Phospho-IRS-1 (Ser302) (34C7) Rabbit mAb 2491S from Cell Signaling Technology

Product Specs
ItemPhospho-IRS-1 (Ser302) (34C7) Rabbit mAb
CompanyCell Signaling Technology
Price $397.00 Inquire
Catalog Number2491S
Quantity100 µl
ApplicationsW
ReactivityH, M
TargetIRS-1 (Ser307) phosphate
ModificationsIRS-1 (Ser307) phosphate
HostRabbit
NCBI Gene AliasesHIRS-1
ClonalityMonoclonal
NCBI Full Gene Nameinsulin receptor substrate 1
Research AreaMetabolism
IsotypeIgG
Clone34C7
Molecular Weight180

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Protocol for differentiating murine 3T3-L1 and SVF-derived preadipocytes and isolating crude mitochondrial fractionsSTAR ProtocAugust 23, 2025Churaibhon Wisessaowapak, Jeongmin Lee, Hyeonhui Kim, Seunghwan Son, Xue Feng, Lina Chang, Annie Hoang, Hetty Chen, Sarah Bedsted, Alan R. Saltiel7.8,Sigma-Aldrich,H3375 NaCl,Sigma-Aldrich,71376 MgCl2,Sigma-Aldrich,M8266 Digitonin,Sigma-Aldrich,D141 EDTA,Invitrogen,AM9260G EGTA,EG Scientific,E−2491 RIPA,Cell Signaling Technology,9806 Protease Inhibitor Cocktail,Millipore,539132 Phosphatase Inhibitor

(2) The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst bindingCell reportsMay 25, 2021Kuramoto K, Kim YJ, Hong JH, He C.,Cell Signaling Technology,Cat#3407; RRID:AB_2127860 anti-phospho-IRS-1 (Ser302),Cell Signaling Technology,Cat#2491; RRID:AB_823551 anti-phospho-IRS-1 (Ser636/639),Cell Signaling Technology,Cat#2388; RRID:AB_330339 anti-Akt,Cell Signaling Technology

(3) Structural and functional relationships between plasmodesmata and plant endoplasmic reticulumâ€“plasma membrane contact sites consisting of three synaptotagminsNew PhytologistMay 1, 2020Kazuya Ishikawa, Kentaro Tamura, Yoichiro Fukao, Tomoo Shimadamovement protein cell-to-cell transport. Proceedings of the 559 National Academy of Sciences 107: 2491–2496. 560 Manford AG, Stefan CJ, Yuan HL, MacGurn JA, Emr SD. 2012. ER-to-Plasma 561 Membrane Tethering

(4) Paeoniflorin inhibits cell viability and invasion of liver cancer cells via inhibition of Skp2Oncology LettersMarch 3, 2020Hong Liu, Lili Zang, Jun Zhao, Zhaolin Wang, Lingyun Lianti-β-actin (1:5,000; cat. no. 3700), anti-cyclin dependent kinase inhibitor 1A (p21; 1:1,000; cat. no. 2491) and anti-cyclin dependent kinase inhibitor 1C (p57; 1:1,000; cat. no. 2557) antibodies were obtained

(5) SIRT2 knockout exacerbates insulin resistance in high fat-fed micePloS oneJanuary 1, 2018Lantier L, Williams AS, Hughey CC, Bracy DP, James FD, Ansari MA, Gius D, Wasserman DH.(Cell Signaling 9271; 1:1000), Akt (Cell Signaling 9272; 1:1000), phospho-IRS1 (Ser302) (Cell Signaling 2491; 1:1000), IRS1 (Cell Signaling 2382; 1:1000), phosphoFOXO1 (Ser256) (Cell Signaling 9461; 1:1000), FOXO1

(6) Proteomic Analysis of Dendritic Filopodia-Rich Fraction Isolated by Telencephalin and Vitronectin InteractionFrontiers in synaptic neuroscienceJanuary 1, 2018Furutani Y, Yoshihara Y.

(7) Exposure to an Extremely-Low-Frequency Magnetic Field Stimulates Adrenal Steroidogenesis via Inhibition of Phosphodiesterase Activity in a Mouse Adrenal Cell LinePLOS ONEApril 21, 2016Kazuyoshi Kitaoka, Shiyori Kawata, Tomohiro Yoshida, Fumiya Kadoriku, Mitsuo Kitamura

(8) Carnitine Palmitoyltransferase 1b Deficiency Protects Mice from Diet-Induced Insulin ResistanceJournal of Diabetes & MetabolismApril 1, 2014Teayoun Kim et al.Lowry Protein Assay Kit (Pierce #23240). Primary antibodies were purchased from Cell Signaling; pIRS1 Ser302 (#2491), IRS1 (#2390), pAKT Ser473 (#9271), AKT (#9272), pERK1/2 (p44/42 MAPK) Thr202/Tyr204 (#9101), and ERK1/2

(9) Insulin Responsiveness in Metabolic Syndrome after Eight Weeks of Cycle TrainingMedicine & Science in Sports & ExerciseNovember 1, 2013CHARLES A. STUART, MARK A. SOUTH, MICHELLE L. LEE, MELANIE P. MCCURRY, MARY E. A. HOWELL, MICHAEL W. RAMSEY, MICHAEL H. STONEMA). Rabbit polyclonal antibodies specific for human IRS-1 phosphorylated at Tyr896 (#3070), Ser307 (#2491), Ser337 (#2580), Ser636 (#2388), and Ser1101 (#2385) were purchased from Cell Signaling. Subject Selection Eighteen

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Phospho-IRS-1 (Ser302) (34C7) Rabbit mAb

Phospho-IRS-1 (Ser302) (34C7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

Citations (9)

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Phospho-IRS-1 (Ser302) (34C7) Rabbit mAb from Cell Signaling Technology

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