Bcl-2 (8C8) Antibody sc-65392 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemBcl-2 (8C8) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-65392
Quantity200 µg/ml
ApplicationsWB, IP, IHC(P)
Reactivityhuman
FormatPurified
Conjugate/TagUnconjugated
Antibody TypePrimary Antibodies
Clone8C8
Hostmouse
TargetBcl-2
IsotypeIgG1
NCBI Gene AliasesBcl-2, PPP1R50
ClonalityMonoclonal
NCBI Full Gene NameBCL2 apoptosis regulator

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensatesActa Pharmaceutica Sinica BNovember 17, 2023Xiaohui Chen, Meichun Gao, Yongzhen Xia, Xin Wang, Jingbo Qin, Hongying He, Weirong Liu, Xiaowei Zhang, Shuangzhou Peng, Zhiping Zeng, et al.immunoprecipitation, anti-Flag (Sigma–Aldrich, F1804, dilution: 1:100), anti-Bcl-2 (Santa Cruz Biotechnology, sc-65392, dilution: 1:50) was utilized. For immunofluorescence staining, Fluorescent Probes of Mito-tracker deep

(2) PIK3R3, part of the regulatory domain of PI3K, is upregulated in sarcoma stem-like cells and promotes invasion, migration, and chemotherapy resistanceCell death & diseaseJuly 29, 2021Yoon C, Lu J, Ryeom SW, Simon MC, Yoon SS.Santa Cruz Biotechnology), cleaved caspase 3 (#9661; Cell Signaling), MMP-2 (Abcam, ab92536), Bcl-2 (sc-65392, Santa Cruz), CD133 (MBS462020; Miltenyi Biotec), p-AKT (Thr 308) (ab8933; Abcam), p-AKT(Ser 473) (#4060;

(3) PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomasOncogenesisJanuary 19, 2021Yoon C, Lu J, Yi BC, Chang KK, Simon MC, Ryeom S, Yoon SS.Abcam), Ki67 (ab15580) (all from Abcam), cleaved caspase-3 (#9661; Cell Signaling), Bcl-2 (Santa Cruz, sc-65392), or CD133 (MBS462020; MyBioSource) in a solution of PBS with 1% FBS and 0.1% Triton X-100 at 4 °C overnight.

(4) Mitochondrial division inhibitor-1 potentiates cisplatin-induced apoptosis via the mitochondrial death pathway in cholangiocarcinoma cellsBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieMarch 1, 2019Tusskorn O, Khunluck T, Prawan A, Senggunprai L, Kukongviriyapan V.

(5) Metformin sensitizes cholangiocarcinoma cell to cisplatin-induced cytotoxicity through oxidative stress mediated mitochondrial pathwayLife sciencesJanuary 15, 2019Wandee J, Prawan A, Senggunprai L, Kongpetch S, Kukongviriyapan V.

(6) Cytotoxic effect of Kalanchoe flammea and induction of intrinsic mitochondrial apoptotic signaling in prostate cancer cellsJournal of ethnopharmacologyAugust 10, 2018Arias-González I, García-Carrancá AM, Cornejo-Garrido J, Ordaz-Pichardo C.

(7) LRIG2 is a growth suppressor of Hec-1A and Ishikawa endometrial adenocarcinoma cells by regulating PI3K/AKT- and EGFR-mediated apoptosis and cell-cycleOncogenesisJanuary 23, 2018Suh DS, Park SE, Jin H, Lee K, Bae J.Antibodies against cytochrome c (sc-7159), EGFR (sc-03), MCL-1(sc-819), BCL-xL (sc-8392), BCL2A1, BCL-2 (sc-65392), BCL-W (sc-6418), BAK (sc-832), BAX (sc-493), BAD (sc-8044), BIM (sc-11425), p21 (sc-397), and β-actin

(8) Citrus nomilin down-regulates TNF-α-induced proliferation of aortic smooth muscle cells via apoptosis and inhibition of IκBEuropean journal of pharmacologySeptember 15, 2017Kim J, Chakraborty S, Jayaprakasha GK, Muthuchamy M, Patil BS.

(9) EGR2 is a gonadotropin-induced survival factor that controls the expression of IER3 in ovarian granulosa cellsBiochemical and biophysical research communicationsJanuary 22, 2017Jin H, Won M, Shin E, Kim HM, Lee K, Bae J.

(10) An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cellsPloS oneJanuary 1, 2013Sousa MM, Zub KA, Aas PA, Hanssen-Bauer A, Demirovic A, Sarno A, Tian E, Liabakk NB, Slupphaug G.

(11) Surface modification on acoustic wave biosensors for enhanced specificitySensors (Basel, Switzerland)January 1, 2012Onen O, Ahmad AA, Guldiken R, Gallant ND.

(12) A urinary Bcl-2 surface acoustic wave biosensor for early ovarian cancer detectionSensors (Basel, Switzerland)January 1, 2012Onen O, Sisman A, Gallant ND, Kruk P, Guldiken R.

(13) Differences in the cellular response and signaling pathways between cisplatin and monodentate organometallic Ru(II) antitumor complexes containing a terphenyl ligandMolecular pharmaceuticsJune 6, 2011Kisova A, Zerzankova L, Habtemariam A, Sadler PJ, Brabec V, Kasparkova J.

(14) Intensive resistance exercise induces lymphocyte apoptosis via cortisol and glucocorticoid receptor-dependent pathwaysJournal of applied physiology (Bethesda, Md. : 1985)May 1, 2011Krüger K, Agnischock S, Lechtermann A, Tiwari S, Mishra M, Pilat C, Wagner A, Tweddell C, Gramlich I, Mooren FC.

(15) Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinibCancer researchJanuary 15, 2011Chang WH, Liu TC, Yang WK, Lee CC, Lin YH, Chen TY, Chang JG.

(16) Changes in expression of some apoptotic markers in different types of human endometriumFolia biologicaJanuary 1, 2011Driák D, Dvorská M, Svandová I, Sehnal B, Benková K, Spůrková Z, Halaška M.

(17) Antileukemic activity of valproic acid in chronic lymphocytic leukemia B cells defined by microarray analysisLeukemiaDecember 1, 2009Stamatopoulos B, Meuleman N, De Bruyn C, Mineur P, Martiat P, Bron D, Lagneaux L.

(18) Soluble mediators from human neural stem cells play a critical role in suppression of T-cell activation and proliferationJournal of neuroscience researchAugust 1, 2009Kim SY, Cho HS, Yang SH, Shin JY, Kim JS, Lee ST, Chu K, Roh JK, Kim SU, Park CG.

(19) Small interfering RNA-directed knockdown of uracil DNA glycosylase induces apoptosis and sensitizes human prostate cancer cells to genotoxic stressMolecular cancer research : MCRAugust 1, 2009Pulukuri SM, Knost JA, Estes N, Rao JS.Abcam, Cambridge, MA). Antibodies against p53 (sc-53394), p21 (sc-51689), Bax (sc-70406) and Bcl2 (sc-65392) were obtained from Santa Cruz Biotechnology (Santa Cruz, CA). Semiquantitative reverse transcription-PCR

(20) Medulloblastomas: a correlative study of MIB-1 proliferation index along with expression of c-Myc, ERBB2, and anti-apoptotic proteins along with histological typing and clinical outcomeChild's nervous system : ChNS : official journal of the International Society for Pediatric NeurosurgeryJuly 1, 2009Das P, Puri T, Suri V, Sharma MC, Sharma BS, Sarkar C.

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Bcl-2 (8C8) Antibody

Bcl-2 (8C8) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

Citations (23)

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Bcl-2 (8C8) Antibody from Santa Cruz Biotechnology, Inc.

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