VGLUT3 antibody 135 203 from Synaptic Systems GmbH

Product Specs
ItemVGLUT3 antibody
CompanySynaptic Systems GmbH
Price $405.00Supplier Page View Company Product Page
Catalog Number135 203
Hostrabbit
Reactivityrat, mouse
ApplicationsWB, IHC, IHC-P, FACS
Quantity50 µg
TargetVGLUT3
Clonalitypolyclonal
ValidationKO, KD
Purityaffinity purified
ImmunogenRecombinant protein corresponding to AA 543 to 601 from mouse VGLUT3
Antibody TypePrimary antibody
Formatlyophilized

Questions and Answers

What applications has the VGLUT3 antibody been used for in scientific research?

The VGLUT3 antibody has been shown to work in various applications including Western Blotting, Flow Cytometry, Immunocytochemistry, and Immunohistochemistry. It has been utilized in studies examining the role of vesicular glutamate transporter type 3 in social behavior and sensory neuron activation, among other applications.

Can this antibody be used to study the role of VGLUT3 in specific brain regions?

Yes, the VGLUT3 antibody has been used in immunohistochemistry to investigate the distribution and function of VGLUT3-positive neurons in the median raphe region, which is implicated in social behavior and anxiety regulation. Studies have demonstrated its effectiveness in identifying VGLUT3 expression in relevant neuronal populations.

Is the VGLUT3 antibody effective in knockout models?

The VGLUT3 antibody has been validated for use in knockout models, as indicated by its application in studies involving VGluT3 knockout mice. These studies have explored the behavioral and neuronal activation changes associated with the absence of VGLUT3, providing insights into its functional significance.

What species does the VGLUT3 antibody react with?

The VGLUT3 antibody is reactive with mouse and rat tissues, making it suitable for studies involving these species in various experimental contexts, including behavioral assays and neuronal characterization.

Synaptic Systems GmbH

Rudolf-Wissell-Str. 28

Goettingen 37079

Germany

Phone: +49-551-50556-0
+49-551-50556-384

Company Profile

Website: http://www.sysy.com/

(1) Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearingSci AdvOctober 17, 2025Han Chen, Constantin Cretu, Abigail Trebilcock, Natalia Evdokimova, Norbert Babai, Laura Feldmann, Florian Leidner, Fritz Benseler, Sophia Mutschall, Klara Esch, et al.otoferlin, chicken anti-parvalbumin (Synaptic Systems, #195006) or rabbit anti-Vglut3 (Synaptic Systems, #135203) was used as a context marker to label IHCs, mouse anti-ctbp2 (BD Biosciences, #612044), and rabbit

(2) Heterozygous TBX2 frameshift variants cause a novel syndromic hearing loss with incompletely penetrant nystagmusJ Med GenetSeptember 17, 2025Wan Hua, Yanfei Wang, Xiang Li, Wenyu Xiong, Lanchen Wang, Meilin Chen, Fengxiao Bu, Libo Liu, Fangyi Chen, Mingjun Zhong, et al.antibodies used included goat polyclonal anti-Prestin (sc-22692, Santa Cruz), rabbit polyclonal anti-vGlut3 (135203, Synaptic Systems) and mouse monoclonal anti-Otoferlin (ab53233, Abcam). Immunofluorescence images were

(3) Regulation of perisomatic synapses from cholecystokinin basket interneurons through NrCAM and Ankyrin BCurr Res NeurobiolJune 1, 2025Oldre EN, Webb BD, Sperringer JE, Maness PF.antibody (Novus Biologicals NBP2-50038, 1 mg/ml) and 1:500 rabbit anti-VGLUT3 antibody (Synaptic Systems 135203, 1 mg/ml); or 1:2500 rabbit anti-NECAB1 antibody (Sigma HPA023629, 0.20 mg/ml). Mouse monoclonal antibody

(4) DLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive AutophagyAging CellMay 12, 2025Rui Ding, Weiyi Huang, Chenling Shen, Yi Pan, Yiming Zhong, Bing Kong, Yilin Shen, Mingliang Xiang, Bin Yeimmunofluorescence analysis: Prestin (Santa Cruz Biotechnology, sc‐293212; 1:500), vglut3 (Synaptic Systems, 135203; 1:500), p‐JNK (Santa Cruz Biotechnology, sc‐6254; 1:300), donkey anti‐rabbit 568 (Thermo Fisher Scientific,

(5) Synaptic vesicle-omics in mice captures signatures of aging and synucleinopathyNat CommunMay 1, 2025Virginia Gao, Julita Chlebowicz, Karlton Gaskin, Juan A. Briano, Lauren E. Komer, André Pineda, Shrey Jhalani, Saad Ahmad, Eseosa Uwaifo, Luca S. Black, et al.1:500), vGluT2 (Synaptic Systems Cat# 135 402, RRID:AB_2187539, 1:500), vGluT3 (Synaptic Systems Cat# 135 203, RRID:AB_887886, 1:500), vMAT2 (Santa Cruz Biotechnology Cat# sc-374079, RRID:AB_10917928, 1:500). Quantification

(6) Slick potassium channels limit TRPM3-mediated activation of sensory neuronsFrontiers in PharmacologyDecember 18, 2024Patrick Engel, Fangyuan Zhou, Bang Tam Thi Tran, Achim Schmidtko, Ruirui Lupeptide,"CGRP; 1:800, #PC205L, Sigma-Aldrich" rabbit anti-vesicular glutamate transporter 3,"VGLUT3, 1:100, #135203, Synaptic Systems" mouse anti-Slick,"1:500, clone N11/33, #75-055, antibodiesinc" goat anti-mouse

(7) Feedforward inhibition of stress by brainstem neuropeptide Y neuronsNature communicationsSeptember 1, 2024Zhang Y, Shen J, Xie F, Liu Z, Yin F, Cheng M, Wang L, Cai M, Herzog H, Wu P, et al.(Cell Signaling Technology, 2250, 1:1000), rabbit anti-NPY (Abcam, ab30914, 1:1000), rabbit anti-VGLUT3 (Synaptic Systems, 135203, 1:500), rabbit anti-5-HT (ImmunoStar, 20080, 1:500) and rabbit anti-Tyrosine Hydroxylase (Merck Millipore,

(8) Deletion of the Ebf1, a mouse deafness gene, causes a dramatic increase in hair cells and support cells of the organ of CortiDevelopment (Cambridge, England)August 15, 2024Powers KG, Wilkerson BA, Beach KE, Seo SS, Rodriguez JS, Baxter AN, Hunter SE, Bermingham-McDonogh O.

(9) The human VGLUT3-pT8I mutation elicits uneven striatal DA signaling, food or drug maladaptive consumption in male miceNature communicationsJuly 7, 2024Favier M, Martin Garcia E, Icick R, de Almeida C, Jehl J, Desplanque M, Zimmermann J, Henrion A, Mansouri-Guilani N, Mounier C, et al.

(10) The Role of Vesicular Glutamate Transporter Type 3 in Social Behavior, with a Focus on the Median Raphe RegioneNeuroJune 1, 2024Fazekas CL, Török B, Correia P, Chaves T, Bellardie M, Sipos E, Horváth HR, Gaszner B, Dóra F, Dobolyi Á, et al.slides were incubated in anti-RFP (1:1,000, rat, #5f8-100, ChromoTek) and anti-VGluT3 (1:600, rabbit, #135203, Synaptic Systems) primer solutions on 4°C, then in secondary anti-rabbit antibody conjugated with Alexa-488

(11) Excessive processing and acetylation of OPA1 aggravate age‐related hearing loss via the dysregulation of mitochondrial dynamicsAging CellApril 1, 2024Andi Zhang, Yi Pan, Hao Wang, Rui Ding, Tianyuan Zou, Dongye Guo, Yilin Shen, Peilin Ji, Weiyi Huang, Qing Wen, et al.followed by incubation with anti‐Prestin (Santa Cruz, sc‐22692) and anti‐vGlut3 (Synaptic Systems, 135203) primary antibodies at 4°C overnight. Then, the samples were incubated with fluorescent secondary antibodies

(12) Spatial proteomics in neurons at single-protein resolutionCellMarch 28, 2024Unterauer EM, Shetab Boushehri S, Jevdokimenko K, Masullo LA, Ganji M, Sograte-Idrissi S, Kowalewski R, Strauss S, Reinhardt SCM, Perovic A, et al.

(13) EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear DevelopmentThe Journal of neuroscience : the official journal of the Society for NeuroscienceFebruary 14, 2024Kagoshima H, Ohnishi H, Yamamoto R, Yasumoto A, Tona Y, Nakagawa T, Omori K, Yamamoto N.

(14) Proteomic Analysis Reveals the Composition of Glutamatergic Organelles of Auditory Inner Hair CellsMolecular & cellular proteomics : MCPFebruary 1, 2024Cepeda AP, Ninov M, Neef J, Parfentev I, Kusch K, Reisinger E, Jahn R, Moser T, Urlaub H.anti-otoferlin [13A9] (ab53233, Abcam), rabbit anti-otoferlin (178003, Synaptic Systems), rabbit anti-VGluT3 (135203, Synaptic Systems), guinea pig anti-VGluT3 (135204, Synaptic Systems), mouse anti-synapsin-1 (106001,

(15) Inhibitory CCK+ basket synapse defects in mouse models of dystroglycanopathyeLifeJanuary 5, 2024Jahncke JN, Miller DS, Krush M, Schnell E, Wright KM.,Synaptic Systems,131–003,AB_887869 VGAT,Guinea Pig,1:500,Synaptic Systems,131–005,AB_1106810 VGlut3,Rabbit,1:1000,Synaptic Systems,135–203,AB_887886 VIP,Rabbit,1:1000,ImmunoStar,20077,AB_572270 Primary antibodies used for immunohistochemistry.

(16) In situ regeneration of inner hair cells in the damaged cochlea by temporally regulated co-expression of Atoh1 and Tbx2Development (Cambridge, England)December 15, 2023Li X, Ren M, Gu Y, Zhu T, Zhang Y, Li J, Li C, Wang G, Song L, Bi Z, et al.

(17) Probing the role of the C2F domain of otoferlinFront Mol NeurosciDecember 12, 2023Han Chen, Qinghua Fang, Fritz Benseler, Nils Brose, Tobias Moser(polyclonal),Synaptic Systems,1:500,160002 Anti-Vglut3,Rabbit (polyclonal),Synaptic Systems,1:300,135203 Anti-GM130,Mouse (monoclonal IgG1),BD Biosciences,1:200,610822 Secondary antibody,Secondary antibody,Secondary

(18) The proper timing of Atoh1 expression is pivotal for hair cell subtype differentiation and the establishment of inner ear functionCellular and Molecular Life SciencesDecember 1, 2023Dan You, Wenli Ni, Yikang Huang, Qin Zhou, Yanping Zhang, Tao Jiang, Yan Chen, Wenyan Li(1:300, Santa Cruz Biotechnology, Cat# sc-22692), rabbit anti-VGLUT3 (1:300, Synaptic Systems, Cat# 135203), mouse anti-PARVALBUMIN (1:800, Sigma, Cat# P3088), mouse anti-TUJ1 (1:1000, Sigma, Cat#T2200), mouse

(19) A glutamatergic DRN-VTA pathway modulates neuropathic pain and comorbid anhedonia-like behavior in miceNature communicationsAugust 23, 2023Wang XY, Jia WB, Xu X, Chen R, Wang LB, Su XJ, Xu PF, Liu XQ, Wen J, Song XY, et al.anti-TPH2 (1:500, rabbit, Abcam, Cat# ab111828), anti-VGluT3 (1:500, rabbit, Synaptic Systems, Cat# 135203), anti-GABA (1:500, rabbit, Sigma, Cat# A2052), anti-TH (1:1000, rabbit, Emd Millipore, Cat# AB152).

(20) Interrelationships Between Spinal Sympathetic Preganglionic Neurons, Autonomic Systems and Electrical Synapses Formed by Connexin36-containing Gap JunctionsNeuroscienceJuly 15, 2023Recabal-Beyer A, Tavakoli H, Senecal JMM, Stecina K, Nagy JI.

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VGLUT3 antibody

VGLUT3 antibody

VGLUT3 antibody

VGLUT3 antibody from Synaptic Systems GmbH

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Questions and Answers

Synaptic Systems GmbH

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VGLUT3 antibody from Synaptic Systems GmbH

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