Bioss Inc.'s Anti-MDM4 POLYCLONAL ANTIBODY, HRP Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, and Western Blot. The Anti-MDM4 POLYCLONAL ANTIBODY, HRP Conjugated was generated using MDM4, and MDM4 regulator of p53 as the antigen and it reacts with Mouse.
Description
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions