MHC class II (ER-TR3) Antibody sc-59318 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMHC class II (ER-TR3) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-59318
Antibody TypePrimary Antibodies
Quantity200 µg/ml
CloneER-TR3
ApplicationsWB, IP, IF, IHC(P), FCM, ELISA
Reactivitymouse, rat, human
Hostrat
Conjugate/TagUnconjugated
FormatPurified
ClonalityMonoclonal
TargetMHC class II
NCBI Full Gene Namehistocompatibility 2, class II antigen E alpha, major histocompatibility complex, class II, DR alpha
NCBI Gene AliasesMHC-H2-Ea, H-2Ea, HLA-DRA1, H2-Ea-ps, I-Ealpha, Ia3, E-alpha-f, Ia-3
IsotypeIgG2b

Questions and Answers

Can this antibody be used for immunohistochemistry in mouse tissues?

Yes, the MHC class II (ER-TR3) antibody has been utilized in immunohistochemical analysis of mouse tissues, as demonstrated in studies where it was employed to detect MHC class II expression in various experimental models, including those related to asthma and leprosy .

What specific applications has this antibody been shown to work in?

The MHC class II (ER-TR3) antibody has been shown to work in several applications, including Western blotting, ELISA, flow cytometry, immunofluorescence, immunohistochemistry, and immunoprecipitation .

Is this antibody effective in studies involving T-helper cell responses?

Yes, the MHC class II (ER-TR3) antibody has been effectively used in studies examining T-helper cell responses, particularly in the context of asthma models where it helped assess the expression of CD4+ T cells and related cytokines .

What species does this antibody react with?

The MHC class II (ER-TR3) antibody is reactive with mouse, human, and rat tissues, making it versatile for use in various species in immunological studies .

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Exosomes Derived from Bone Marrow Dendritic Cells Exhibit Protective and Therapeutic Potential Against Chemically Induced Chronic Pancreatitis in RatsInflammationOctober 19, 2024Shaimaa M. Bashir, Sherine M. Rizk, Mohammed M. Nooh, Hebatullah S. Helmy(SANTA CRUZ BIOTECHNOLOGY, INC, USA (H-10): sc-13128) and PE-labeled MHCII (SANTA CRUZ BIOTECHNOLOGY, INC, USA (ER-TR3): sc-59318). Purification and Identification of BMDCs Derived Exosomes As shown in Fig. 1, The cell suspension

(2) Increased efficiency of peripheral nerve regeneration using supercritical carbon dioxide-based decellularization in acellular nerve graftScientific ReportsOctober 10, 2024Soon Jin Choi, Jeonghun Han, Young Ho Shin, Jae Kwang Kimantibodies against MHC1 (1:1,000, Cat# SC-55582, Santa Cruz Biotechnology, USA), MHC2 (1:1,000, Cat# SC-59318, Santa Cruz Biotechnology, USA) and β-actin (1:1000, Cat# SC-47778, Santa Cruz Biotechnology, USA) overnight

(3) In vivo edited eosinophils reconcile antigen specific Th2 response and mitigate airway allergyCell Communication and SignalingSeptember 30, 2024Xiangqian Luo, Jinna Yang, Haoyue Zheng, Yuanyi Zhang, Lihua Mo, Qinmiao Huang, Gaohui Wu, Jianwen Zhong, Yu Liu, Gui Yang, et al.F4/80 (sc-52664, AF648), CD19 (sc-390244, AF594), CD44 (sc-53068, AF790), OVA (sc-65984) and MHC II (sc-59318) were purchased from Santa Cruz Biotech (Santa Cruz, CA). PD1/PD-L1-IN-3 was purchased from Xinyan Bomei

(4) Chimeric Antigen-LgDNA Nanoparticles Attenuate Airway Th2 PolarizationInternational Journal of NanomedicineSeptember 27, 2024Ruien Chen, Huamei Zou, Xiuwen Ye, Bailing Xie, Aizhi Zhang, Lihua Mo, Yu Liu, Huanping Zhang, Gui Yang, Pingchang YangF4/80 (sc-52664, AF648), IL-4 (sc-32242, AF700), CD44 (sc-53068, AF790), OVA (sc-65984), and MHC II (sc-59318) were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). IETD-CHO was purchased from Sigma–Aldrich

(5) Microglial CD74 Expression Is Regulated by TGFβ SignalingInternational journal of molecular sciencesSeptember 6, 2022Jahn J, Bollensdorf A, Kalischer C, Piecha R, Weiß-Müller J, Potru PS, Ruß T, Spittau B.019-19741), anti-GFP (Abcam, ab13970), anti-CD74 (BD Biosciences, 55317), and anti-MHC-II (Santa Cruz, sc-59318) primary antibodies. Alexa FluorR 488 anti-chicken (Abcam, ab150173), Alexa FluorR 488 anti-rat (Abcam,

(6) Two distinct receptor-binding domains of human glycyl-tRNA synthetase 1 displayed on extracellular vesicles activate M1 polarization and phagocytic bridging of macrophages to cancer cellsCancer lettersJuly 28, 2022Park MC, Goughnour PC, Jun S, Cho S, Song E, Kim SB, Kim HY, Hyun JK, Kim P, Jung HS, et al.

(7) Analysis of the myeloid-derived suppressor cells and annexin A1 in multibacillary leprosy and reactional episodesBMC infectious diseasesOctober 9, 2021da Silva SF, da Silva Cavalcante LR, Fonseca Junior EA, da Silva JM, Lopes JC, Damazo AS.used a monoclonal mouse IgG anti-CD14 (SANTA CRUZ biotechnology, 1:100 in 1% BSA), rat anti-MHCII (sc-59318; Santa Cruz Biotechnology Inc., Santa Cruz, CA 1:100), goat anti-CD11b (1:50 in 1% BSA). For identification

(8) Efficient Delivery of Chlorin e6 by Polyglycerol-Coated Iron Oxide Nanoparticles with Conjugated Doxorubicin for Enhanced Photodynamic Therapy of MelanomaMolecular pharmaceuticsSeptember 6, 2021Li TF, Xu HZ, Xu YH, Yu TT, Tang JM, Li K, Wang C, Peng XC, Li QR, Sang XY, et al.

(9) Synergy of nanodiamond-doxorubicin conjugates and PD-L1 blockade effectively turns tumor-associated macrophages against tumor cellsJournal of nanobiotechnologySeptember 6, 2021Xu HZ, Li TF, Wang C, Ma Y, Liu Y, Zheng MY, Liu ZJ, Chen JB, Li K, Sun SK, et al.(20991-1-AP, Proteintech), CD206(ab64693, Abcam), CD80 (BS-2211R,BIOSS), CD86 (ab213044, Abcam), MHCII (sc-59318, Santa Cruz), KI67 (ab16667, Abcam), PCNA (ab92552, Abcam), BAX (50599-2-lg, Proteintech), CASPASE3

(10) Murine Susceptibility to Leishmania amazonensis Infection Is Influenced by Arginase-1 and Macrophages at the Lesion SiteFrontiers in cellular and infection microbiologyJanuary 1, 2021Tomiotto-Pellissier F, Miranda-Sapla MM, Silva TF, Bortoleti BTDS, Gonçalves MD, Concato VM, Rodrigues ACJ, Detoni MB, Costa IN, Panis C, et al.iNOS (NOS2, dilution 1:500, Santa Cruz Biotechnology, USA, Cat. SC7271), MHC-II (1:500, Santa Cruz, SC59318), arginase-1 (Arg-1, 1:600, Santa Cruz, SC18351), and CD206 (1:400, Santa Cruz, SC34577) for 2 h at

(11) Activation of the executioner caspases-3 and -7 promotes microglial pyroptosis in models of multiple sclerosisJournal of neuroinflammationAugust 29, 2020McKenzie BA, Fernandes JP, Doan MAL, Schmitt LM, Branton WG, Power C.Technology #9731),1:200 Cleaved GSDMD (provided by FS),1:100 MHC Class II (Santa Cruz Biotechnology sc-59318),1:200

(12) Allium hookeri root extract regulates asthmatic changes through immunological modulation of Th1/Th2‑related factors in an ovalbumin‑induced asthma mouse modelMolecular medicine reportsOctober 1, 2019Bok SH, Seo JH, Bae CS, Kang B, Cho SS, Park DH.

(13) Analysis of macrophage subtypes and annexin A1 expression in lesions of patients with cutaneous leishmaniasisRevista da Sociedade Brasileira de Medicina TropicalJuly 26, 2019Joselina Maria da Silva, Helen Aguiar Lemes da Silva, Carolina Zelenski, Jéssica Azevedo de Moraes Souza, Marcia Hueb, Amílcar Sabino Damazoanti-CD163 (Cell Marque, USA, clone EP152, 1:200); to identify M1 macrophages mouse anti-MHC II was used (sc-59318; Santa Cruz Biotechnology Inc., Santa Cruz, CA, 1:100); to identify M2 macrophages, mouse anti-CD206 (R & D Systems

(14) Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagyActa biomaterialiaMarch 1, 2019Li TF, Xu YH, Li K, Wang C, Liu X, Yue Y, Chen Z, Yuan SJ, Wen Y, Zhang Q, et al.

(15) Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastomaBiomaterialsOctober 1, 2018Li TF, Li K, Zhang Q, Wang C, Yue Y, Chen Z, Yuan SJ, Liu X, Wen Y, Han M, et al.

(16) Mycoleptodonoides aitchisonii suppresses asthma via Th2 and Th1 cell regulation in an ovalbumin‑induced asthma mouse modelMolecular medicine reportsJanuary 1, 2018Lee SY, Bae CS, Seo JH, Cho SS, Bae MS, Oh DS, Park DH.(cat no. 250585; 1:100; Abbiotec, San Diego, CA, USA), rat anti-mouse MHC class II monoclonal (cat no. sc-59318; 1:100; Santa Cruz Biotechnology, Inc.), rabbit anti-mouse Tbx21/T-bet polyclonal (cat no. bs-3599R;

(17) Bacillus subtilis KCTC 11782BP-produced alginate oligosaccharide effectively suppresses asthma via T-helper cell type 2-related cytokinesPloS oneJanuary 1, 2015Bang MA, Seo JH, Seo JW, Jo GH, Jung SK, Yu R, Park DH, Park SJ.polyclonal antibody (Bioss, bs-0649R), rat anti-mouse MHC class II monoclonal antibody(Santa Cruz, sc-59318), rabbit anti-mouse Tbx21/T-bet polyclonal antibody (Bioss, bs-3599R), goat anti-mouse GATA-3 antibody

(18) A role for intestinal alkaline phosphatase in the maintenance of local gut immunityDigestive diseases and sciencesApril 1, 2011Chen KT, Malo MS, Beasley-Topliffe LK, Poelstra K, Millan JL, Mostafa G, Alam SN, Ramasamy S, Warren HS, Hohmann EL, et al.monoclonal antibody against a subunit of mouse MHC class II molecule was used as a primary antibody (sc-59318; Santa Cruz Biotechnology Inc, Santa Cruz, CA); rabbit anti-rat IgG was used as a secondary antibody

(19) A Role for Intestinal Alkaline Phosphatase in the Maintenance of Local Gut ImmunityJournal of Surgical ResearchFebruary 1, 2010K.T. Chen et al.monoclonal antibody against a subunit of mouse MHC class II molecule was used as a primary antibody (sc-59318; Santa Cruz Biotechnology Inc, Santa Cruz, CA); rabbit anti-rat IgG was used as a secondary antibody

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MHC class II (ER-TR3) Antibody

MHC class II (ER-TR3) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MHC class II (ER-TR3) Antibody from Santa Cruz Biotechnology, Inc.

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