos DM, Jang S, Whitt J, Cheng YQ, Liu XM, Chen H, Lapi SE, Jaskula-Sztul R.replicate were stained for 30 minutes at 37°C with 1μg of an anti-SSTR2 antibody (Novus Biologicals Cat#MAB4224) labeled with Cy5.5 fluorophore (Lumiprobe). Cells were then resuspended in flow buffer (0.5% BSA in

(10) Pulmonary Carcinoid Surface Receptor Modulation Using Histone Deacetylase InhibitorsCancersJune 3, 2019Guenter RE, Aweda T, Carmona Matos DM, Whitt J, Chang AW, Cheng EY, Liu XM, Chen H, Lapi SE, Jaskula-Sztul R.TDP-A for 48 h. After treatment, cells were stained for 1 h at 37 °C with an anti-SSTR2 antibody (Cat#MAB4224, Novus Biologicals, Centennial, CO, USA) labeled with Cy5.5 fluorophore (Lumiprobe, Hunt Valley, MD,

(11) Development and application of a high-content virion display human GPCR arrayNature communicationsApril 30, 2019Syu GD, Wang SC, Ma G, Liu S, Pearce D, Prakash A, Henson B, Weng LC, Ghosh D, Ramos P, et al.human GPCRs were purchased from R&D system (MAB197, MAB330, MAB331, MAB190, MAB6594, MAB4139, MAB099, MAB4224, MAB8396, MAB42273, MAB150, MAB179, MAB8276, MAB2016, MAB8561, MAB145, MAB1567, MAB699, and MAB9305)

(12) SSTR-2 as a potential tumour-specific marker for fluorescence-guided meningioma surgeryActa neurochirurgicaAugust 1, 2018Dijkstra BM, Motekallemi A, den Dunnen WFA, Jeltema JR, van Dam GM, Kruyt FAE, Groen RJM.a blocking step with 1% H2O2 in PBS for 10 min. Cells were then incubated with anti-SSTR-2 (1:100; MAB4224, R&D systems) for 1 h, followed by incubation of the corresponding secondary and tertiary antibodies

(13) Targeting Somatostatin Receptors By Functionalized Mesoporous Silica Nanoparticles - Are We Striking Home?NanotheranosticsJanuary 1, 2018Paramonov VM, Desai D, Kettiger H, Mamaeva V, Rosenholm JM, Sahlgren C, Rivero-Müller A.analysis. Antibodies Primary Abs recognizing intracellular epitopes that were used on permeabilized cells: anti-SSTR2 (MAB4224; R&D systems; mouse monoclonal Ab (mAb); 1:250), anti-SSTR3 (UMB-5; Abcam; rabbit mAb; 1:800), anti-SSTR5

(14) Identification of critical residues involved in ligand binding and G protein signaling in human somatostatin receptor subtype 2EndocrinologyJune 1, 2012Parry JJ, Chen R, Andrews R, Lears KA, Rogers BE.

(15) Clinical significance of protein expression of cyclooxygenase-2 and somatostatin receptors in gastroenteropancreatic neuroendocrine tumorsCancer research and treatment : official journal of Korean Cancer AssociationSeptember 1, 2011Kim HS, Lee HS, Kim WH.mouse monoclonal, DAKO), SSTR1 (1 : 100, ab2366, rabbit polyclonal, Abcam, Cambridge, UK), SSTR2 (1 : 100, MAB4224, mouse monoclonal, R&D systems, Minneapolis, MN), and SSTR5 (1 : 100, PAB0299, rabbit polyclonal, Abnova,

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Somatostatin R2/SSTR2 Antibody

Somatostatin R2/SSTR2 Antibody

Somatostatin R2/SSTR2 Antibody

Somatostatin R2/SSTR2 Antibody

Somatostatin R2/SSTR2 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (15)

Reviews

Somatostatin R2/SSTR2 Antibody from R&D Systems, a Bio-Techne Brand

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