P2X7 Antibody 177 003 from Synaptic Systems GmbH

Product Specs
ItemP2X7 Antibody
CompanySynaptic Systems GmbH
Price $380.00Supplier Page View Company Product Page
Catalog Number177 003
Quantity50 µg
ApplicationsWB
Purityaffinity purified
Reactivityrat, mouse
TargetP2X7
Hostrabbit
ImmunogenRecombinant protein corresponding to AA 363 to 595 from mouse P2X7
Clonalitypolyclonal
ValidationKO

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Synaptic Systems GmbH

Rudolf-Wissell-Str. 28

Goettingen 37079

Germany

Phone: +49-551-50556-0
+49-551-50556-384

Company Profile

Website: http://www.sysy.com/

(1) Establishment and behavioural characterization of a novel constitutive P2X7 receptor knockout mouse linePurinergic SignallingOctober 1, 2025Iven-Alex von Mücke-Heim, Judit Oldekamp, Michael W. Metzger, Sarah Kläffgen, Hao Tang, Sandra M. Walser, Nina Dedic, Gerhard Rammes, Florian Holsboer, Wolfgang Wurst, et al.polyclonal rabbit antibody directed against the C-terminal domain of P2X7 (Synaptic Systems, Cat no #177,003; 1:1000). A polyclonal rabbit antibody against βactin (Cell SignallingTechnoloct Cat no # 4967; 1:2000)

(2) Spatiotemporal diversity in molecular and functional abnormalities in the mdx dystrophic brainMol MedMarch 20, 2025Joanna Pomeroy, Malgorzata Borczyk, Maria Kawalec, Jacek Hajto, Emma Carlson, Samuel Svärd, Suraj Verma, Eric Bareke, Anna Boratyńska-Jasińska, Dorota Dymkowska, et al.shown in Table 1. Antibodies The following antibodies were used for Western blotting: anti-P2X7 (177003, Synaptic Systems), anti-P2X4 (APR-002, Alomone Labs), and anti-GLUT3+14 (ab191071, Abcam) at a 1:1000

(3) P2X7R antagonism suppresses long-lasting brain hyperexcitability following traumatic brain injury in miceTheranosticsJanuary 27, 2025Mariana Alves, Laura de Diego-Garcia, Gloria Vegliante, Oscar Moreno, Beatriz Gil, Pedro Ramos-Cabrer, Meghma Mitra, Ana Fernandez Martin, Aida Menéndez-Méndez, Yitao Wang, et al.directed against epitope AA 363 to 595 of mouse P2X7Rs, Synaptic System, Göttingen, Germany; Cat #: 177003), P2X7R intracellular (1:400, rabbit IgG; Alomone Labs, directed against epitope AA 576-595 of rat P2X7R,

(4) P2X7 Purinoceptor Affects Ectopic Calcification of Dystrophic MusclesFrontiers in PharmacologyJuly 14, 2022Robin M. H. Rumney, Justyna Róg, Natalia Chira, Alexander P. Kao, Rasha Al-Khalidi, Dariusz C. GóreckiLaboratories IVD) in PBS for 1 h at RT and incubated overnight at 4°C with primary antibodies (anti-P2X7; 177003, Synaptic Systems, anti-TAG, PA1-984B, Invitrogen and marker of macrophages anti-F4/80; ab6640, Abcam

(5) iTRAQ-based proteomics implies inflammasome pathway activation in the prefrontal cortex of CSDS mice may influence resilience and susceptibilityLife sciencesDecember 1, 2020Lan T, Bai M, Chen X, Wang Y, Li Y, Tian Y, He Y, Wu Z, Yu H, Chen Z, et al.

(6) Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobodyeLifeAugust 3, 2018Kaczmarek-Hajek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, Bruzzone S, Engel T, Jooss T, Krautloher A, et al.et al., Nat Genet. 2003",MGI:3051635,CNP-Cre Antibody,P2X7 C-term (rb pAb),Synaptic Systems,"Cat# 177003, RRID: AB_887755",WB 1:1500 IHC 1:500 Antibody,P2X7 ECD (rb pAb),Alomone,Cat# APR-008 RRID:AB_2040065,WB

(7) Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibitionJournal of molecular cell biologyJune 1, 2018Young CNJ, Chira N, Róg J, Al-Khalidi R, Benard M, Galas L, Chan P, Vaudry D, Zablocki K, Górecki DC.

(8) P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophyPLoS medicineOctober 1, 2015Sinadinos A, Young CN, Al-Khalidi R, Teti A, Kalinski P, Mohamad S, Floriot L, Henry T, Tozzi G, Jiang T, et al.polyclonal, and GAPDH—G9545 (Sigma-Aldrich); collagen type-IV—AB769, goat polyclonal (Chemicon); P2X7–177 003, rabbit polyclonal (Synaptic Systems); β-tubulin—IMG-5810A, rabbit polyclonal (Imgenex); dystrophin—2166,

(9) A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90AutophagyJanuary 1, 2015Young CN, Sinadinos A, Lefebvre A, Chan P, Arkle S, Vaudry D, Gorecki DC.G7513). Antibodies and reagents The following antibodies were used: anti-P2RX7 (Synaptic Systems, 177003) 1:1000, anti-MAPK1-MAPK3 (Cell Signaling Technology, 9102) 1:2000, anti-phospho-MAPK1-MAPK3 (Cell Signaling Technology

(10) P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatmentJournal of cellular and molecular medicineMay 1, 2012Young CN, Brutkowski W, Lien CF, Arkle S, Lochmüller H, Zabłocki K, Górecki DC.for immunohistochemistry or Western blot analyses. Antibodies The following antibodies were used: P2X7-177003, rabbit polyclonal (Synaptic Systems, Goettingen, Germany), immunohistochemistry (IH) and Western blotting

(11) Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockoutsBritish journal of pharmacologyFebruary 1, 2012Masin M, Young C, Lim K, Barnes SJ, Xu XJ, Marschall V, Brutkowski W, Mooney ER, Gorecki DC, Murrell-Lagnado R.

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P2X7 Antibody

P2X7 Antibody from Synaptic Systems GmbH

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Synaptic Systems GmbH

Citations (11)

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P2X7 Antibody from Synaptic Systems GmbH

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