Mouse/Rat Integrin alpha 8 Antibody AF4076 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemMouse/Rat Integrin alpha 8 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $499.00Supplier Page View Company Product Page
Catalog NumberAF4076
Quantity100 ug (also 25 ug)
ApplicationsFlow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Simple Western,Neutralization,Immunocytochemistry
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
Conjugate/TagUnconjugated
ConcentrationLYOPH
PurityAntigen Affinity-purified
TargetIntegrin alpha 8
IsotypeIgG
ReactivityCanine,Human,Mouse,Rat,Transgenic Mouse
HostGoat
Antibody TypePrimary Antibodies
ClonalityPolyclonal
ImmunogenChinese hamster ovary cell line CHO-derived recombinant mouse Integrin alpha 8, Phe38-Phe1007, Accession # A28ARA8
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Nameintegrin alpha 8

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) A multi-omic single-cell landscape of perinatal mouse skin maps lineage specification and reveals shared dynamics in human fetal skinExperimental & Molecular MedicineApril 17, 2026Hanjae Lee, Seunghee Lee, Seong Jin Jo, Sunhyoung Lee, Hyunjung Go, Ohsang Kwon, Jong-Il Kimovernight at 4 °C with primary antibodies against Mef2c (R&D Systems, AF6786) and Itga8 (R&D Systems, AF4076). The following day, sections were washed with PBS and incubated with species-appropriate secondary

(2) Glomerular basement membrane structural integrity dictates trans-tissue deposition of laminin in the kidneyCell ReportsMarch 24, 2026Kohei Omachi, Meei-Hua Lin, Pongpratch Puapatanakul, Joshua F. Begin, Karen K. McKee, Hironobu Fujiwara, Peter D. Yurchenco, Jeffrey H. Mineranti-COL4A1/2 (Southern Biotech, #1340–01, 1:200 dilution), and polyclonal goat anti-integrin-α8 (R&D Systems, #AF4076, 1:100 dilution). Fluorescent images were acquired on a Nikon C1 confocal microscopy. For near super

(3) Hyperinnervation inhibits organ-level regeneration in mammalian skinCellMarch 20, 2026Hannah T. Tam, Jingyu Peng, Rebecca Freeman, Yulia Shwartz, Shlomi Brielle, Sakshi Garg, Siti Rahmayanti, Stephen J. Crocker, Devin Coon, Ya-Chieh Hsuanti GFP (1:500),Abcam,Cat#ab6662;RRID:AB_305635 Goat anti Integrin alpha 8 (1:100),R&D Systems,Cat#AF4076;RRID:AB_2296280 Goat anti Myeloperoxidase (1:50),R&D Systems,Cat#AF3667;RRID:AB_2250866 Goat anti

(4) Vascular Endothelial Growth Factor-D Improves Lung Vascular Integrity During Acute Lung InjuryCirc ResMarch 13, 2026Yongdae Yoon, Lokesh Sharma, Wenwen Tang, Shannon Kirk, Micha Sam Brickman Raredon, Farida Ahangari, Johad Khoury, Hong Qian, Yunbo Ke, Mohan Tulapurkar, et al.(Thermo Fisher Scientific, # PA5-13300), VEGFR2 (Santa Cruz Biotechnology, # sc-6251), ITGA8 (Novus Biologicals, # AF4076), PRX (Novus Biologicals, # NBP1-89598) overnight at 4 °C followed by staining with secondary antibodies

(5) Vascular Endothelial Growth Factor-D Improves Lung Vascular Integrity During Acute Lung InjuryCirc ResMarch 13, 2026Yongdae Yoon, Lokesh Sharma, Wenwen Tang, Shannon Kirk, Micha Sam Brickman Raredon, Farida Ahangari, Johad Khoury, Qian Hong, Yunbo Ke, Mohan Tulapurkar, et al.(Thermo Fisher Scientific, # PA5-13300), VEGFR2 (Santa Cruz Biotechnology, # sc-6251), ITGA8 (Novus Biologicals, # AF4076), PRX (Novus Biologicals, # NBP1-89598) overnight at 4 °C followed by staining with secondary antibodies

(6) Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunityCellJanuary 8, 2026Emily Scott-Solomon, Shlomi Brielle, Alexander O. Mann, Mark J. Khoury, Jingyu Peng, Liana Tellez, Mackenzie Harrigan, Myrto Ziogas, H. Amalia Pasolli, Monica Cassandras, et al.,Cell Signaling Technology,Catalog# 9664S; RRID:AB_2070042 Goat anti Integrin alpha 8 (1:200),R&D Systems,Catalog# AF4076; RRID:AB_2296280 Goat anti P-cadherin (1:200),R&D Systems,Catalog# AF761; RRID:AB_355581 Goat anti

(7) Mouse Alport podocytes are susceptible to AAV9 transduction in vivoKidney InternationalJanuary 1, 2026Meei-Hua Lin, Kohei Omachi, Joshua F. Begin, Jennifer L. Richardson, Jeffrey H. Miner7078), 1:50 for collagen α1α1α2(IV) (SouthernBiotech, 1340–01), 1:100 for Integrin α8 (R&D Systems, AF4076), and 1:100 for SLC12A1 (Abcam, ab171747). For sections from fresh frozen tissues, 1:200 was used for

(8) Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier IntegrityAdvanced ScienceOctober 14, 2025Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, et al.Antibody,Brand,Catalog number,Dilution Goat polyclonal anti‐Integrin alpha 8,RD R&D Systems (RD),AF4076,1:500 Rat monoclonal anti‐CD31,BD Biosciences,550274,1:200 Goat polyclonal anti‐CD31,RD,AF3628,1:300 Rabbit

(9) Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modelingCell Stem CellOctober 2, 2025Biao Huang, Pedro Medina, Jincan He, Zipeng Zeng, Sunghyun Kim, Janet Romo, Kari Koppitch, Chennan C. Zhang, Georgina Gyarmati, Yohan Park, et al.previously.10,14 Since iPSC lines do not have SIX2-GFP reporter, ITGA8 antibody (R&D Systems, Cat# AF4076) was used to enrich iNPCs after iPSC differentiation. c-Kit antibody (BioLegend, Cat# 313204) was used

(10) Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and diseaseCell Stem CellJune 6, 2024Biao Huang, Zipeng Zeng, Sunghyun Kim, Connor C. Fausto, Kari Koppitch, Hui Li, Zexu Li, Xi Chen, Jinjin Guo, Chennan C. Zhang, et al.counted and diluted to 1 million cells per 100 μl in FACS medium, and ITGA8 antibody (R&D Systems, # AF4076) was added at the ratio of 1:200 for live cell staining. The incubation with ITGA8 antibody was performed

(11) Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensationbioRxiv : the preprint server for biologyFebruary 8, 2024Liu J, Prahl LS, Huang A, Hughes AJ.

(12) Rho/ROCK activity tunes cell compartment segregation and differentiation in nephron-forming nichesbioRxiv : the preprint server for biologyNovember 10, 2023Viola JM, Liu J, Huang A, Grindel SH, Prahl LS, Hughes AJ.

(13) SOX9 Modulates the Transformation of Gastric Stem Cells Through Biased Symmetric Cell DivisionGastroenterologyJune 1, 2023Chen Q, Weng K, Lin M, Jiang M, Fang Y, Chung SSW, Huang X, Zhong Q, Liu Z, Huang Z, et al.A-11122, Thermofisher), goat anti-tdTomato (1:1000, orb182397, biorbyt), mouse anti-Integrin-α8 (1:100, AF4076, R&D Systems), mouse anti-γ-tubulin (1:500, T6557, MilliporeSigma), rabbit anti-Aurora B(1:200, A19539,

(14) Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoidsbioRxiv : the preprint server for biologyMay 25, 2023Huang B, Zeng Z, Li H, Li Z, Chen X, Guo J, Zhang CC, Schreiber ME, Vonk AC, Xiang T, et al.counted and diluted to 1 million cells per 100 µl in FACS medium, and ITGA8 antibody (R&D Systems, # AF4076) was added at the ratio of 1:200 for live cell staining. The incubation with ITGA8 antibody was performed

(15) Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regressionNature cell biologyFebruary 1, 2023Martino P, Sunkara R, Heitman N, Rangl M, Brown A, Saxena N, Grisanti L, Kohan D, Yanagisawa M, Rendl M.

(16) Chromatin accessibility and microRNA expression in nephron progenitor cells during kidney developmentGenomicsJanuary 1, 2022Clugston A, Bodnar A, Cerqueira DM, Phua YL, Lawler A, Boggs K, Pfenning AR, Ho J, Kostka D.(Dynabeads FlowComp Flexi kit, ThermoFisher 11061D) biotinylated to antibodies for Integrin alpha 8 (Itgα8, R&D Systems AF4076) using the DSB-X Biotin Protein Labeling Kit (ThermoFisher D-20655). Nephron progenitors bound to these

(17) Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate woundseLifeSeptember 29, 2020Phan QM, Fine GM, Salz L, Herrera GG, Wildman B, Driskell IM, Driskell RR.Genomics Cat#: PN-120267 Antibody Anti-Integrin alpha 8 (Itga8) (goat polyclonal) R and D Systems Cat#: AF4076 IF(1:200) Antibody Anti-Pref1/Dlk1 (rabbit monoclonal) R and D Systems Cat#: AF8277 IF(1:200) Antibody Anti-Dpp4/CD26 (goat

(18) Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound HealingCell stem cellSeptember 3, 2020Abbasi S, Sinha S, Labit E, Rosin NL, Yoon G, Rahmani W, Jaffer A, Sharma N, Hagner A, Shah P, et al.

(19) Co-immunostaining of ICAM-1, ICAM-2, and CD31 in Mouse Kidney GlomeruliBio-protocolJuly 5, 2020Sung SJ.(R&D Systems, catalog number: AF3159) b. Anti-mouse Integrin α8 (Itgα8) (R&D Systems, catalog number: AF4076) c. Anti-mouse CD31 (R&D Systems, catalog number: AF3628) 19. Monoclonal anti-mouse Ab: a. Rat mAb:

(20) Molecular characterization of nephron progenitors and their early epithelial derivative structures in the nephrogenic zone of the canine fetal kidneyEuropean journal of histochemistry : EJHSeptember 23, 2019Faraj R, Irizarry-Alfonzo A, Puri P.16960; Cell Signaling), SIX2 (1:1000, 11562-1-AP; Protein Tech, Rosemont, IL, USA) and ITGA8 (1:500, AF4076; R&D Systems, Minneapolis, MN, USA), Alexa Fluor 594 and Alexa Fluor 488 secondary antibodies were used

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Integrin alpha 8 Antibody

Integrin alpha 8 Antibody

Integrin alpha 8 Antibody

Integrin alpha 8 Antibody

Integrin alpha 8 Antibody

Mouse/Rat Integrin alpha 8 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Mouse/Rat Integrin alpha 8 Antibody from R&D Systems, a Bio-Techne Brand

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