LSD1 (C69G12) Rabbit mAb 2184S from Cell Signaling Technology

Product Specs
ItemLSD1 (C69G12) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2184S
Quantity100 µl
ApplicationsW, IP, IHC-P, ChIP
ReactivityH, M, R, Mk
TargetLSD1
IsotypeIgG
HostRabbit
NCBI Gene AliasesAOF2, BHC110, CPRF, KDM1, LSD1
NCBI Full Gene Namelysine demethylase 1A
CloneC69G12
Molecular Weight110
ClonalityMonoclonal
Research AreaChromatin Regulation / Nuclear Function

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Cell Signaling Technology

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Phone: 877-616-CELL
Phone: 978-867-2388
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Website: http://www.cellsignal.com/

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(1) Potent and selective LSD1 inhibitor DC551040 reveals a promising combination therapy for AML with insight into epigenetic dysregulationSignal Transduct Target TherMarch 23, 2026Jiang Wang, Hanlin Wang, Runhua Du, Chunpu Li, Mingbo Su, Shuni Wang, Weijuan Kan, Guobin Liu, Yu Zhang, Xiaobei Hu, et al.2729) to eliminate nonspecific protein binding. Thereafter, antibodies targeting LSD1 (CST, Cat. No. 2184) or GFI1B (Santa Cruz, Cat. sc-28356) were supplemented into the lysates, followed by overnight incubation

(2) WNT inhibition activates interferon stimulated gene expression by alleviating epigenetic repression of endogenous retrovirusesScientific ReportsMarch 5, 2026Courtney M. Williams, Jessica Harper Calderon, Varenka Rodriguez DiBlasi, Louis Jinrui Liu, Samer Nuwayhid, Hannah Cevasco, Wei Wang, Rekha Soni, Christina Adler, David D’Ambrosio, et al.TBK1/NAK (3504), phospho-IRF-3 (37829), MDA-5 (5321), RIG-I (3743), P-STING (19781),STING (13647), LSD1 (2184), DNMT1 (5032), EZH2 (5246), ERK (4695), phospho-ERK (4370 ) were purchased from Cell Signaling Technologies

(3) Non-enzymatic ABHD6 interacts with Akt-FoxO1 axis to regulate selective hepatic insulin resistancebioRxivFebruary 17, 2026Guannan Li, Laurence T. Maeyens, Jiyuan Yin, Jan-Bernd Funcke, Chanmin Joung, Ruizhen Li, Ziying Xu, Ting Wu, Xin Li, Nisi Jiang, et al.#2972, 1:1000), phospho-4E-BP1 (Thr37/46) (CST, #2855, 1:1000), 4E-BP1 (CST, #9644, 1:1000), LSD1 (CST, #2184, 1:1000), β-Actin (Abclonal, AC004, 1:10,000), and GAPDH (Abclonal, AC002, 1:10,000). Immunofluorescence

(4) ORY-1001 Delays Retinal Photoreceptor Degeneration in rd10 Mice by Inhibiting H3K4me2 DemethylationBiology (Basel)January 13, 2026Xin Lu, Guang-Hua Pengmain antibodies used were anti-rhodopsin (catalog ab98887, Abcam, Cambridge, UK), anti-KDM1A (catalog 2184S, CST, USA), anti-H3K4me2 (catalog 9725S, CST, USA), anti-HDAC1 (catalog 34589S, CST, Danvers, MA, USA),

(5) Formate Reduces Ischemic Injury in Female Hearts Lacking Alcohol Dehydrogenase 5FASEB BioadvDecember 12, 2025Haley Garbus-Grant, Obialunanma V. Ebenebe-Kasonde, Raihan Kabir, Mark J. KohrCell Signaling #68796), lysine‐specific histone demethylase 1 (1:1000, Rabbit mAb, Cell Signaling #2184), methylenetetrahydrofolate dehydrogenase 1 like (1:1333, Rabbit mAb, Cell Signaling #14999), methylenetetrahydrofolate

(6) Combined Inhibition of Lysine-Specific Demethylase 1 and Kinase Signaling as a Preclinical Treatment Strategy in GlioblastomaNeuro-Oncology AdvancesNovember 20, 2025Lea M Stitzlein, Deokhwa Nam, Faith A Hernandez, Kareena H Patel, Alaina Poche, Huaxian Ma, Katie Impelman, Joy Gumin, Heping Wang, Jing Wang, et al.Ribosomal Protein (# 4857; RRID: AB_2181035), S6 ribosomal protein (# 2217; RRID: AB_331355), LSD1 (# 2184; RRID: AB_2070132), Actin (# 3700; RRID: AB_2242334), Tubulin (# 5568; RRID: AB_10694505), and GAPDH

(7) Tumoral RCOR2 promotes tumor development through dual epigenetic regulation of tumor plasticity and immunogenicityJournal of Clinical InvestigationSeptember 16, 2025Lei Bao, Ming Zhu, Maowu Luo, Ashwani Kumar, Yan Peng, Chao Xing, Yingfei Wang, Weibo Luosupplemented with 0.025% digitonin and 2 mM EDTA) with anti-LSD1 antibody (Cell Signaling Technology, catalog 2184) and incubated overnight at 4°C. After washing twice with Dig-wash buffer (wash buffer with 0.025% digitonin),

(8) Fbxo16 mediates degradation of NF-κB p65 subunit and inhibits inflammatory response in dendritic cellsFront ImmunolJune 3, 2025Akiko Sugimoto-Ishige, Aya Jodo, Takashi Tanaka(sc-7178), IκBα (sc-371) and PKC (sc-10800) antibodies were from Santa Cruz Biotechnology. Anti-LSD1 (#2184), cdc37 (#3604), Histone H3 (#4499) Lamin B1 (#12586) and Skp1 (#12248) antibodies were from Cell Signaling Technology

(9) MT1H inhibits the growth of gastric cancer by regulating SLC6A19/TTC39B/ADM2 and activating p53-dependent autophagySci RepMarch 18, 2025Yamin Xing, Guangyuan Li, Ganggang Li, Jixuan Xu, Ting Zhang, Mengxue Li, Chunxiao Gao, Miaoran Fu, Pengyuan Zheng, Xiufeng ChuChemiDoc™ XRS + system (Bio-Rad, Hercules, CA, USA). Antibodies and reagents For immunoblotting, LSD1 (2184), NF-κB p65 (8242T), RelB (4922T), Erk1/2 (9102), p-Erk1/2 (Thr202/Tyr204) (C4370S), and the Human Reactive Cell Death and Autophagy Antibody Sampler Kit

(10) Ubiquitination of gasdermin D N-terminal domain directs its membrane translocation and pore formation during pyroptosisCell Death DisMarch 17, 2025Xiufeng Chu, Ting Zhang, Ihtisham Bukhari, Mei Hu, Jixuan Xu, Yamin Xing, Xinfeng Liang, Zisen Zhang, Pengyuan ZhengMouse Reactive Pyroptosis Antibody Sampler Kit (#98303, 1:1000), TRAF1 (#4715, 1:1000), OTUB1 (#3783, 1:1000), and LSD1 (#2184, 1:1000) were purchased from Cell Signaling Technology. Anti-Flag (F1804, 1 µg/mL) and anti-HA (H6908,

(11) Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolismMolecular BrainNovember 27, 2024Ozan Baytas, Shawn M. Davidson, Julie A. Kauer, Eric M. Morrowrabbit anti-GRIA1 (abcam, ab31232, RRID:AB_2113447, 100 kDa, 1:1000), rabbit anti-LSD1 (CellSignaling, 2184, RRID:AB_2070132, 110 kDa, 1:1000), mouse anti-MTCO1 (abcam, ab14705, RRID:AB_2084810, 40 kDa, 1:2000),

(12) LSD1 Demethylates and Destabilizes Autophagy Protein LC3B in Ovarian CancerBiomoleculesOctober 29, 2024Mingyang Li, Jie Feng, Kangrong Zhao, Ting Huang, Bowen Zhang, Yifan Yang, Aiqin Sun, Qiong Lin, Genbao Shaoas follows: anti-LC3B (sc-376404) and anti-My (sc-40) from Santa Cruz (Dallas, TX, USA); anti-LSD1 (2184S) and anti-HA (3724S) from Cell Signaling Technology (Danvers, MA, USA); anti-α-tubulin (BS1699) from

(13) The transcription regulators ZNF750 and LSD1/KDM1A dampen inflammation on the skin’s surface by silencing pattern recognition receptorsImmunityOctober 1, 2024Ye Liu, Yifang Chen, Uyanga Batzorig, Jingting Li, Celia Fernández-Méndez, Samiksha Mahapatra, Fengwu Li, Shebin Sam, Tatsuya Dokoshi, Seung-Phil Hong, et al.anti-mouse,LI-COR,926–32212 IRDye 680RD Donkey anti-rabbit,LI-COR,926–68073 KDM1A/LSD1,Cell Signaling,2184 ,, Alexa 555 conjugated goat anti-Rabbit IgG,ThermoFisher,A21428 Alexa 488 conjugated donkey anti-rabbit

(14) A High-Throughput Screening Platform Identifies FDA-Approved Drugs That Inhibit SREBP Pathway ActivationACS Chemical BiologyAugust 16, 2024Chiaki T. T. Ishida, Casie S. Kubota, Evan Carlyle, Takashi Tsukamoto, Peter J. EspenshadeSanta Cruz Biotechnology, #SC-13551), SREBP-2 (2 μg/mL, R&D, #AF7119), KDM1A (1:1000, Cell Signaling, #2184), SCAP (1:1000) 34, alpha 1 sodium potassium ATPase (1:1000, Cell Signaling, #3010), FLAG M2 (1:1000,

(15) DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ERCell metabolismMarch 5, 2024Rong S, Xia M, Vale G, Wang S, Kim CW, Li S, McDonald JG, Radhakrishnan A, Horton JD.anti-Calnexin,Enzo,Cat#ADI-SPA-860-F Rabbit anti-β-actin,Cell Signaling,Cat#4970S Rabbit anti-LSD1,Cell Signaling,Cat#2184 Rabbit anti-SCD-1,Cell signal,Cat#2794 Mouse anti-CREB,ThermoFisher,Cat#35-0900 Mouse anti-EEA1,Sigma-Aldrich,Cat#E7659 Mouse

(16) Retrospective identification of cell-intrinsic factors that mark pluripotency potential in rare somatic cellsCell SystemsFebruary 21, 2024Naveen Jain, Yogesh Goyal, Margaret C. Dunagin, Christopher J. Cote, Ian A. Mellis, Benjamin Emert, Connie L. Jiang, Ian P. Dardani, Sam Reffsin, Miles Arnett, et al.1:1000 rabbit anti-SPP1 (Proteintech #22952–1-AP), 1:1000 rabbit anti-LSD1 (Cell Signaling Technology #2184S), 1:1000 rabbit anti-beta actin (Cell Signaling Technology #4970S), and 1:2000 rabbit anti-histone H3

(17) Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLCCell death & diseaseNovember 3, 2023Du L, Yang H, Ren Y, Ding Y, Xu Y, Zi X, Liu H, He P.ab125066), xCT (Abcam, ab37185), ATF4 (Cell Signaling Technology, 11815), LSD1 (Cell Signaling Technology, 2184), H3K9me2 (Cell Signaling Technology, 4658), YAP (Cell Signaling Technology, 14074), p-YAP (Cell Signaling Technology

(18) The Epigenetic Controller Lysine-Specific Demethylase 1 (LSD1) Regulates the Outcome of Hepatitis C Viral InfectionCellsNovember 3, 2023Georgia Papadopoulou, Stavroula Petroulia, Eirini Karamichali, Alexios Dimitriadis, Dimitrios Marousis, Elisavet Ioannidou, Panagiota Papazafiri, John Koskinas, Pelagia Foka, Urania GeorgopoulouDarmstadt, Germany) and incubated overnight with the following antibodies: β-actin (#3700), LSD1 (#2184), IFITM3 (#59212), p21 (#2947), Histone H3 (#9715), Occludin (#91131) and CD81 (#10037) by Cell Signalling

(19) The stem cell-supporting small molecule UM171 triggers Cul3-KBTBD4-mediated degradation of ELM2 domain-harboring proteinsThe Journal of biological chemistryMay 1, 2023Žemaitis K, Ghosh S, Hansson J, Subramaniam A.primary antibodies: RCOR1 (LS-B8157), MTA1 (5647T), MTA2 (15793) HDAC1 (34589T), HDAC2 (5113T), LSD1 (2184S), and ZNF217 (82306) from Cell Signaling Technology. RCOR2 (ab37113), RCOR3 (ab76921), MTA3 (ab176346)

(20) KDM1A inhibition increases UVA toxicity and enhances photodynamic therapy efficacyPhotodermatology, Photoimmunology & PhotomedicineMay 1, 2023Shaila Mudambi, Megan Fitzgerald, Paula Pera, Deschana Washington, Sarah Chamberlain, Eszter Fidrus, Csaba Hegedűs, Eva Remenyik, Gal Shafirstein, David Bellnier, et al.USA. All antibodies were purchased from Cell Signaling Technologies, Danvers, MA, USA KDM1A (cat no: 2184, final dilution 1:1000) and Lamin A/C (cat no: 2032, final dilution: 1:3000). Photodynamic therapy Cells

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4/3/2015Nuclear and cytoplasmic separation of fibroblasts Laura LecceNuclear and cytoplasmic proteins from human dermal fibroblasts were separated using salt buffers and centrifugation methods. Separated nuclear and cytoplasmic protein (5ugs) was loaded onto a western ... Read Review

LSD1 (C69G12) Rabbit mAb

LSD1 (C69G12) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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LSD1 (C69G12) Rabbit mAb from Cell Signaling Technology

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