Biorbyt's KAISO (N) Antibody, Rabbit Polyclonal is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The KAISO (N) Antibody, Rabbit Polyclonal was generated using ZBTB33 as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
Rabbit polyclonal to KAISO.KAISO is also known as Zinc finger and BTB domain-containing protein 33, a transcriptional regulatorwith bimodal DNA-binding specificity. KAISO binds to methylated CpG dinucleotides in theconsensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. KAISO can recruits the N-CoR repressor complex to promote histone deacetylation andthe formation of repressive chromatin structures in target gene promoters. In contrast, KAISO mayalso activate transcription of a subset of target genes by the recruient of CTNND2