TIM-1/KIM-1/HAVCR Antibody

Product Specs
ItemTIM-1/KIM-1/HAVCR Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $429.00Supplier Page View Company Product Page
Catalog NumberNB100-56421
HostRabbit
FormatPBS
TargetTIM-1/KIM-1/HAVCR
ApplicationsWestern Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
ReactivityHuman,Mouse,Rat
Quantity0.1 mg (also 0.025 mg)
Conjugate/TagUnconjugated
Concentration1.0 mg/ml
ImmunogenA synthetic peptide (SPLYSYTTDGNDTVT) of human TIM-1 protein was used as immunogen for this antibody. This sequence corresponds to amino acids (aa) 248-262 of NP_036338 and aa 84-98 of EAW61615.1. Isoforms of TIM-1 have been described. For example, NP_036338 is 364 aa and EAW61615.1 is 194 aa. EAW61615.1 is referred to as isoform CRA_a
ClonalityPolyclonal
PurityImmunogen affinity purified
IsotypeIgG
Antibody TypePrimary Antibodies
NCBI Gene AliasesCD365, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1
NCBI Full Gene Namehepatitis A virus cellular receptor 1
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles
Research AreaCD Markers, Cellular Signaling, Immunology

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Isoforms of different molecular weights have been described for TIM-1. The sequence used for immunogen is conserved between TIM-1 (364aa, NP_036338) and TIM-1 isoform CRA_a (194aa, EAW61615.1). Therefore, the molecular weight observed in western blots may vary depending on the forms present.

Sizes Available: 0.1 mg (also 0.025 mg)

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Questions and Answers

What species does this TIM-1/KIM-1/HAVCR Antibody work with?

This antibody has been shown to be reactive with mouse, human, and rat samples, making it suitable for studies involving these species.

Can this antibody be used for immunocytochemistry, and are there any publications that support its use in this application?

Yes, the TIM-1/KIM-1/HAVCR Antibody can be used for immunocytochemistry. It has been cited in scientific literature for its application in this area, demonstrating its effectiveness in visualizing TIM-1 protein in cellular contexts.

What is the immunogen used for this antibody, and how does it relate to its specificity?

The immunogen for this antibody is a synthetic peptide corresponding to amino acids 248-262 of the human TIM-1 protein. This specific sequence contributes to the antibody's ability to recognize different isoforms of TIM-1, which have been described with varying molecular weights.

Is this antibody suitable for use in Western blotting, and what should I consider regarding its performance?

The TIM-1/KIM-1/HAVCR Antibody is suitable for Western blotting. When using it, researchers should consider the potential presence of isoforms of TIM-1, as these may affect the interpretation of results due to differences in molecular weight.