The Estrogen Receptor beta (Ser87) Antibody, Cy5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to ESR2, and estrogen receptor 2. This antibody recognizes Mouse antigen. The Estrogen Receptor beta (Ser87) Antibody, Cy5 Conjugated has been shown to work in the following applications: Western Blot.
Description
Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ER alpha and ER beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. ER alpha and ER beta A have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and ER beta may be regulated by distinct mechanisms even though they share many functional characteristics