The BMP10 Polyclonal Antibody, PE-Cy5.5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to BMP10, and Bone Morphogenetic Protein 10. This antibody recognizes Homo Sapiens, and Human antigen. The BMP10 Polyclonal Antibody, PE-Cy5.5 Conjugated has been shown to work in the following applications: Western Blot.
Description
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines