Bioss Inc.'s CLLD8 Polyclonal Antibody, PE-Cy5 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The CLLD8 Polyclonal Antibody, PE-Cy5 Conjugated was generated using SET domain bifurcated histone lysine methyltransferase 2, and SETDB2 as the antigen and it reacts with Rat.
Description
Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis