The PHF8 Polyclonal Antibody from Bioss Inc. is a Rabbit Polyclonal antibody to PHD finger protein 8, and PHF8. This antibody recognizes Homo Sapiens, and Human antigen. The PHF8 Polyclonal Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Flow Cytometry.
Description
The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene