MuSK Antibody AF3904 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMuSK Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF3904
ApplicationsWestern Blot
Quantity100 ug (also 25 ug)
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityHuman,Mouse
IsotypeIgG
TargetMuSK
Conjugate/TagUnconjugated
HostGoat
NCBI Full Gene Namemuscle associated receptor tyrosine kinase
ClonalityPolyclonal
ImmunogenMouse myeloma cell line NS0-derived recombinant human MuSK, Glu22-Ser503, Accession # O15146
ConcentrationLYOPH
PurityAntigen Affinity-purified
NCBI Gene AliasesCMS9, FADS, FADS1
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Detects human MuSK in direct ELISAs and Western blots. In direct ELISAs, less than 40% cross-reactivity with recombinant rat MuSK is observed.

Sizes Available: 100 ug (also 25 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibodyeLifeFebruary 20, 2018Cantor S, Zhang W, Delestrée N, Remédio L, Mentis GZ, Burden SJ.AB_2298772 antibody Rabbit anti-MuSK Burden lab PMID: 10781064 antibody Goat anti-MuSK R and D Systems Cat# AF3904, RRID:AB_2147242 antibody Rabbit anti-Dok-7 Burden lab PMID: 18848351 antibody Mouse anti-phosphotyrosine

(2) Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster FormationMolecular and cellular biologyJanuary 15, 2016Hallock PT, Chin S, Blais S, Neubert TA, Glass DJ.gift from Steven Burden (NYU), or immunoblotted with antibodies to the extracellular domain of MuSK (AF3904; R&D Systems). Dok-7 was immunoprecipitated with rabbit antiserum directed against the C terminus (12)

(3) Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-LGenes & developmentNovember 1, 2010Hallock PT, Xu CF, Park TJ, Neubert TA, Curran T, Burden SJ.of MuSK (Herbst and Burden 2000) and was detected by probing Western blots with antibodies to MuSK (AF3904 from R&D Systems). A monoclonal antibody to the AChR subunit (mab124) was the kind gift of Dr. J. Lindstrom

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Human MuSK Antibody

MuSK Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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MuSK Antibody from R&D Systems, a Bio-Techne Brand

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