PerCP/Cyanine5.5 anti-mouse CD117 (c-kit) 105823 from BioLegend

Product Specs
ItemPerCP/Cyanine5.5 anti-mouse CD117 (c-kit)
CompanyBioLegend
Price $118.00Supplier Page View Company Product Page
Catalog Number105823
Quantity25 µg
Conjugate/TagPerCP/Cyanine5.5
ApplicationsFC - Quality tested
Concentration0.2mg/ml
FormatPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
HostRat
Clone2B8
ReactivityMouse
IsotypeRat IgG2b, kappa
Antibody TypePrimary
ImmunogenMouse bone marrow mast cells
TargetCD117
NCBI Gene AliasesBs, CD117, Fdc, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Ssm, Tr-kit, W, c-KIT
NCBI Full Gene NameKIT proto-oncogene receptor tyrosine kinase
ClonalityMonoclonal

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BioLegend

8999 BioLegend Way

San Diego, California 92121

United States

Phone: 1-877-246-5343 Toll-Free, USA & Canada
1-858-768-5800 International
Fax: 1-877-455-9587

Company Profile

Website: biolegend.com

(1) Mechanometabolism instructs hematopoietic stem cell specificationJournal of Experimental MedicineMarch 2, 2026Paulina D. Horton, Alina Syed, Michelle Winkler, Abishek B. Vaidya, Michael Rariden, Neha Arora, Yong Zhou, Michihiro Kobayashi, Momoko Yoshimoto, Hyun Jung Lee, et al.included EPCR/CD201 (EPCR-APC, 1:50 or 1:100, 17–2012-82, eBiosciences), cKit (cKit-PerCP-Cy5.5, 1:100, 105823, Biolegend; or cKit-AF488, 1:50, 105816, Biolegend; or cKit-PE, 1:100, 553355, BD), VE-Cadherin (VEC-BV421,

(2) BRD4 and MYB inhibition overcomes venetoclax resistance in EVI1-rearranged acute myeloid leukemiaSci RepOctober 23, 2025Weijia Zang, Yui Koike, Koutarou Nishimura, Atsushi Tanaka, Hiromi Yamazaki, Takaya Yamasaki, Hiromi Ito, Yifan Zhang, Yumi Aoyama, Wataru Saika, et al.101228; 1:300); c-Kit-FITC (2B8; eBioscience; 553354; 1:300); anti-mouse CD45-PerCPCy5.5 (2B8; Biolegend; 105824; 1:1000) and anti-human CD45-BV510 (HI30; Biolegend; 304036; 1:100). The following antibodies were used

(3) Selective requirement of glycosphingolipid synthesis for natural killer and cytotoxic T cellsCellJune 26, 2025Tasha A. Morrison, Jaelyn Vigee, Kevin A. Tovar, Taylor A. Talley, Adriana M. Mujal, Mari Kono, Rachael Philips, Hiroyuki Nagashima, Stephen R. Brooks, Hannah Dada, et al.,Thermo Fisher Scientific,Cat# 13-0051-82; RRID:AB_466339 Anti-mouse CD117 (c-Kit) (clone 2B8),BioLegend,Cat# 105824; RRID:AB_2131597 Anti-mouse Sca-1 (clone D7),BioLegend,Cat# 108143; RRID:AB_2629684 Anti-mouse α4β7

(4) Dominant immune tolerance in the intestinal tract imposed by RelB-dependent migratory dendritic cells regulates protective type 2 immunityNature communicationsOctober 23, 2024Geiselhöringer AL, Kolland D, Patt AJ, Hammann L, Köhler A, Kreft L, Wichmann N, Hils M, Ruedl C, Riemann M, et al.CD103-PE (clone 2E7, catalog number 121406, dilution 1:100), CD117-PerCP/Cy5.5 (clone 2B8, catalog number 105824, dilution 1:100), CD11c-BV786 (clone N418, catalog number 117335, dilution 1:200), CD172α-PE-Cy7 (clone

(5) Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblastsMolecular CellOctober 17, 2024Xiaohui Lin, Dipika Gupta, Alina Vaitsiankova, Seema Khattri Bhandari, Kay Sze Karina Leung, Demis Menolfi, Brian J. Lee, Helen R. Russell, Gershik Gershik, Xiaoyu Huang, et al.103006), PE anti-mouse CD71 (BioLegend, 113807), PerCP/Cyanine5.5 anti-mouse CD117 (c-Kit) (BioLegend, 105823), PE/Cyanine7 anti-mouse/human CD45R/B220 (BioLegend, 103222), APC anti-mouse Ly6G/Ly6C (Thermo Fisher Scientific

(6) A Myb enhancer-guided analysis of basophil and mast cell differentiationNature communicationsNovember 18, 2022Matsumura T, Totani H, Gunji Y, Fukuda M, Yokomori R, Deng J, Rethnam M, Yang C, Tan TK, Karasawa T, et al.(A2F10) (Biolegend, 135305/135313, eBioscience, 17-1351-82), CD117 ( = c-kit) (2B8) (Biolegend, 105811/105823/105826/105827, BD, 558163), CD135 (A2F10) (Biolegend, 135305, eBioscience, 17-1351-82), CD150 (TC15-12F12.2)

(7) Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic TransformationCancer discoveryOctober 5, 2022Chen S, Vedula RS, Cuevas-Navarro A, Lu B, Hogg SJ, Wang E, Benbarche S, Knorr K, Kim WJ, Stanley RF, et al.1:200), anti–Ter119-APC-Cy7 (Ter119, BioLegend, 116223, 1:200), anti–c-Kit-PerCP-Cy5.5 (2B8, BioLegend, 105824, 1:100), anti–c-Kit-BV605 (ACK2, BioLegend, 135120, 1:100), anti–Sca-1-PE-Cy7 (D7, BioLegend, 108102,

(8) Centrosome function is critical during terminal erythroid differentiationThe EMBO journalJuly 18, 2022Tátrai P, Gergely F.CD48‐biotin (1:400, 103409, BioLegend), CD150‐PE (1:200, 115903, BioLegend), cKit‐PerCEP‐Cy5.5 (1:200, 105823, BioLegend), Sca1‐PE‐Cy7 (1:200, 25‐5981‐81, eBioscience), CD71‐PE (1:200, 553267, BD), TER119‐APC (1:200,

(9) Presenilin 1 phosphorylation regulates amyloid-β degradation by microgliaMolecular psychiatryOctober 1, 2021Ledo JH, Liebmann T, Zhang R, Chang JC, Azevedo EP, Wong E, Silva HM, Troyanskaya OG, Bustos V, Greengard P.Biolegend (anti-CD115 (Csfr1), 135510; anti-F4/80, 123131; anti-Cx3Cr1, 149016; anti-CD117 (c-kit), 105824; anti-Ly6c, 128033), Invitrogen (Anti-CD11b, 47-0112-82; anti-CD45, 56-0451-82) or BD-Pharmingen (anti-CD16/CD32

(10) Minor intron retention drives clonal hematopoietic disorders and diverse cancer predispositionNature geneticsMay 1, 2021Inoue D, Polaski JT, Taylor J, Castel P, Chen S, Kobayashi S, Hogg SJ, Hayashi Y, Pineda JMB, El Marabti E, et al.BioLegend; 116223: 1:200); cKit-APC (2B8; BioLegend; 105812; 1:100); cKit-PerCPCy5.5 (2B8; BioLegend; 105824; 1:100); cKit-Bv605 (ACK2; BioLegend; 135120; 1:100); Sca1-PECy7 (D7; BioLegend; 108102; 1:100); CD45.1-FITC

(11) An Autocrine Circuit of IL-33 in Keratinocytes Is Involved in the Progression of PsoriasisThe Journal of investigative dermatologyMarch 1, 2021Zeng F, Chen H, Chen L, Mao J, Cai S, Xiao Y, Li J, Shi J, Li B, Xu Y, et al.

(12) Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesisOncogeneNovember 1, 2020Karra L, Romero-Moya D, Ksionda O, Krush M, Gu Z, Mues M, Depeille P, Mullighan C, Roose JP.,Tonbo Bioscience,60-0452-U100,1:200 B220-PerCP-Cy5.5,Tonbo Bioscience,65-0452-U100,1:100 c-Kit-PerCP-Cy5.5,BioLegend,105823-BL,1:200 CD3-APC,Tonbo Bioscience,20-0032-U100,1:200 CD3-PE-Cy7,BD Bioscience,560591,1:100 CD4-PE-Cy7,eBioscience,25-0042-82,1:200 CD4-PerCP-Cy5.5,Tonbo Bioscience

(13) Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue HomeostasisCell reportsAugust 11, 2020De Koninck M, Lapi E, Badía-Careaga C, Cossío I, Giménez-Llorente D, Rodríguez-Corsino M, Andrada E, Hidalgo A, Manzanares M, Real FX, et al.

(14) Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during developmentPloS oneJanuary 1, 2020Ledo JH, Zhang R, Mesin L, Mourão-Sá D, Azevedo EP, Troyanskaya OG, Bustos V, Greengard P.Biolegend (anti-CD115 (Csfr1), 135510; anti-F4/80, 123131; anti-Cx3Cr1, 149016; anti-CD117 (c-kit), 105824; antiLy6c, 128033), Invitrogen (Anti-CD11b, 47-0112-82; anti-CD45, 56-0451-82) or BD-Pharmingen (anti-CD16/CD32

(15) Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesisNatureOctober 1, 2019Yoshimi A, Lin KT, Wiseman DH, Rahman MA, Pastore A, Wang B, Lee SC, Micol JB, Zhang XJ, de Botton S, et al.(BioLegend; 116223: 1:200); cKit-APC (2B8; BioLegend; 105812; 1:200); cKit-PerCPCy5.5 (2B8; BioLegend; 105824; 1:100); cKit-Bv605 (ACK2; BioLegend; 135120; 1:200); Sca1-PECy7 (D7; BioLegend; 108102; 1:200); CD16/CD32

(16) Polychromic Reporter Mice Reveal Unappreciated Innate Lymphoid Cell Progenitor Heterogeneity and Elusive ILC3 Progenitors in Bone MarrowImmunityJuly 16, 2019Walker JA, Clark PA, Crisp A, Barlow JL, Szeto A, Ferreira ACF, Rana BMJ, Jolin HE, Rodriguez-Rodriguez N, Sivasubramaniam M, et al.CD62L (MEL-14),Biolegend,Cat#104438; RRID: AB_2563058 Anti-mouse CD117 (c-Kit) (2B8),Biolegend,Cat#105824; RRID: AB_2131597 Anti-mouse IL-5 (TRFK5),Biolegend,Cat#504306; RRID: AB_315330 Anti-mouse CCR6 (CD196)

(17) Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic ItchImmunityMay 21, 2019Meixiong J, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, Oetjen LK, Wang F, Kim BS, Dong X.Brilliant Violet 510 anti-mouse/human CD11b,BioLegend,Cat#101245; RRID: AB_2561390 PerCP/Cy5.5 anti-mouse CD117,BioLegend,Cat#105823; RRID: AB_2131598 FITC anti-mouse CD45,BioLegend,Cat#103108; RRID: AB_312973 "IgE Monoclonal (23G3),

(18) Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesisNature communicationsNovember 22, 2017Schuler F, Weiss JG, Lindner SE, Lohmüller M, Herzog S, Spiegl SF, Menke P, Geley S, Labi V, Villunger A.

(19) The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell DevelopmentImmunityMay 16, 2017Miyazaki M, Miyazaki K, Chen K, Jin Y, Turner J, Moore AJ, Saito R, Yoshida K, Ogawa S, Rodewald HR, et al.D,FAB2145P Anti-mouse LPAM-1,BD,562376 Anti-mouse PLZF,Sant Cruz Biotechnology,Sc-28319 Anti-mouse CD117,Biolegend,105824 Anti-mouse Rorgt,eBioscience,12-6988 Anti-mouse CD117,eBioscience,47-1172 Anti-mouse CCR6,Biolegend,129818 Anti-mouse

(20) Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammationAging (Albany NY)November 21, 2016Irina Tsoy Nizamutdinova, Giuseppina F. Dusio, Olga Yu. Gasheva, Hunter Skoog, Richard Tobin, Chander Peddaboina, Cynthia J. Meininger, David C. Zawieja, M. Karen Newell-Rogers, Anatoliy A. Gashevfollowing antibodies: rat PerCP/Cy5.5-conjugated anti-c-kit (BioLegend, San Diego, CA, USA, catalog #105823, dilution 1:100) and mouse anti-mast cell tryptase (Abcam, Cambridge, MA, USA, catalog # ab2378, dilution

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PerCP/Cyanine5.5 anti-mouse CD117 (c-kit) from BioLegend

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PerCP/Cyanine5.5 anti-mouse CD117 (c-kit) from BioLegend

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