Anti-ADAMTS5 antibody ab41037 from Abcam

Product Specs
ItemAnti-ADAMTS5 antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab41037
Antibody TypePrimary
IsotypeIgG
ApplicationsWestern blot
ClonalityPolyclonal
Quantity100 UG
HostRabbit
Conjugate/TagUnconjugated
Concentration1 mg/ml
Gene NameADAMTS5
ReactivityHuman, Mouse, Rat
TargetADAMTS5

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb SuspensionCartilageDecember 1, 2023Takahashi I, Matsuzaki T, Kuroki H, Hoso M.Japan) and A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5; diluted 1:50, ab41037; Abcam, Tokyo, Japan). For type 2 collagen, the staining intensity was calculated in the same manner

(2) Inhibition of miR-96-5p alleviates intervertebral disc degeneration by regulating the peroxisome proliferator-activated receptor γ/nuclear factor-kappaB pathwayJ Orthop Surg ResDecember 1, 2023Xusheng Li, Qian Hou, Wenqi Yuan, Xuehua Zhan, Haifeng Yuanmetalloproteinase with thrombospondin motifs type 4 (ADAMTS-4) (ab185722, 1:1,000, Abcam), anti-ADAMTS-5 (ab41037, 1:250, Abcam), anti-NF-κB (ab32360, 1:1,000, Abcam), anti-β-actin (ab8226, 1:1,000, Abcam), and anti-H3

(3) TAF15 regulates the BRD4/GREM1 axis and activates the gremlin-1-NF-κB pathway to promote OA progressionRegenerative therapyDecember 1, 2023Du X, Xin R, Chen X, Wang G, Huang C, Zhou K, Zhang S.ab32503), Bcl-2 (Abcam, 1:1000, ab182858), MMP13 (Abcam, 1:1000, ab39012), ADAMTS5 (Abcam, 1:1000, ab41037), Collagen II (Abcam, 1:1000, ab34712), Aggrecan (Abcam, 1:1000, ab3778), BRD4 (Abcam, 1:1000, ab128874),

(4) Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammationArthritis Research & TherapyNovember 29, 2023Xin Liu, Huimin Li, Yaping Feng, Huilin Guo, Yingjie Li, Jin Ke, Xing LongGB11119, Servicebio), rabbit anti-COX-2 (1:300, 12375–1-AP, Proteintech), rabbit anti-ADAMTS5 (1:200, ab41037, Abcam), rabbit anti-MMP13 (1:200, 18165–1-AP, Proteintech), rabbit anti-Caspase1 (1:200, BA2220, Boster),

(5) Exosomes from M2c macrophages alleviate intervertebral disc degeneration by promoting synthesis of the extracellular matrix via MiR‐124/CILP/TGF‐βBioengineering & Translational MedicineNovember 1, 2023Yi Liu, Mintao Xue, Yaguang Han, Yucai Li, Bing Xiao, Weiheng Wang, Jiangming Yu, Xiaojian Yeanti‐aggrecan (Abcam, catalog: ab36861), anti‐MMP13 (Abcam, catalog: ab39012), anti‐ADAMTS5 (Abcam, catalog: ab41037), anti‐β‐actin (Cell Signaling Technology, catalog: #4970), anti‐CILP (Thermo Fisher, catalog: PA5‐18553),

(6) PLXNC1 interference alleviates the inflammatory injury, apoptosis and extracellular matrix degradation of IL-1β-exposed chondrocytes via suppressing GRP78 expressionJournal of Orthopaedic Surgery and ResearchOctober 18, 2023Nan Meng, Lingwei Mao, Qinyi Jiang, Jishan Yuan, Linjuan Liu, Lei Wang(cat. no. ab188570; 1/1000; Abcam), ADAMTS-4 (cat. no. ab185722; 1/1000; Abcam), ADAMTS-5 (cat. no. ab41037; 1/250; Abcam), aggrecan (cat. no. GT1267; 1/1000; GeneTex), tubulin (cat. no. ab6046; 1/500; Abcam),

(7) Injectable mesoporous bioactive glass/sodium alginate hydrogel loaded with melatonin for intervertebral disc regenerationMaterials Today BioOctober 1, 2023Ruibang Wu, Leizhen Huang, Qinghong Xia, Zheng Liu, Yong Huang, Yulin Jiang, Juehan Wang, Hong Ding, Ce Zhu, Yueming Song, et al.Abcam), anti-mmp3 antibody (ab52915,1:200; Abcam), anti-MMP-13 (ab219620, 1:200; Abcam), anti-ADAMTS-5 (ab41037, 1:200; Abcam), and anti-β-actin (ab8226, 1:1000; Abcam). Following three washes with TBST, the membranes

(8) An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathologyRedox biologyOctober 1, 2023Ni W, Zhang H, Mei Z, Hongyi Z, Wu Y, Xu W, Ma Y, Yang W, Liang Y, Gu T, et al.were used in this study: anti-MMP13 (1:1000, ab39012, Abcam, Cambridge, UK), anti-ADAMTS5 (1:1000, ab41037, Abcam, Cambridge, UK), anti-SOX9 (1:1000, ab185966, Abcam, Cambridge, UK), anti-ACAN (1:1000, C8035,

(9) Programmable DNA hydrogel provides suitable microenvironment for enhancing autophagy-based therapies in intervertebral disc degeneration treatmentJournal of nanobiotechnologySeptember 28, 2023Qingxin S, Kai J, Dandan Z, Linyu J, Xiuyuan C, Yubo F, Kun W, Yingchao H, Hao C, Jie S, et al.anti-MMP-13 (1:2000, ab92536, Abcam), anti-ADAMTs-4 (1:2000, ab137332, Abcam), anti-ADAMTs-5 (1:5000, ab41037, Abcam), anti-collagen II (1:2000, ab51072, Abcam), anti-ACAN (1:5000, ab3778, Abcam), anti-cleaved

(10) Single-cell transcriptomic analysis of the identity and function of fibro/adipogenic progenitors in healthy and dystrophic muscleiScienceAugust 18, 2023Uapinyoying P, Hogarth M, Battacharya S, Mázala DAG, Panchapakesan K, Bönnemann CG, Jaiswal JK.AF1062 PDGFRα-APC,BioLegend,RRID:AB_2043970; 135908 ADAMTS5 - Rabbit anti-mouse (1:100),Abcam,RRID:AB_2222327; AB41037 DPEP1 - Rabbit anti-human/mouse (1:100),Abcam,RRID:AB_11133237; AB121308 C3 - Rat anti-mouse (1:250),Novus Biologicals

(11) N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progressionCell Commun SignalAugust 10, 2023Zhaowei Lin, Tao Jiang, Wei Zheng, Jiayuan Zhang, Anan Li, Chao Lu, Wengang LiuMaryland, USA). The primary antibodies were as follows: anti-WTAP (ab195380, 1:1000, Abcam), anti-ADAMTS5 (ab41037, 1:250, Abcam), anti-MMP13 (ab39012, 1:3000, Abcam), anti-Collagen II (ab34712, 1:1000, Abcam), anti-Aggrecan

(12) Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosisOpen Life SciAugust 7, 2023Jin Xu, Xiaocheng Zhi, Yunhui Zhang, Ren Dingantibodies against Bax (ab32503, Abcam), Bcl-2 (ab182858, Abcam), MMP13 (ab39012, Abcam), ADAMTS5 (AB41037, Abcam), Col II (ab34712, Abcam), and β-actin (ab8227, Abcam) for 2 h at room temperature. Then, the

(13) Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in miceJournal of orthopaedic translationJuly 1, 2023Zhang P, Jin Y, Xia W, Wang X, Zhou Z.(ab39012), Collagen II (ab34712), HO-1 (ab13243), GAPDH (ab9485), p65 (ab32536), IκBα (ab76429), ADAMTS5 (ab41037), COX-2 (ab179800), iNOS (ab178945) and Lamin B (ab229025) were purchased from Abcam (Cambridge, UK).

(14) Therapeutic potential of melatonin in the intervertebral disc degeneration through inhibiting the ferroptosis of nucleus pulpous cellsJournal of Cellular and Molecular MedicineJune 16, 2023Xinyu Dou, Yunlong Ma, Qipeng Luo, Chunyu Song, Meijuan Liu, Xiao Liu, Donglin Jia, Shuiqing Li, Xiaoguang LiuWuhan, China; rabbit anti‐mouse ADAMTS‐4 (Cat. No. ab185722), rabbit anti‐mouse ADAMTS‐5 (Cat. No. ab41037) that from the Abcam, Cambridge, England; rabbit anti‐mouse anti‐ACSL4 (Cat. No. ab2844946) that from

(15) Urchin-like ceria nanoparticles for enhanced gene therapy of osteoarthritisScience advancesJune 16, 2023Chen H, Ye T, Hu F, Chen K, Li B, Qiu M, Chen Z, Sun Y, Ye W, Wang H, et al.ab36861, Abcam), anti-MMP13 antibodies (1:1000; ab39012, Abcam), and anti-ADAMTs antibodies (1:1000; ab41037, Abcam), followed by incubation with the corresponding horseradish peroxidase–conjugated secondary antibody

(16) ZBTB16 eases lipopolysaccharide‑elicited inflammation, apoptosis and degradation of extracellular matrix in chondrocytes during osteoarthritis by suppressing GRK2 transcriptionExperimental and therapeutic medicineJune 1, 2023Xiong B, Chen L, Huang Y, Lu G, Chen C, Nong J, Pan H.(1:1,000; cat. no. ab233706; Abcam), MMP-13 (1:3,000; cat. no. ab39012; Abcam), ADAMTS-5 (1:250; cat. no. ab41037; Abcam), ACAN (1:1,000; cat. no. NB100-74350; Novus Biologicals, LLC), COL2A1 (1:1,000; cat. no. ab188570;

(17) HTRA1 from OVX rat osteoclasts causes detrimental effects on endplate chondrocytes through NF-κBHeliyonJune 1, 2023Chen L, Zhong Y, Sun S, Yang Z, Hong H, Zou D, Song C, Li W, Leng H.anti-HTRA1,Immunoway,YN2041 Rabbit anti-β-actin,Proteintech,20536-1-AP Mouse anti-Aggrecan,Abcam,ab3773 Rabbit anti-ADAMTS5,Abcam,ab41037 Rabbit anti-MMP13,Abcam,ab39012 Rabbit anti-p65,CST,8242 Alexa Fluor 488-labeled Goat Anti-Rabbit

(18) An injectable liposome-anchored teriparatide incorporated gallic acid-grafted gelatin hydrogel for osteoarthritis treatmentNature communicationsMay 31, 2023Li G, Liu S, Chen Y, Zhao J, Xu H, Weng J, Yu F, Xiong A, Udduttula A, Wang D, et al.US), SOX9 (Cat#ab185966, 1:5000, Abcam, UK), MMP13 (Cat# ab84594, 1:1000, Abcam, UK), ADAMTS5 (Cat#ab41037, 1:250, Abcam, UK), and Gapdh (Cat# AC002, 1:5000, ABclonal, China). Then washed with Tris Buffered

(19) The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritisActa biochimica et biophysica SinicaMay 26, 2023Li W, Tao C, Mao M, Zhu K.Cusabio, Wuhan, China), aggrecan (13880-1-AP; Proteintech), COL2A1 (MA5-12789; Thermo Fisher), ADAMTS-5 (ab41037; Abcam, Cambridge, USA), MMP13 (CSB-PA07029A0Rb; Cusabio), p-p65 (ab194726 for human; Abcam; CSB-PA000582

(20) CKLF1 interference alleviates IL‑1β‑induced inflammation, apoptosis and degradation of the extracellular matrix in chondrocytes via CCR5Experimental and Therapeutic MedicineMay 9, 2023Haoran Wang, Zhongqing Wu, Kanna Xu(1/1,000; cat. no. ab34712), anti-ADAMTS-4 (1/1,000; cat. no. ab185722), anti-ADAMTS-5 (1/250; cat. no. ab41037), anti-CCR5 (1/1,000; cat. no. ab65850) and anti-GAPDH (1/2,500; cat. no. ab9485) antibodies were all

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Anti-ADAMTS5 antibody from Abcam

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Anti-ADAMTS5 antibody from Abcam

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