The ZNRF3 Polyclonal Antibody, Cy7 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to ZNRF3. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The ZNRF3 Polyclonal Antibody, Cy7 Conjugated has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone