The TXNRD1 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to thioredoxin reductase 1, and TXNRD1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The TXNRD1 Polyclonal Antibody has been shown to work in the following applications: Precipitation, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, Immunoprecipitation, and Western Blot.
Description
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid