VMaT2 antibody 138 302 from Synaptic Systems GmbH

Product Specs
ItemVMaT2 antibody
CompanySynaptic Systems GmbH
Price $360.00Supplier Page View Company Product Page
Catalog Number138 302
NCBI Gene AliasesMNAT, VMAT-2, VMAT2
Conjugate/TagUnconjugated
TargetVMaT2
ApplicationsWB, ICC, IHC
Reactivityrat
Hostrabbit
Formatlyophilized
Quantity200 µl
Clonalitypolyclonal
ImmunogenSynthetic peptide corresponding to AA 496 to 515 from rat VMaT2
NCBI Full Gene Namesolute carrier family 18 member A2
Antibody TypePrimary antibody

Questions and Answers

Can this antibody be used for immunohistochemistry in rat brain tissues?

Yes, the VMaT2 antibody has been shown to work in immunohistochemistry applications, as evidenced by its use in studies involving rat brain tissues, where it was utilized to label specific neuronal populations.

What is the specificity of the VMaT2 antibody in terms of its target?

The VMaT2 antibody targets the vesicular monoamine transporter 2, encoded by the SLC18A2 gene, and has been cited in multiple studies focusing on its role in monoaminergic systems, particularly in the context of dopamine and serotonin transport.

How has the VMaT2 antibody been utilized in research related to neurotoxicity?

The antibody has been employed in studies examining the effects of lead exposure on the monoaminergic system, where it was used to assess changes in VMAT2 expression in the auditory brainstem of mice, indicating its relevance in neurotoxicological research.

What dilution is recommended for using the VMaT2 antibody in Western blotting?

The recommended dilution for the VMaT2 antibody in Western blotting is 1:1000, as indicated in various studies that have successfully utilized this antibody to detect VMAT2 protein levels in brain tissue preparations.

Synaptic Systems GmbH

Rudolf-Wissell-Str. 28

Goettingen 37079

Germany

Phone: +49-551-50556-0
+49-551-50556-384

Company Profile

Website: http://www.sysy.com/

(1) The gut-brain vagal axis governs mesolimbic dopamine dynamics and reward eventsScience AdvancesJanuary 30, 2026Oriane Onimus, Faustine Arrivet, Tinaïg Le Borgne, Sylvie Perez, Julien Castel, Anthony Ansoult, Benoit Bertrand, Nejmeh Mashhour, Camille de Almeida, Linh-Chi Bui, et al.Tyrosine Hydroxylase (1:1000; Rabbit, Millipore, #AB152), anti-VMAT2 (1:1000; Rabbit, Synaptic Systems, #138302), anti–β-actin (1:5000; Mouse, Sigma-Aldrich, #A1978). Detection was based on horseradish peroxidase–coupled

(2) Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeysJournal of neuropathology and experimental neurologyNovember 10, 2025He Z, Liu Z, Xu W, Zhu B, Zhang R, Wang W, Zheng X.

(3) On-Site Formation of Functional Dopaminergic Presynaptic Terminals on Neuroligin-2-Modified Gold-Coated MicrospheresACS applied materials & interfacesJanuary 24, 2024Cho W, Jung M, Yoon SH, Jeon J, Oh MA, Kim JY, Park M, Kang CM, Chung TD.

(4) Oxidative stress induced by sustained supraphysiological intrastriatal GDNF delivery is prevented by dose regulationMolecular therapy. Methods & clinical developmentDecember 14, 2023Azevedo MD, Prince N, Humbert-Claude M, Mesa-Infante V, Jeanneret C, Golzne V, De Matos K, Jamot BB, Magara F, Gonzalez-Hernandez T, et al.(Vector Laboratories). Primary antibodies were: rabbit anti-VMAT2 (1:500, Synaptic Systems, cat. no. 138,302), and mouse anti-8-oxo-dG (1:300, Travigen, cat. no. 4353-mc-050). Secondary antibodies were: Alexa

(5) Generation of self-organized autonomic ganglion organoids from fibroblastsiScienceMarch 17, 2023Liu S, Xiang K, Yuan F, Xiang M.anti-Gad65,BD Biosciences,"Cat# 559931, RRID:AB_397380" Rabbit polyclonal anti- Vmat2,Synaptic Systems,"Cat# 138 302, RRID:AB_887888" Rabbit polyclonal anti-VAChT,Synaptic Systems,"Cat# 139 103, RRID:AB_887864" Goat

(6) Deficiency of Perry syndrome-associated p150(Glued) in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalitiesNPJ Parkinson's diseaseMarch 7, 2023Yu J, Yang X, Zheng J, Sgobio C, Sun L, Cai H.transporter (DAT, Millipore, #MAB369, 1:500), vesicular monoamine transporter 2 (VMAT2, Synaptic Systems, #138302, 1:1000), glial fibrillary acidic protein (GFAP, Abcam, #ab7260, 1:1000), TAR DNA-binding protein 43

(7) Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2eLifeNovember 9, 2020Kreutzberger AJB, Kiessling V, Doyle CA, Schenk N, Upchurch CM, Elmer-Dixon M, Ward AE, Preobraschenski J, Hussein SS, Tomaka W, et al.(mouse monoclonal cat. 131 011), VATPase (rabbit polyclonal cat. 109 002), VMAT2 (rabbit polyclonal cat. 138 302), VGLUT1 (mouse monoclonal cat. 135 011), CAPS2 (rabbit polyclonal cat. 262 103), synaptobrevin-2/VAMP2

(8) Effects of sleep disruption on stress, nigrostriatal markers, and behavior in a chronic/progressive MPTP male mouse model of parkinsonismJournal of neuroscience researchDecember 1, 2019Xu M, Bohlen JK, Moore C, Nipper MA, Finn DA, Jones CE, Lim MM, Meshul CK.transporter (DAT; ProteinTech, Rabbit, 1:1000, #22524–1-AP), VMAT2 (Synaptic Systems, Rabbit, 1:1000, #138302, AB_887888) and β-actin (Sigma, Mouse, 1:6500, #A5441, AB-476744). The secondary antibodies used were

(9) Conversion of Astrocytes and Fibroblasts into Functional Noradrenergic NeuronsCell reportsJuly 16, 2019Li S, Shi Y, Yao X, Wang X, Shen L, Rao Z, Yuan J, Liu Y, Zhou Z, Zhang Z, et al.

(10) Characterization of Dmrt3-Derived Neurons Suggest a Role within Locomotor CircuitsThe Journal of neuroscience : the official journal of the Society for NeuroscienceMarch 6, 2019Perry S, Larhammar M, Vieillard J, Nagaraja C, Hilscher MM, Tafreshiha A, Rofo F, Caixeta FV, Kullander K.Japan), polyclonal guinea pig anti-Vglut2 (1:10000; AB2251, Millipore), polyclonal rabbit anti-Vmat2 (1:500; 138302, Synaptic Systems), anti-dsRed (1:400; 632498, BioNordika), polyclonal rabbit anti-Slc10a4 (1:800; HPA028835,

(11) Refinement of a neuronal differentiation protocol predominantly yields human iPS cell-derived dopaminergic neurons for the investigation of neurodegenerative pathomechanisms in vitroJournal of Cellular BiotechnologyNovember 13, 2017Yasmina Martí, Elina Nürnberg, Sandra Horschitz, Mathias Hafner, Patrick Schloss, Andreas Meyer-Lindenberg, Thorsten LauSystems (302 304) Synaptic Systems (173 111) Merck Millipore (AB152) ATS Bio (AB-N17) Synaptic Systems (138 302) Synaptic Systems (198 003) Synaptic Systems (135 307) Dianova (ABR-38586) ATS Bio (AB-N40) Synaptic

(12) Methyl-4-phenylpyridinium (MPP+) differentially affects monoamine release and re-uptake in murine embryonic stem cell-derived dopaminergic and serotonergic neuronsMolecular and cellular neurosciencesSeptember 1, 2017Martí Y, Matthaeus F, Lau T, Schloss P.

(13) Development of early-born γ-Aminobutyric acid hub neurons in mouse hippocampus from embryogenesis to adulthoodThe Journal of comparative neurologyAugust 15, 2016Villette V, Guigue P, Picardo MA, Sousa VH, Leprince E, Lachamp P, Malvache A, Tressard T, Cossart R, Baude A.rabbit, 139 103, AB_887864",1:500 VMaT2,Rat VMaT2 (496–515 aa),"Synaptic Systems, polyclonal rabbit, 138 302, AB_2270299",1:500 Antibodies Used To Label EBGNs in Mouse Forebrain

(14) Harnessing the trophic and modulatory potential of statins in a dopaminergic cell lineSynapse (New York, N.Y.)March 1, 2016Schmitt M, Dehay B, Bezard E, Garcia-Ladona FJ.

(15) Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brainNeurotoxicologySeptember 1, 2015Dervola KS, Johansen EB, Walaas SI, Fonnum F.

(16) Dopaminergic and glutamatergic microdomains in a subset of rodent mesoaccumbens axonsNature neuroscienceMarch 1, 2015Zhang S, Qi J, Li X, Wang HL, Britt JP, Hoffman AF, Bonci A, Lupica CR, Morales M.(ab81855; Abcam, 1:500); Rb-anti-VMAT2 (VMAT2-Rb-Af720; Frontier Institute Co. Ltd, 1:1000); Rb-anti-VMAT2 (138302; Synaptic Systems, Germany, 1:1000); Rb-anti-VMAT2 (AB1598P; EMD Millipore, 1:1000 dilution); Gt-anti-VMAT2

(17) GABA is localized in dopaminergic synaptic vesicles in the rodent striatumBrain structure & functionNovember 1, 2014Stensrud MJ, Puchades M, Gundersen V.

(18) Distribution of VGLUT3 in highly collateralized axons from the rat dorsal raphe nucleus as revealed by single-neuron reconstructionsPloS oneJanuary 1, 2014Gagnon D, Parent M.other antibody.Incubation with blocking peptideabolished labeling,[66] Rabbit α VMAT2,Synaptic System,138 302,1∶ 1000,Single strong band at 55 kDa on Westernblots of brainstem preparation,Single strong band at

(19) Sympathetic fiber sprouting in inflamed joints and adjacent skin contributes to pain-related behavior in arthritisThe Journal of neuroscience : the official journal of the Society for NeuroscienceJune 12, 2013Longo G, Osikowicz M, Ribeiro-da-Silva A.

(20) Cytoprotective effects of growth factors: BDNF more potent than GDNF in an organotypic culture model of Parkinson's diseaseBrain researchMarch 10, 2011Stahl K, Mylonakou MN, Skare Ø, Amiry-Moghaddam M, Torp R.

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VMaT2 antibody

VMaT2 antibody

VMaT2 antibody

VMaT2 antibody from Synaptic Systems GmbH

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Questions and Answers

Synaptic Systems GmbH

Citations (24)

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VMaT2 antibody from Synaptic Systems GmbH

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