Synaptophysin1 antibody 101 002 from Synaptic Systems GmbH

Product Specs
ItemSynaptophysin1 antibody
CompanySynaptic Systems GmbH
Price $390.00Supplier Page View Company Product Page
Catalog Number101 002
ApplicationsWB, IP, ICC, IHC, IHC-P, ELISA
Quantity200 µl
Reactivityhuman, rat, mouse, hamster, cow, chicken, frog, zebrafish
Formatlyophilized
Hostrabbit
TargetSynaptophysin1
Clonalitypolyclonal
ImmunogenSynthetic peptide corresponding to AA 301 to 313 from human Synaptophysin1
Antibody TypePrimary antibody

Questions and Answers

What applications has the Synaptophysin1 antibody been used for in research studies?

The Synaptophysin1 antibody has been shown to work in various applications including Western Blotting, ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, and Electron Microscopy, as evidenced by its use in multiple scientific publications.

Can this antibody be used to study synaptic vesicle dynamics in neuronal cultures?

Yes, the Synaptophysin1 antibody has been utilized in studies examining synaptic vesicle dynamics, such as in the research by Harper et al. (2020), where it was used to investigate the expression and trafficking of synaptotagmin-1 in the context of epilepsy-associated mutations.

Is the Synaptophysin1 antibody effective for immunohistochemical staining in animal models?

The antibody has been effectively used for immunohistochemical staining in various animal models, including mouse and rat tissues, as demonstrated in studies like those by Jin et al. (2010) and Vinsant et al. (2013), where it was employed to visualize synaptic structures.

What species does the Synaptophysin1 antibody react with?

The Synaptophysin1 antibody shows reactivity with multiple species, including human, mouse, rat, bovine, chicken, hamster, zebrafish, and Xenopus, making it versatile for comparative studies across different model organisms.

Synaptic Systems GmbH

Rudolf-Wissell-Str. 28

Goettingen 37079

Germany

Phone: +49-551-50556-0
+49-551-50556-384

Company Profile

Website: http://www.sysy.com/

(1) Inflamed vessel–anchored release of H 2 across the blood-brain barrier for ischemic stroke neuroprotectionScience AdvancesFebruary 27, 2026Yuanman Yu, Mingjian Fan, Gaoyi Wu, Yongcheng Li, Chao Xia, Wenjiang Ding, Guanglin Li, Qianjun He, Wei Tang, Changsheng Liuevaluated through immunostaining of MAP2 (Sigma-Aldrich, M9942, 1:500 dilution) and SYP (Synaptic Systems, 101002, 1:500 dilution). Behavioral assessment The beam-walking test was conducted in accordance with established

(2) Functional synapses between neurons and small cell lung cancerNatureOctober 1, 2025Sakthivelu V, Schmitt A, Odenthal F, Ndoci K, Touet M, Shaib AH, Chihab A, Wani GA, Nieper P, Hartmann GG, et al.AB5895), rat anti-SP (1:200; Biogenesis, 8450-0505), guinea pig anti-SYP (1:4,000; Synaptic Systems, 101002) and rabbit anti-VGluT1 (1:250; Synaptic Systems, 135303). The following secondary antibodies were used

(3) Early-life hearing loss induces persistent cognitive deficits: evidence from human data and a mouse model with environmental interventionFrontiers in Aging NeuroscienceSeptember 25, 2025Xuehua Zhou, Huiqian Yu, Yiru Wang, Kaizheng Chen, Xia Shen(1:10000; Synaptic Systems, Göttingen, Germany; 111,002); Synaptophysin 1 (SYN1, 1:10000; Synaptic Systems; 101,002); Tau5 (1:500; Invitrogen, Waltham, MA, United States; AHB0042); Phosphorylated tau (P-Tau, Ser396,

(4) Protocol for SUM-PAINT spatial proteomic imaging generating neuronal architecture maps in rat hippocampal neuronsSTAR protocolsMarch 21, 2025Unterauer EM, Schentarra EM, Jevdokimenko K, Boushehri SS, Marr C, Opazo F, Fornasiero EF, Jungmann R.RRID:AB_2619811 Rabbit polyclonal anti-Synaptophysin (final dilution: 1:150),Synaptic Systems,Cat#101 002; RRID:AB_887905 Rabbit polyclonal anti-Spinophilin (final dilution: 1:150),Synaptic Systems,Cat#399003;

(5) Vesicular Glutamate Transporter 3 Is Involved in Glutamatergic Signalling in PodocytesInt J Mol SciMarch 11, 2025Naoko Nishii, Tomoko Kawai, Hiroki Yasuoka, Tadashi Abe, Nanami Tatsumi, Yuika Harada, Takaaki Miyaji, Shunai Li, Moemi Tsukano, Masami Watanabe, et al.anti-synaptobrevin 2 (anti-VAMP2) antibodies (cat# 104202), rabbit polyclonal anti-synaptophysin 1 antibodies (cat# 101002), and rabbit polyclonal anti-vesicular glutamate transporter 1 (anti-VGLUT1) antibodies (cat#135303)

(6) Amyloid-β can activate JNK signalling via WNT5A-ROR2 to reduce synapse formation in Alzheimer's diseaseJ Cell SciFebruary 1, 2025Kevin Fang, Ehsan Pishva, Thomas Piers, Steffen Scholpp2024), anti-GluA1 (Synaptic Systems, 1:250, 182 011), anti-synaptophysin 1 (Synaptic Systems, 1:250, 101 002), anti-β3-tubulin (Synaptic Systems, 1:500, 302 304) and anti-MAP2 (Merck, 1:500, MAB3418) antibodies.

(7) Light-Modulated Circadian Synaptic Plasticity in the Somatosensory Cortex: Link to Locomotor ActivityInternational Journal of Molecular SciencesNovember 29, 2024Małgorzata Jasińska, Ewa Jasek-Gajda, Marek Ziaja, Jan A. Litwin, Grzegorz J. Lis, Elżbieta Pyzaagainst presynaptic proteins: synaptophysin 1 (1:2000; Synaptic Systems GmbH, Goettingen, Germany, #101 002), Piccolo (1:1000; Synaptic Systems GmbH, Goettingen, Germany, #142 002) or neurexin 1/2/3 (1:500; Synaptic Systems GmbH

(8) Genetically modified E. Coli secreting melanin (E.melanin) activates the astrocytic PSAP-GPR37L1 pathway and mitigates the pathogenesis of Parkinson's diseaseJournal of nanobiotechnologyNovember 10, 2024Kong W, Liu Y, Ai P, Bi Y, Wei C, Guo X, Cai Z, Gao G, Hu P, Zheng J, et al.

(9) A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contactsJournal of Cell BiologyNovember 4, 2024Ben Johnson, Maria Iuliano, TuKiet T. Lam, Thomas Biederer, Pietro V. De Camillipermeabilized with 0.5% CHAPS in DPBS and blocked before being labeled with either rabbit anti-synaptophysin (101 002; Synaptic Systems) or mouse anti-tau (4019S; Cell Signaling) primary antibodies and either donkey anti-rabbit

(10) Knockout of Dectin-1 does not modify disease onset or progression in a MATR3 S85C knock-in mouse model of ALSHeliyonSeptember 30, 2024Justin You, Katarina Maksimovic, Mark N. Metri, Anneka Schoeppe, Karin Chen, Jooyun Lee, Jhune Rizsan Santos, Mohieldin M.M. Youssef, Michael W. Salter, Jeehye Parkfollowing primary antibodies were used: synaptophysin antibody (rabbit polyclonal, Synaptic Systems 101,002, 1:200), synapsin I antibody (rabbit polyclonal, ab64581, 1:200), and neurofilament H antibody (chicken

(11) Absence of ATG9A and synaptophysin demixing on Rab5 mutation-induced giant endosomesMolecular brainSeptember 2, 2024Choi J, Wu Y, Park D.mRFP-Rab5 [15]. Antibodies The following primary and secondary antibodies were used: anti-synaptophysin (101 002, Synaptic Systems GmbH, Goettingen, Germany), anti-HA (MMS-101R, BioLegend, San Diego, CA, USA), Alexa Fluor 594 anti-rabbit IgG

(12) Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies: Interference by cholinesterase inhibitorsBrain research bulletinJune 15, 2024Schwab K, Lauer D, Magbagbeolu M, Theuring F, Gasiorowska A, Zadrozny M, Harrington CR, Wischik CM, Niewiadomska G, Riedel G.

(13) Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neuronsProceedings of the National Academy of Sciences of the United States of AmericaApril 23, 2024Mohd Rafiq N, Fujise K, Rosenfeld MS, Xu P, De Camilli P.

(14) Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridgesProceedings of the National Academy of SciencesApril 9, 2024Swetha K. Godavarthi, Masaki Hiramoto, Yuri Ignatyev, Jacqueline B. Levin, Hui-quan Li, Marta Pratelli, Jennifer Borchardt, Cynthia Czajkowski, Laura N. Borodinsky, Lora Sweeney, et al.from Peter Scheiffele), pan-Neuroligin (1:200, Invitrogen, PA5-77523), SYN (1:200, Synaptic Systems, 101002), laminin (1:200, MilliporeSigma, L9393), Lrp4 (1:500, extracellular domain, generous gift from Stephan

(15) The CB(1) receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfallsEMBO molecular medicineApril 1, 2024Costas-Insua C, Hermoso-López A, Moreno E, Montero-Fernández C, Álvaro-Blázquez A, Maroto IB, Sánchez-Ruiz A, Diez-Alarcia R, Blázquez C, Morales P, et al.

(16) Spatial proteomics in neurons at single-protein resolutionCellMarch 28, 2024Unterauer EM, Shetab Boushehri S, Jevdokimenko K, Masullo LA, Ganji M, Sograte-Idrissi S, Kowalewski R, Strauss S, Reinhardt SCM, Perovic A, et al.

(17) Postweaning Development Influences Endogenous VPAC(1) Modulation of LTP Induced by Theta-Burst Stimulation: A Link to Maturation of the Hippocampal GABAergic SystemBiomoleculesMarch 20, 2024Gil M, Caulino-Rocha A, Bento M, Rodrigues NC, Silva-Cruz A, Ribeiro JA, Cunha-Reis D.Tech. (Danvers, MA, USA), AB_561221), rabbit polyclonal anti-synaptophysin (1:7500, Synaptic Systems #101002, RRID:AB_887905), rabbit polyclonal anti-VGAT (1:2500, Synaptic Systems #131002, RRID: AB_887871), rabbit

(18) Impaired Response to Mismatch Novelty in the Li2+-Pilocarpine Rat Model of TLE: Correlation with Hippocampal Monoaminergic InputsBiomedicinesMarch 12, 2024Carlos Nascimento, Vasco Guerreiro-Pinto, Seweryn Pawlak, Ana Caulino-Rocha, Laia Amat-Garcia, Diana Cunha-ReisCell Signalling Technology Cat#4207; RRID: AB_1264223), rabbit anti-synaptophysin (1:7500, Synaptic Systems #101002, RRID:AB_887905), and either mouse monoclonal anti-β-actin (1:5000, Proteintech #60008-1-Ig, RRID: AB_2289225)

(19) Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasisMolecular CellFebruary 15, 2024Xiaojian Shi, Marisa DeCiucis, Kariona A. Grabinska, Jean Kanyo, Adam Liu, Tukiet T. Lam, Hongying Shen(Proteintech, 15132–1-AP, 1:1000); Anti-GLRX5 (Sigma, HPA042465, 1:500); Anti-Synaptophysin 1 (Synaptic Systems,101002, 1:1000); Anti-IRP2 (Cell Signaling Technology, 37135S, 1:500); Anti-SLC25A37(Mitoferrin1) (Proteintech,

(20) Suggestion of creatine as a new neurotransmitter by approaches ranging from chemical analysis and biochemistry to electrophysiologyeLifeDecember 21, 2023Bian X, Zhu J, Jia X, Liang W, Yu S, Li Z, Zhang W, Rao Y.

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Synaptophysin1 antibody

Synaptophysin1 antibody

Synaptophysin1 antibody

Synaptophysin1 antibody

Synaptophysin1 antibody

Synaptophysin1 antibody from Synaptic Systems GmbH

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Questions and Answers

Synaptic Systems GmbH

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Synaptophysin1 antibody from Synaptic Systems GmbH

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