TSLP Antibody - BSA Free NB110-55234 from Novus Biologicals, a Bio-Techne Brand

Product Specs
ItemTSLP Antibody - BSA Free
CompanyNovus Biologicals, a Bio-Techne Brand
Price $399.00Supplier Page View Company Product Page
Catalog NumberNB110-55234
ImmunogenAntibody was raised against a peptide corresponding to 19 amino acids near the center of human TSLP. The immunogen is located within the amino acids 40-90 of TSLP
Concentration1.0 mg/ml
ApplicationsIF/IHC,ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry/ Immunofluorescence
ReactivityHuman,Mouse
Conjugate/TagUnconjugated
FormatPBS
TargetTSLP
Quantity0.05 mg
NCBI Full Gene Namethymic stromal lymphopoietin
ClonalityPolyclonal
PurityPeptide affinity purified
Molecular Weight18 kDa
IsotypeIgG
Research AreaInnate Immunity
Antibody TypePrimary Antibodies
StorageStore at 4C
HostRabbit

Specifications/Features

Available conjugates: Available conjugates: Unconjugated

Specificity: Human TSLP has 2 isoforms, including isoform 1 (159aa, 18kD) and isoform 2 (63aa, 7kD). Mouse TSLP has one isoform (140aa, 16kD) and Rat TSLP also has one isoform (135aa, 16kD). NB110-55234 can detect only longer human isoform, but cannot detect shorter human isoform, mouse and rat.

Sizes Available: 0.05 mg

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Questions and Answers

Can this TSLP antibody be used for immunoblotting in my experiments?

Yes, the TSLP antibody has been successfully utilized in immunoblotting, as demonstrated in studies such as those by Kanninen et al. (2023) and Kim et al. (2018), where it was employed to detect TSLP protein levels in various biological samples.

What species does this antibody react with, and is it suitable for human studies?

This TSLP antibody is reactive with both human (Homo sapiens) and mouse (Mus musculus) species, making it suitable for studies involving these organisms.

Has this antibody been used in any specific applications related to inflammation or immune response?

Yes, the TSLP antibody has been shown to play a role in studies related to inflammation and immune response, particularly in the context of atopic dermatitis, as indicated by its use in the research by Kim et al. (2018), where it was involved in evaluating the immune response in a mouse model of the disease.

Is there any information on the expression of TSLP in human tissues that could guide my research?

The expression of TSLP has been documented in human amniotic fluid and chorioamniotic membranes, particularly in the context of spontaneous preterm labor, as reported by Kanninen et al. (2023). This suggests that the antibody could be valuable for investigating TSLP's role in human inflammatory responses.

Novus Biologicals, a Bio-Techne Brand

United States: 10771 E Easter Ave

Centennial, Colorado 80112

United States

Phone:
303-730-1950
888-506-6887

Email: novus@novusbio.com

Company Profile

Website: https://www.novusbio.com

(1) Thymic stromal lymphopoietin participates in the host response to intra-amniotic inflammation leading to preterm labor and birthHuman immunologySeptember 1, 2023Kanninen T, Tao L, Romero R, Xu Y, Arenas-Hernandez M, Galaz J, Liu Z, Miller D, Levenson D, Greenberg JM, et al.room temperature and then probed overnight at 4°C with the following antibodies: anti-human TSLP (Cat# NB110-55234; Novus Biologicals, Littleton, CO, USA), anti-human TSLPR (Cat# PA5-20378; Invitrogen), or anti-human

(2) Interactions of thymic stromal lymphopoietin with interleukin-4 in adaptive immunity during Aspergillus fumigatus keratitisInternational journal of ophthalmologyJanuary 1, 2021Chen C, Dai CY, Han F, Wu JY, Sun L, Wu XY.

(3) Topical administration of EGF suppresses immune response and protects skin barrier in DNCB-induced atopic dermatitis in NC/Nga miceScientific reportsAugust 9, 2018Kim YJ, Choi MJ, Bak DH, Lee BC, Ko EJ, Ahn GR, Ahn SW, Kim MJ, Na J, Kim BJ.Cell Signaling Technology, Inc.), anti-PAR-2 (1:1000; sc-8205; Santa Cruz Biotechnology), anti-TSLP (1:2500; NB110-55234; Novus Biologicals, Littleton, CO, USA), and anti-β-actin (1:1000; sc-47778; Santa Cruz Biotechnology)

(4) Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory diseaseThe Journal of allergy and clinical immunologyMay 1, 2016Buchheit KM, Cahill KN, Katz HR, Murphy KC, Feng C, Lee-Sarwar K, Lai J, Bhattacharyya N, Israel E, Boyce JA, et al.specific, a blot of 4 nasal polyp samples was probed with a new additional polyclonal anti-TSLP antibody, NB110-55234 (Novus Biologicals, Littleton, CO), which was raised against a known 19 amino acid TLSP peptide. That

(5) Peroxisome proliferator-activated receptor-γ and thymic stromal lymphopoietin are involved in the pathophysiology of childhood coeliac diseaseVirchows Archiv : an international journal of pathologyOctober 1, 2014Sziksz E, Molnár K, Lippai R, Pap D, Onody A, Veres-Székely A, Vörös P, Szabó D, Győrffy H, Veres G, et al.

(6) External Application of Fermented Olive Flounder (Paralichthys olivaceus) Oil Alleviates Inflammatory Responses in 2,4-Dinitrochlorobenzeneinduced Atopic Dermatitis Mouse ModelToxicological researchSeptember 1, 2012Han SC, Kang GJ, Ko YJ, Kang HK, Moon SW, Ann YS, Yoo ES.

(7) Fermented fish oil suppresses T helper 1/2 cell response in a mouse model of atopic dermatitis via generation of CD4+CD25+Foxp3+ T cellsBMC immunologyAugust 9, 2012Han SC, Kang GJ, Ko YJ, Kang HK, Moon SW, Ann YS, Yoo ES.

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