Bioss Inc.'s MARCH4 Polyclonal Antibody, PE-Cy5.5 Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The MARCH4 Polyclonal Antibody, PE-Cy5.5 Conjugated was generated using MARCHF4 as the antigen and it reacts with Homo Sapiens, and Human.
Description
MARCH4, an E3 ubiquitin protein ligase, may mediate ubiquitination of MHC I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin protein ligases accept ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates