Bioss Inc.'s BACE1 Polyclonal Antibody, PE-Cy5.5 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, and Western Blot. The BACE1 Polyclonal Antibody, PE-Cy5.5 Conjugated was generated using BACE1, and Beta-Secretase 1 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase